{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T11:50:46Z","timestamp":1792497046083,"version":"4.5.0"},"reference-count":76,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2018.00234","type":"journal-article","created":{"date-parts":[[2018,4,16]],"date-time":"2018-04-16T00:18:53Z","timestamp":1523837933000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":56,"title":["Association Between Peripheral Inflammation and DATSCAN Data of the Striatal Nuclei in Different Motor Subtypes of Parkinson Disease"],"prefix":"10.3389","volume":"9","author":[{"given":"Hossein","family":"Sanjari Moghaddam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzaneh","family":"Ghazi Sherbaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahtab","family":"Mojtahed Zadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Ashraf-Ganjouei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hadi","family":"Aarabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,4,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1186\/1471-2350-12-104","article-title":"Genome-wide association study identifies candidate genes for Parkinson\u2019s disease in an Ashkenazi Jewish population","volume":"12","author":"Liu","year":"2011","journal-title":"BMC Med Genet"},{"key":"B2","doi-asserted-by":"publisher","first-page":".e1707","DOI":"10.1016\/j.neurobiolaging.2012.10.019","article-title":"Supportive evidence for 11 loci from genome-wide association studies in Parkinson\u2019s disease","volume":"34","author":"Pihlstrom","year":"2013","journal-title":"Neurobiol Aging"},{"key":"B3","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1186\/1742-2094-11-52","article-title":"LRRK2 and neuroinflammation: partners in crime in Parkinson\u2019s disease?","volume":"11","author":"Russo","year":"2014","journal-title":"J Neuroinflammation"},{"key":"B4","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1001\/archneur.64.6.836","article-title":"Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease","volume":"64","author":"Wahner","year":"2007","journal-title":"Arch Neurol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1002\/mds.25035","article-title":"Association between Parkinson\u2019s disease and the HLA-DRB1 locus","volume":"27","author":"Ahmed","year":"2012","journal-title":"Mov Disord"},{"key":"B6","doi-asserted-by":"publisher","first-page":"Cd008454","DOI":"10.1002\/14651858.CD008454.pub2","article-title":"Non-steroidal anti-inflammatory drugs as disease-modifying agents for Parkinson\u2019s disease: evidence from observational studies","author":"Rees","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"B7","doi-asserted-by":"publisher","first-page":"1880","DOI":"10.1093\/brain\/awn101","article-title":"Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson\u2019s disease","volume":"131","author":"Pott Godoy","year":"2008","journal-title":"Brain"},{"key":"B8","doi-asserted-by":"publisher","first-page":"327089","DOI":"10.4061\/2011\/327089","article-title":"Lipopolysaccharide animal models for Parkinson\u2019s disease","volume":"2011","author":"Liu","year":"2011","journal-title":"Parkinsons Dis"},{"key":"B9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.parkreldis.2012.07.002","article-title":"In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson\u2019s disease","volume":"19","author":"Iannaccone","year":"2013","journal-title":"Parkinsonism Relat Disord"},{"key":"B10","doi-asserted-by":"publisher","first-page":"275178","DOI":"10.1155\/2014\/275178","article-title":"Immune responses in Parkinson\u2019s disease: interplay between central and peripheral immune systems","volume":"2014","author":"Su","year":"2014","journal-title":"Biomed Res Int"},{"key":"B11","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.neuroscience.2014.10.028","article-title":"Inflammation is genetically implicated in Parkinson\u2019s disease","volume":"302","author":"Dzamko","year":"2015","journal-title":"Neuroscience"},{"key":"B12","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1111\/j.1600-0404.1999.tb00721.x","article-title":"Association of circulating TNF-alpha and IL-6 with ageing and parkinsonism","volume":"100","author":"Dobbs","year":"1999","journal-title":"Acta Neurol Scand"},{"key":"B13","doi-asserted-by":"crossref","first-page":"725","DOI":"10.33588\/rn.4512.2007496","article-title":"[Immune factors or depression? Fatigue correlates in Parkinson\u2019s disease]","volume":"45","author":"Katsarou","year":"2007","journal-title":"Rev Neurol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.jneuroim.2009.08.001","article-title":"Increased serum levels of soluble tumor necrosis factor-alpha receptor-1 in patients with Parkinson\u2019s disease","volume":"216","author":"Scalzo","year":"2009","journal-title":"J Neuroimmunol"},{"key":"B15","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.cyto.2012.07.030","article-title":"Inflammatory cytokines and NT-proCNP in Parkinson\u2019s disease patients","volume":"60","author":"Koziorowski","year":"2012","journal-title":"Cytokine"},{"key":"B16","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1002\/mds.25752","article-title":"Plasma