{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T14:44:04Z","timestamp":1692974644877},"reference-count":82,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2016.00223","type":"journal-article","created":{"date-parts":[[2016,12,15]],"date-time":"2016-12-15T07:03:05Z","timestamp":1481785385000},"update-policy":"http:\/\/dx.doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Developmental Changes in Pain and Spinal Immune Gene Expression after Radicular Trauma in the Rat"],"prefix":"10.3389","volume":"7","author":[{"given":"Gordon A.","family":"Barr","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaoning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine L.","family":"Weisshaar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth A.","family":"Winkelstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2016,12,15]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1093\/oxfordjournals.bmb.a072499","article-title":"Development of pain mechanisms","volume":"47","author":"Fitzgerald","year":"1991","journal-title":"Br Med Bull"},{"key":"B2","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1097\/00001756-200102120-00042","article-title":"Long-term effects of short-lasting early local inflammatory insult","volume":"12","author":"Lidow","year":"2001","journal-title":"Neuroreport"},{"key":"B3","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1126\/science.289.5479.628","article-title":"Altered nociceptive neuronal circuits after neonatal peripheral inflammation","volume":"289","author":"Ruda","year":"2000","journal-title":"Science"},{"key":"B4","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/S0306-4522(98)00734-9","article-title":"Time-course of spinal sensitization following carrageenan-induced inflammation in the young rat: a comparative electrophysiological and behavioural study in vitro and in vivo","volume":"92","author":"Hedo","year":"1999","journal-title":"Neuroscience"},{"key":"B5","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/0304-3959(94)00271-F","article-title":"Nerve growth factor induces mechanical allodynia associated with novel a fibre-evoked spinal reflex activity and enhanced neurokinin-1 receptor activation in the rat","volume":"62","author":"Thompson","year":"1995","journal-title":"Pain"},{"key":"B6","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/S0091-3057(97)00602-3","article-title":"Maturation of the biphasic behavioral and heart rate response in the formalin test","volume":"60","author":"Barr","year":"1998","journal-title":"Pharmacol Biochem Behav"},{"key":"B7","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1038\/nrn1701","article-title":"The development of nociceptive circuits","volume":"6","author":"Fitzgerald","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"B8","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/S0304-3959(97)00119-X","article-title":"Formalin-induced c-fos expression in the spinal cord of fetal rats","volume":"73","author":"Yi","year":"1997","journal-title":"Pain"},{"key":"B9","doi-asserted-by":"publisher","first-page":"3662","DOI":"10.1523\/JNEUROSCI.0348-06.2006","article-title":"Cortical pain responses in human infants","volume":"26","author":"Slater","year":"2006","journal-title":"J Neurosci"},{"key":"B10","volume-title":"Pain in Neonates and Infants","author":"Anand","year":"2007"},{"key":"B11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/AIA.0b013e3180341961","article-title":"Development of pain: maturation of spinal inhibitory networks","volume":"45","author":"Baccei","year":"2007","journal-title":"Int Anesthesiol Clin"},{"key":"B12","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1111\/j.1460-9568.2005.04529.x","article-title":"A postnatal switch in GABAergic control of spinal cutaneous reflexes","volume":"23","author":"Hathway","year":"2006","journal-title":"Eur J Neurosci"},{"key":"B13","doi-asserted-by":"publisher","first-page":"4749","DOI":"10.1523\/JNEUROSCI.5211-03.2004","article-title":"Development of GABAergic and glycinergic transmission in the neonatal rat dorsal horn","volume":"24","author":"Baccei","year":"2004","journal-title":"J Neurosci"},{"key":"B14","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1136\/archdischild-2013-304208","article-title":"Neuropathic pain in children","volume":"99","author":"Howard","year":"2014","journal-title":"Arch Dis Child"},{"key":"B15","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1093\/brain\/awf017","article-title":"Restoration of sensory function and lack of long-term chronic pain syndromes after brachial plexus injury in human neonates","volume":"125","author":"Anand","year":"2002","journal-title":"Brain"},{"key":"B16","doi-asserted-by":"publisher","first-page":"S33","DOI":"10.4065\/mcp.2009.0647","article-title":"Neuropathic pain in children: special