{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:20:21Z","timestamp":1787026821094,"version":"build-2736575974"},"reference-count":35,"publisher":"Frontiers Media SA","funder":[{"DOI":"10.13039\/100005191","name":"Craig H. Neilsen Foundation","doi-asserted-by":"publisher","award":["339705"],"award-info":[{"award-number":["339705"]}],"id":[{"id":"10.13039\/100005191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004856","name":"New York State Department of Health","doi-asserted-by":"publisher","award":["Contract No. DOH01-C30836GG-3450000"],"award-info":[{"award-number":["Contract No. DOH01-C30836GG-3450000"]}],"id":[{"id":"10.13039\/100004856","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2017.00050","type":"journal-article","created":{"date-parts":[[2017,2,19]],"date-time":"2017-02-19T22:33:00Z","timestamp":1487543580000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":26,"title":["Remodeling Brain Activity by Repetitive Cervicothoracic Transspinal Stimulation after Human Spinal Cord Injury"],"prefix":"10.3389","volume":"8","author":[{"given":"Lynda M.","family":"Murray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Knikou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2017,2,20]]},"reference":[{"issue":"4","key":"B1","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1093\/brain\/117.4.847","article-title":"Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex","volume":"117","author":"Pascual-Leone","year":"1994","journal-title":"Brain"},{"issue":"5","key":"B2","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1212\/WNL.48.5.1398","article-title":"Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation","volume":"48","author":"Chen","year":"1997","journal-title":"Neurology"},{"issue":"12","key":"B3","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1038\/nn.2691","article-title":"Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury","volume":"13","author":"Rosenzweig","year":"2010","journal-title":"Nat Neurosci"},{"issue":"1","key":"B4","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1038\/nm1682","article-title":"Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury","volume":"14","author":"Courtine","year":"2008","journal-title":"Nat Med"},{"issue":"1","key":"B5","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1682\/JRRD.2005.08.0140","article-title":"Review of physiological motor outcome measures in spinal cord injury using transcranial magnetic stimulation and spinal reflexes","volume":"44","author":"Ellaway","year":"2007","journal-title":"J Rehabil Res Dev"},{"issue":"1","key":"B6","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1093\/brain\/awh001","article-title":"Gradual loss of myelin and formation of an astrocytic scar during Wallerian degeneration in the human spinal cord","volume":"127","author":"Buss","year":"2004","journal-title":"Brain"},{"issue":"2","key":"B7","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/cne.21940","article-title":"Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys","volume":"513","author":"Rosenzweig","year":"2009","journal-title":"J Comp Neurol"},{"issue":"5","key":"B8","doi-asserted-by":"publisher","first-page":"781","DOI":"10.3171\/jns.1988.68.5.0781","article-title":"The effect of direct-current field on recovery from experimental spinal cord injury","volume":"68","author":"Fehlings","year":"1988","journal-title":"J Neurosurg"},{"issue":"8","key":"B9","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1016\/j.ejpain.2007.01.004","article-title":"Effects of spinal cord stimulation on cortical excitability in patients with chronic neuropathic pain: a pilot study","volume":"11","author":"Schlaier","year":"2007","journal-title":"Eur J Pain"},{"issue":"10","key":"B10","doi-asserted-by":"publisher","first-page":"e76940","DOI":"10.1371\/journal.pone.0076940","article-title":"Cervicothoracic multisegmental transpinal evoked potentials in humans","volume":"8","author":"Einhorn","year":"2013","journal-title":"PLoS One"},{"issue":"8","key":"B11","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1002\/bem.21808","article-title":"Neurophysiological characterization of transpinal evoked potentials in human leg muscles","volume":"34","author":"Knikou","year":"2013","journal-title":"Bioelectromagnetics"},{"issue":"3","key":"B12","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1002\/bem.21768","article-title":"Neurophysiological characteristics of human leg muscle action potentials evoked by transcutaneous magnetic stimulation of the spine","volume":"34","author":"Knikou","year":"2013","journal-title":"Bioelectromagnetics"},{"issue":"7","key":"B13","doi-asserted-by":"publisher","first-page":"e102313","DOI":"10.1371\/journal.pone.0102313","article-title":"Transpinal and transcortical stimulation alter corticospinal excitability and increase spinal output","volume":"9","author":"Knikou","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"B14","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1152\/jn.00259.2016","article-title":"Paired associative transspinal and transcortical stimulation produces plasticity in human cortical and spinal neuronal circuits","volume":"116","author":"Dixon","year":"2016","journal-title":"J Neurophysiol"},{"issue":"3","key":"B15","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1152\/jn.00449.2015","article-title":"Transspinal constant-current long-lasting stimulation: a new method to induce cortical and corticospinal plasticity","volume":"114","author":"Knikou","year":"2015","journal-title":"J Neurophysiol"},{"issue":"3","key":"B16","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1177\/1545968315591706","article-title":"Spinal rhythm generation by step-induced feedback and transcutaneous posterior root stimulation in complete spinal cord-injured individuals","volume":"30","author":"Minassian","year":"2016","journal-title":"Neurorehabil Neural Repair"},{"issue":"10","key":"B17","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1186\/1743-0003-10-108","article-title":"Sub-threshold spinal cord stimulation