{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T12:45:58Z","timestamp":1774442758538,"version":"3.50.1"},"reference-count":20,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2017.00241","type":"journal-article","created":{"date-parts":[[2017,6,2]],"date-time":"2017-06-02T03:59:17Z","timestamp":1496375957000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":23,"title":["Aging with Cerebral Small Vessel Disease and Dizziness: The Importance of Undiagnosed Peripheral Vestibular Disorders"],"prefix":"10.3389","volume":"8","author":[{"given":"Niccol\u00f2","family":"Cerchiai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelangelo","family":"Mancuso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Navari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Giannini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto Pietro","family":"Casani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2017,6,2]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"818","DOI":"10.1093\/gerona\/59.8.M818","article-title":"Cerebral white matter changes and geriatric syndromes: is there a link?","volume":"59","author":"Kuo","year":"2004","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"B2","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1111\/ggi.12665","article-title":"Impact of cerebral white matter changes on functionality in older adults: an overview of the LADIS Study results and future directions","volume":"15","author":"Pantoni","year":"2015","journal-title":"Geriatr Gerontol Int"},{"key":"B3","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1002\/ana.10294","article-title":"Periventricular cerebral white matter lesions predict rate of cognitive decline","volume":"52","author":"De Groot","year":"2002","journal-title":"Ann Neurol"},{"key":"B4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1161\/STROKEAHA.114.006704","article-title":"Association of postural instability with asymptomatic cerebrovascular damage and cognitive decline: the Japan Shimanami health promoting program study","volume":"46","author":"Tabara","year":"2015","journal-title":"Stroke"},{"key":"B5","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1212\/WNL.51.2.574","article-title":"Disequilibrium in older people: a prospective study","volume":"51","author":"Kerber","year":"1998","journal-title":"Neurology"},{"key":"B6","doi-asserted-by":"publisher","first-page":"2948","DOI":"10.1161\/STROKEAHA.114.006116","article-title":"White matter lesions are associated with hospital admissions because of hip-fractures and trauma after ischemic stroke","volume":"45","author":"Sibolt","year":"2014","journal-title":"Stroke"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1683","DOI":"10.1212\/WNL.43.9.1683","article-title":"Pathologic correlates of incidental MRI white matter signal hyperintensities","volume":"43","author":"Fazekas","year":"1993","journal-title":"Neurology"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e53455","DOI":"10.1371\/journal.pone.0053455","article-title":"Clinical symptoms and risk factors in cerebral microangiopathy patients","volume":"8","author":"Okroglic","year":"2013","journal-title":"PLoS One"},{"key":"B9","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1016\/j.jns.2015.09.006","article-title":"Are white matter abnormalities associated with \u201cunexplained dizziness\u201d?","volume":"358","author":"Ahmad","year":"2015","journal-title":"J Neurol Sci"},{"key":"B10","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1001\/archotol.1990.01870040046011","article-title":"The development of the Dizziness Handicap Inventory","volume":"116","author":"Jacobson","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"B11","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1196\/annals.1340.009","article-title":"Age-related changes in prefrontal white matter measured by diffusion tensor imaging","volume":"1064","author":"Salat","year":"2005","journal-title":"Ann N Y Acad Sci"},{"key":"B12","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3389\/fnagi.2015.00081","article-title":"Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles \u2013 a longitudinal MRI study of 76 middle-aged and older adults","volume":"7","author":"Vik","year":"2015","journal-title":"Front Aging Neurosci"},{"key":"B13","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1152\/physrev.2000.80.3.953","article-title":"Role of the basal ganglia in the control of purposive saccadic eye movements","volume":"80","author":"Hikosaka","year":"2000","journal-title":"Physiol Rev"},{"key":"B14","first-page":"509","article-title":"The effect of aging on visual-vestibular responses","volume":"9","author":"Baloh","year":"1993","journal-title":"Exp Brain Res"},{"key":"B15","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/S0957-4271(96)00137-1","article-title":"Aging and the human vestibular nucleus","volume":"7","author":"Lopez","year":"1997","journal-title":"J Vest Res"},{"key":"B16","doi-asserted-by":"publisher","first-page":"387","DOI":"10.3238\/arztebl.2015.0387","article-title":"Dizziness and unstable gait in old age","volume":"112","author":"Jahn","year":"2015","journal-title":"Dtsch Arztebl Int"},{"key":"B17","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1016\/S0194-5998(00)70187-2","article-title":"Unrecognized benign paroxysmal positional vertigo in elderly patients","volume":"122","author":"Oghalai","year":"2002","journal-title":"Otolaryngol Head Neck Surg"},{"key":"B18","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1007\/s00415-014-7275-1","article-title":"Do eye movement impairments in patients with small vessel cerebrovascular disease depend on lesion load or on cognitive deficits? A video-oculographic and MRI study","volume":"261","author":"Pinkhardt","year":"2014","journal-title":"J Neurol"},{"key":"B19","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1177\/0194599816689660","article-title":"Clinical practice guideline: benign paroxysmal positional vertigo (update)","volume":"156","author":"Bhattacharyya","year":"2017","journal-title":"Otolaryngol Head Neck Surg"},{"key":"B20","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1097\/WCO.0b013e32835c5ec4","article-title":"Vestibular rehabilitation","volume":"26","author":"Herdman","year":"2013","journal-title":"Curr Opin Neurol"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2017.00241\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T11:58:00Z","timestamp":1569412680000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2017.00241\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,2]]},"references-count":20,"alternative-id":["10.3389\/fneur.2017.00241"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2017.00241","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,2]]},"article-number":"241"}}