considerations","volume":"85","author":"Walco","year":"2010","journal-title":"Mayo Clin Proc"},{"key":"B17","doi-asserted-by":"publisher","first-page":"14415","DOI":"10.1523\/JNEUROSCI.4569-09.2009","article-title":"T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity","volume":"29","author":"Costigan","year":"2009","journal-title":"J Neurosci"},{"key":"B18","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1016\/j.expneurol.2015.07.013","article-title":"Nerve injury and neuropathic pain \u2013 a question of age","volume":"275","author":"Fitzgerald","year":"2016","journal-title":"Exp Neurol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1016\/0304-3940(96)12623-9","article-title":"Neuropathic pain in neonatal rats","volume":"209","author":"Lee","year":"1996","journal-title":"Neurosci Lett"},{"key":"B20","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/j.pain.2005.03.016","article-title":"The ontogeny of neuropathic pain: postnatal onset of mechanical allodynia in rat spared nerve injury (SNI) and chronic constriction injury (CCI) models","volume":"115","author":"Howard","year":"2005","journal-title":"Pain"},{"key":"B21","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.neures.2008.04.012","article-title":"Developmental characteristics of neuropathic pain induced by peripheral nerve injury of rats during neonatal period","volume":"61","author":"Back","year":"2008","journal-title":"Neurosci Res"},{"key":"B22","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.pain.2006.09.018","article-title":"Spinal microglia and neuropathic pain in young rats","volume":"128","author":"Moss","year":"2007","journal-title":"Pain"},{"key":"B23","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.pain.2009.03.022","article-title":"Brief, low frequency stimulation of rat peripheral C-fibres evokes prolonged microglial-induced central sensitization in adults but not in neonates","volume":"144","author":"Hathway","year":"2009","journal-title":"Pain"},{"key":"B24","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.bbi.2006.10.007","article-title":"Age-related changes in the spinal cord microglial and astrocytic response profile to nerve injury","volume":"21","author":"Vega-Avelaira","year":"2007","journal-title":"Brain Behav Immun"},{"key":"B25","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1186\/1744-8069-5-70","article-title":"Differential regulation of immune responses and macrophage\/neuron interactions in the dorsal root ganglion in young and adult rats following nerve injury","volume":"5","author":"Vega-Avelaira","year":"2009","journal-title":"Mol Pain"},{"key":"B26","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.mcn.2005.11.008","article-title":"Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain","volume":"31","author":"Zhao","year":"2006","journal-title":"Mol Cell Neurosci"},{"key":"B27","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1097\/00000542-200308000-00027","article-title":"Age-dependent responses to thermal hyperalgesia and mechanical allodynia in a rat model of acute postoperative pain","volume":"99","author":"Ririe","year":"2003","journal-title":"Anesthesiology"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1146\/annurev.neuro.051508.135531","article-title":"Neuropathic pain: a maladaptive response of the nervous system to damage","volume":"32","author":"Costigan","year":"2009","journal-title":"Annu Rev Neurosci"},{"key":"B29","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s12264-012-1219-5","article-title":"Emerging role of toll-like receptors in the control of pain and itch","volume":"28","author":"Liu","year":"2012","journal-title":"Neurosci Bull"},{"key":"B30","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.pain.2012.01.004","article-title":"Pain\u2019s peptide signature","volume":"153","author":"Costigan","year":"2012","journal-title":"Pain"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1689","DOI":"10.2174\/138920111798357302","article-title":"The dynamic TRPA1 channel: a suitable pharmacological pain target?","volume":"12","author":"Garrison","year":"2011","journal-title":"Curr Pharm Biotechnol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/j.jpain.2011.12.002","article-title":"Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of paclitaxel-induced painful neuropathy","volume":"13","author":"Zhang","year":"2012","journal-title":"J Pain"},{"key":"B33","doi-asserted-by":"publisher","first-page":"G1085","DOI":"10.1152\/ajpgi.00542.2011","article-title":"Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome","volume":"302","author":"Feng","year":"2012","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"B34","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1097\/ALN.0b013e31820a4bf3","article-title":"Spinal macrophage migration inhibitory factor is a major contributor to rodent neuropathic pain-like