facilitates spontaneous motor activity in spinal rats","volume":"24","author":"Gad","year":"2013","journal-title":"J Neuroeng Rehabil"},{"issue":"2","key":"B18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1007\/s002210050341","article-title":"Magnetic transcranial stimulation at intensities below active motor threshold activates intracortical inhibitory circuits","volume":"119","author":"Di Lazzaro","year":"1998","journal-title":"Exp Brain Res"},{"key":"B19","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1113\/jphysiol.1993.sp019912","article-title":"Corticocortical inhibition in human motor cortex","volume":"471","author":"Kujirai","year":"1993","journal-title":"J Physiol"},{"issue":"3","key":"B20","doi-asserted-by":"publisher","first-page":"817","DOI":"10.1113\/jphysiol.1997.sp021905","article-title":"Intracortical facilitation and inhibition after transcranial magnetic stimulation in conscious humans","volume":"498","author":"Nakamura","year":"1997","journal-title":"J Physiol"},{"issue":"3","key":"B21","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1113\/jphysiol.1996.sp021734","article-title":"Interaction between intracortical inhibition and facilitation in human motor cortex","volume":"496","author":"Ziemann","year":"1996","journal-title":"J Physiol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.brainres.2014.02.017","article-title":"Influence of position and stimulation parameters on intracortical inhibition and facilitation in human tongue motor cortex","volume":"1557","author":"Kothari","year":"2014","journal-title":"Brain Res"},{"issue":"2","key":"B23","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1016\/0013-4694(78)90017-2","article-title":"Cumulative sum technique and its application to the analysis of peristimulus time histograms","volume":"45","author":"Ellaway","year":"1978","journal-title":"Electroencephalogr Clin Neurophysiol"},{"issue":"2","key":"B24","doi-asserted-by":"publisher","first-page":"1726","DOI":"10.1016\/j.clinph.2015.11.004","article-title":"Cortical activity after stimulation of the corticospinal tract in the spinal cord","volume":"127","author":"Costa","year":"2016","journal-title":"Clin Neurophysiol"},{"issue":"3","key":"B25","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1016\/S0304-3940(00)01125-3","article-title":"Loss of the muscle silent period evoked by transcranial magnetic stimulation of the motor cortex in patients with cervical cord lesions","volume":"286","author":"Shimizu","year":"2000","journal-title":"Neurosci Lett"},{"issue":"1","key":"B26","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.neulet.2008.01.038","article-title":"Motor cortex excitability changes following a lesion in the posterior columns of the cervical spinal cord","volume":"434","author":"Nardone","year":"2008","journal-title":"Neurosci Lett"},{"issue":"10","key":"B27","doi-asserted-by":"publisher","first-page":"990","DOI":"10.1002\/mus.880141010","article-title":"Estimate of motor conduction in human spinal cord: slowed conduction in spinal cord injury","volume":"14","author":"Chang","year":"1991","journal-title":"Muscle Nerve"},{"issue":"2","key":"B28","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1177\/1073858410397894","article-title":"Plasticity of cortical maps: multiple triggers for adaptive reorganization following brain damage and spinal cord injury","volume":"18","author":"Xerri","year":"2012","journal-title":"Neuroscientist"},{"issue":"3","key":"B29","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF01202383","article-title":"Transcranial magnetic stimulation: cortical motor maps in acute spinal cord injury","volume":"7","author":"Streletz","year":"1995","journal-title":"Brain Topogr"},{"issue":"17","key":"B30","doi-asserted-by":"crossref","first-page":"7000","DOI":"10.1523\/JNEUROSCI.18-17-07000.1998","article-title":"Mechanisms of deafferentation-induced plasticity in human motor cortex","volume":"18","author":"Ziemann","year":"1998","journal-title":"J Neurosci"},{"issue":"1","key":"B31","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1682\/JRRD.2005.10.0159","article-title":"Assessment of autonomic dysfunction following spinal cord injury: rationale for additions to international standards for neurological assessment","volume":"44","author":"Krassioukov","year":"2007","journal-title":"J Rehabil Res Dev"},{"issue":"1\u20132","key":"B32","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/S1566-0702(02)00207-2","article-title":"Sympathetic sudomotor skin activity in human after complete spinal cord injury","volume":"102","author":"Reitz","year":"2002","journal-title":"Auton Neurosci"},{"issue":"2","key":"B33","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1227\/00006123-199102000-00003","article-title":"Peripheral vasodilatation after spinal cord stimulation: animal studies of putative effector mechanisms","volume":"28","author":"Linderoth","year":"1991","journal-title":"Neurosurgery"},{"issue":"6","key":"B34","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1227\/00006123-199112000-00012","article-title":"Effects of sympathectomy on skin and muscle microcirculation during dorsal column stimulation: animal studies","volume":"29","author":"Linderoth","year":"1991","journal-title":"Neurosurgery"},{"issue":"4","key":"B35","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1227\/00006123-199410000-00018","article-title":"Sympathetic mediation of peripheral vasodilation induced by spinal cord stimulation: animal studies of the role of cholinergic and adrenergic receptor subtypes","volume":"35","author":"Linderoth","year":"1994","journal-title":"Neurosurgery"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2017.00050\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T17:33:18Z","timestamp":1568827998000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2017.00050\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,20]]},"references-count":35,"URL":"https:\/\/doi.org\/10.3389\/fneur.2017.00050","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,20]]}}}