hypersensitivity","volume":"114","author":"Wang","year":"2011","journal-title":"Anesthesiology"},{"key":"B35","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1016\/j.neuroscience.2011.10.017","article-title":"Brain-derived neurotrophic factor-activated astrocytes produce mechanical allodynia in neuropathic pain","volume":"199","author":"Zhang","year":"2011","journal-title":"Neuroscience"},{"key":"B36","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1007\/s00702-011-0713-7","article-title":"The effect of intrathecal administration of glial activation inhibitors on dorsal horn BDNF overexpression and hind paw mechanical allodynia in spinal nerve ligated rats","volume":"119","author":"Zhang","year":"2012","journal-title":"J Neural Transm (Vienna)"},{"key":"B37","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.pharmthera.2010.01.002","article-title":"Chemokines, neuronal-glial interactions, and central processing of neuropathic pain","volume":"126","author":"Gao","year":"2010","journal-title":"Pharmacol Ther"},{"key":"B38","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1016\/j.nurt.2010.05.016","article-title":"Targeting astrocyte signaling for chronic pain","volume":"7","author":"Gao","year":"2010","journal-title":"Neurotherapeutics"},{"key":"B39","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.biotechadv.2011.05.014","article-title":"Therapeutic targeting of innate immunity with toll-like receptor 4 (TLR4) antagonists","volume":"30","author":"Peri","year":"2012","journal-title":"Biotechnol Adv"},{"key":"B40","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jneuroim.2010.08.013","article-title":"The neuro-immune balance in neuropathic pain: involvement of inflammatory immune cells, immune-like glial cells and cytokines","volume":"229","author":"Austin","year":"2010","journal-title":"J Neuroimmunol"},{"issue":"6","key":"B41","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1016\/j.bbi.2012.03.004","article-title":"Heterogeneity of macrophages in injured trigeminal nerves: cytokine\/chemokine expressing vs. phagocytic macrophages","volume":"26","author":"Lee","year":"2012","journal-title":"Brain Behav Immun"},{"key":"B42","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1016\/j.expneurol.2011.12.021","article-title":"Immune responses of microglia in the spinal cord: contribution to pain states","volume":"234","author":"Schomberg","year":"2012","journal-title":"Exp Neurol"},{"key":"B43","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1002\/eji.200737485","article-title":"CNS-infiltrating CD4(+) T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain","volume":"38","author":"Cao","year":"2008","journal-title":"Eur J Immunol"},{"key":"B44","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/j.neuroscience.2004.08.035","article-title":"T lymphocytes play a role in neuropathic pain following peripheral nerve injury in rats","volume":"129","author":"Moalem","year":"2004","journal-title":"Neuroscience"},{"key":"B45","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.jneuroim.2008.04.011","article-title":"Glia in pathological pain: a role for fractalkine","volume":"198","author":"Milligan","year":"2008","journal-title":"J Neuroimmunol"},{"key":"B46","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1038\/nrn2533","article-title":"Pathological and protective roles of glia in chronic pain","volume":"10","author":"Milligan","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"B47","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1742-2094-7-27","article-title":"TNF-alpha and neuropathic pain \u2013 a review","volume":"7","author":"Leung","year":"2010","journal-title":"J Neuroinflammation"},{"key":"B48","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1523\/JNEUROSCI.2315-14.2015","article-title":"Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation","volume":"35","author":"McKelvey","year":"2015","journal-title":"J Neurosci"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1109\/TBME.2015.2399374","article-title":"Burst and tonic spinal cord stimulation differentially activate GABAergic mechanisms to attenuate pain in a rat model of cervical radiculopathy","volume":"62","author":"Crosby","year":"2015","journal-title":"IEEE Trans Biomed Eng"},{"key":"B50","doi-asserted-by":"publisher","first-page":"2429","DOI":"10.1089\/neu.2011.1918","article-title":"Schwann cell proliferation and macrophage infiltration are evident at day 14 after painful cervical nerve root compression in the rat","volume":"28","author":"Chang","year":"2011","journal-title":"J Neurotrauma"},{"key":"B51","doi-asserted-by":"publisher","first-page":"1924","DOI":"10.1097\/01.brs.0000176239.72928.00","article-title":"Transient cervical nerve root compression in the rat induces bilateral forepaw allodynia and spinal glial activation: mechanical factors in painful neck injuries","volume":"30","author":"Hubbard","year":"2005","journal-title":"Spine"},{"key":"B52","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.jpain.2008.07.008","article-title":"Cytokine mRNA expression in painful radiculopathy","volume":"10","author":"Rothman","year":"2009","journal-title":"J Pain"},{"key":"B53","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.neuroscience.2012.02.027","article-title":"Transient nerve root compression load and duration differentially mediate behavioral sensitivity and associated spinal astrocyte activation and mGLuR5 expression","volume":"209","author":"Nicholson","year":"2012","journal-title":"Neuroscience"},{"key":"B54","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/0165-3806(87)90105-2","article-title":"Morphine- and ketocyclazocine-induced analgesia in the developing rat: differences due to type of noxious stimulus and body topography","volume":"429","author":"Giordano","year":"1987","journal-title":"Brain Res"},{"key":"B55","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/0165-3806(88)90174-5","article-title":"Analgesic effects of intrathecally applied noradrenergic compounds in the developing rat: differences due to thermal vs mechanical nociception","volume":"469","author":"Hughes","year":"1988","journal-title":"Brain Res"},{"key":"B56","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1038\/nn.2403","article-title":"Transitions in infant learning are modulated by dopamine in the amygdala","volume":"12","author":"Barr","year":"2009","journal-title":"Nat Neurosci"},{"key":"B57","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1177\/29.4.6166661","article-title":"Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures","volume":"29","author":"Hsu","year":"1981","journal-title":"J Histochem Cytochem"},{"key":"B58","doi-asserted-by":"publisher","first-page":"4991","DOI":"10.1523\/JNEUROSCI.5216-10.2011","article-title":"The role of the medial prefrontal cortex in innate fear regulation in infants, juveniles, and adolescents","volume":"31","author":"Chan","year":"2011","journal-title":"J Neurosci"},{"key":"B59","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0304-3959(00)00276-1","article-title":"Spared nerve injury: an animal model of persistent peripheral neuropathic pain","volume":"87","author":"Decosterd","year":"2000","journal-title":"Pain"},{"key":"B60","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1186\/s12974-015-0318-4","article-title":"Evidence for a distinct neuro-immune signature in rats that develop behavioural disability after nerve injury","volume":"12","author":"Austin","year":"2015","journal-title":"J Neuroinflammation"},{"key":"B61","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.pnpbp.2015.07.005","article-title":"Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats","volume":"64","author":"Kwiatkowski","year":"2016","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"B62","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.jneuroim.2016.04.017","article-title":"Direct and indirect pharmacological modulation of CCL2\/CCR2 pathway results in attenuation of neuropathic pain \u2013 in vivo and in vitro evidence","volume":"297","author":"Piotrowska","year":"2016","journal-title":"J Neuroimmunol"},{"key":"B63","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1016\/j.pbb.2012.12.014","article-title":"Dissociated modulation of conditioned place-preference and mechanical hypersensitivity by a TRPA1 channel antagonist in peripheral neuropathy","volume":"104","author":"Wei","year":"2013","journal-title":"Pharmacol Biochem Behav"},{"key":"B64","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1016\/j.pain.2012.03.008","article-title":"Absence of C-C motif chemokine ligand 5 in mice leads to decreased local macrophage recruitment and behavioral hypersensitivity in a murine neuropathic pain model","volume":"153","author":"Liou","year":"2012","journal-title":"Pain"},{"key":"B65","doi-asserted-by":"publisher","first-page":"1194","DOI":"10.3892\/etm.2013.1296","article-title":"Anti-interleukin-6 receptor antibody reduces neuropathic pain following spinal cord injury in mice","volume":"6","author":"Murakami","year":"2013","journal-title":"Exp Ther Med"},{"key":"B66","doi-asserted-by":"publisher","first-page":"e92073","DOI":"10.1371\/journal.pone.0092073","article-title":"Gene therapy for neuropathic pain by silencing of TNF-alpha expression with lentiviral vectors targeting the dorsal root ganglion in mice","volume":"9","author":"Ogawa","year":"2014","journal-title":"PLoS One"},{"key":"B67","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.jpain.2012.09.015","article-title":"Peritoneal administration of Met-RANTES attenuates inflammatory and nociceptive responses in a murine neuropathic pain model","volume":"14","author":"Liou","year":"2013","journal-title":"J Pain"},{"key":"B68","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/BRS.0b013e3181c67f1e","article-title":"The reactions of glial cells and endoneurial macrophages in the dorsal root ganglion and their contribution to pain-related behavior after application of nucleus pulposus onto the nerve root in rats","volume":"35","author":"Otoshi","year":"2010","journal-title":"Spine"},{"key":"B69","doi-asserted-by":"publisher","first-page":"8489","DOI":"10.1523\/JNEUROSCI.2552-08.2008","article-title":"Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats","volume":"28","author":"Latremoliere","year":"2008","journal-title":"J Neurosci"},{"key":"B70","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1016\/S0006-8993(00)02807-9","article-title":"Intrathecal anti-IL-6 antibody and IgG attenuates peripheral nerve injury-induced mechanical allodynia in the rat: possible immune modulation in neuropathic pain","volume":"879","author":"Arruda","year":"2000","journal-title":"Brain Res"},{"key":"B71","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1016\/j.ejpain.2008.09.009","article-title":"Tumor necrosis factor receptor 1 induces interleukin-6 upregulation through NF-kappaB in a rat neuropathic pain model","volume":"13","author":"Lee","year":"2009","journal-title":"Eur J Pain"},{"key":"B72","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1744-8069-8-30","article-title":"The emergence of adolescent onset pain hypersensitivity following neonatal nerve injury","volume":"8","author":"Vega-Avelaira","year":"2012","journal-title":"Mol Pain"},{"key":"B73","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0165-3806(94)90163-5","article-title":"Dorsal root ganglion cell death and surviving cell numbers in relation to the development of sensory innervation in the rat hindlimb","volume":"82","author":"Coggeshall","year":"1994","journal-title":"Brain Res Dev Brain Res"},{"key":"B74","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1111\/j.1460-9568.1992.tb00115.x","article-title":"GAP-43 mRNA in rat spinal cord and dorsal root ganglia neurons: developmental changes and re-expression following peripheral nerve injury","volume":"4","author":"Chong","year":"1992","journal-title":"Eur J Neurosci"},{"key":"B75","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1002\/cne.10274","article-title":"Sensory neuron addition in juvenile rat: time course and specificity","volume":"449","author":"Farel","year":"2002","journal-title":"J Comp Neurol"},{"key":"B76","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/0304-3959(79)90123-4","article-title":"Deafferentation hypersensitivity in the rat after dorsal rhizotomy: a possible animal model of chronic pain","volume":"6","author":"Lombard","year":"1979","journal-title":"Pain"},{"key":"B77","doi-asserted-by":"publisher","first-page":"503","DOI":"10.1016\/S0304-3959(98)00243-7","article-title":"Behavioral manifestations of neuropathic pain and mechanical allodynia, and changes in spinal dorsal horn neurons, following L4-L6 dorsal root constriction in rats","volume":"80","author":"Tabo","year":"1999","journal-title":"Pain"},{"key":"B78","first-page":"25","article-title":"Self-mutilation in young rats after dorsal rhizotomy","volume":"26","author":"Vaculin","year":"2005","journal-title":"Neuro Endocrinol Lett"},{"key":"B79","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1038\/nn.4053","article-title":"Different immune cells mediate mechanical pain hypersensitivity in male and female mice","volume":"18","author":"Sorge","year":"2015","journal-title":"Nat Neurosci"},{"key":"B80","doi-asserted-by":"publisher","first-page":"15450","DOI":"10.1523\/JNEUROSCI.3859-11.2011","article-title":"Spinal cord toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice","volume":"31","author":"Sorge","year":"2011","journal-title":"J Neurosci"},{"key":"B81","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1016\/S0304-3940(00)00880-6","article-title":"Gender differences in rat neuropathic pain sensitivity is dependent on strain","volume":"282","author":"DeLeo","year":"2000","journal-title":"Neurosci Lett"},{"key":"B82","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.pain.2013.10.027","article-title":"Higher pain perception and lack of recovery from neuropathic pain in females: a behavioural, immunohistochemical, and proteomic investigation on sex-related differences in mice","volume":"155","author":"Vacca","year":"2014","journal-title":"Pain"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2016.00223\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T05:58:39Z","timestamp":1498370319000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2016.00223\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,15]]},"references-count":82,"URL":"https:\/\/doi.org\/10.3389\/fneur.2016.00223","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,15]]}}}