levels of soluble tumor necrosis factor receptors are associated with cognitive performance in Parkinson\u2019s disease","volume":"29","author":"Rocha","year":"2014","journal-title":"Mov Disord"},{"key":"B17","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/0304-3940(94)90508-8","article-title":"Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients","volume":"180","author":"Mogi","year":"1994","journal-title":"Neurosci Lett"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.2174\/138955709789055199","article-title":"Peripheral chemo-cytokine profiles in Alzheimer\u2019s and Parkinson\u2019s diseases","volume":"9","author":"Reale","year":"2009","journal-title":"Mini Rev Med Chem"},{"key":"B19","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.bbi.2008.07.003","article-title":"Peripheral cytokines profile in Parkinson\u2019s disease","volume":"23","author":"Reale","year":"2009","journal-title":"Brain Behav Immun"},{"key":"B20","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.neulet.2009.10.062","article-title":"Serum levels of interleukin-6 are elevated in patients with Parkinson\u2019s disease and correlate with physical performance","volume":"468","author":"Scalzo","year":"2010","journal-title":"Neurosci Lett"},{"key":"B21","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/S0165-5728(00)00422-7","article-title":"Lymphocyte populations in Parkinson\u2019s disease and in rat models of parkinsonism","volume":"113","author":"Bas","year":"2001","journal-title":"J Neuroimmunol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1016\/j.parkreldis.2005.07.005","article-title":"Alterations of T-lymphocyte populations in Parkinson disease","volume":"11","author":"Baba","year":"2005","journal-title":"Parkinsonism Relat Disord"},{"key":"B23","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1007\/s11481-012-9402-z","article-title":"CD4+ regulatory and effector\/memory T cell subsets profile motor dysfunction in Parkinson\u2019s disease","volume":"7","author":"Saunders","year":"2012","journal-title":"J Neuroimmune Pharmacol"},{"key":"B24","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.jneuroim.2012.07.015","article-title":"Reduced T helper and B lymphocytes in Parkinson\u2019s disease","volume":"252","author":"Stevens","year":"2012","journal-title":"J Neuroimmunol"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.nbd.2009.12.017","article-title":"Apoptosis of peripheral blood lymphocytes in Parkinson patients","volume":"38","author":"Calopa","year":"2010","journal-title":"Neurobiol Dis"},{"key":"B26","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1002\/ana.20369","article-title":"Blood\u2013brain barrier dysfunction in parkinsonian midbrain in vivo","volume":"57","author":"Kortekaas","year":"2005","journal-title":"Ann Neurol"},{"key":"B27","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1016\/s1474-4422(09)70062-6","article-title":"Neuroinflammation in Parkinson\u2019s disease: a target for neuroprotection?","volume":"8","author":"Hirsch","year":"2009","journal-title":"Lancet Neurol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1016\/s0140-6736(99)00641-8","article-title":"Blood vessels change in the mesencephalon of patients with Parkinson\u2019s disease","volume":"353","author":"Faucheux","year":"1999","journal-title":"Lancet"},{"key":"B29","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1111\/j.1750-3639.2012.00628.x","article-title":"Vascular degeneration in Parkinson\u2019s disease","volume":"23","author":"Guan","year":"2013","journal-title":"Brain Pathol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"S207","DOI":"10.1016\/s1353-8020(11)70064-5","article-title":"Neurodegeneration and inflammation in Parkinson\u2019s disease","volume":"18","author":"Phani","year":"2012","journal-title":"Parkinsonism Relat Disord"},{"key":"B31","doi-asserted-by":"publisher","first-page":"1567","DOI":"10.1111\/j.1471-4159.2007.04567.x","article-title":"Blood\u2013brain barrier disruption induces in vivo degeneration of nigral dopaminergic neurons","volume":"101","author":"Rite","year":"2007","journal-title":"J Neurochem"},{"key":"B32","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1016\/j.expneurol.2007.05.012","article-title":"Correlation between levels of pigment epithelium-derived factor and vascular endothelial growth factor in the striatum of patients with Parkinson\u2019s disease","volume":"206","author":"Yasuda","year":"2007","journal-title":"Exp Neurol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1111\/j.1478-3231.2011.02639.x","article-title":"Neutrophil to lymphocyte ratio: a new marker for predicting steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease","volume":"32","author":"Alkhouri","year":"2012","journal-title":"Liver Int"},{"key":"B34","doi-asserted-by":"publisher","first-page":"10.1","DOI":"10.1002\/0471142301.ns1001s49","article-title":"Assessment of Parkinson disease manifestations","volume":"10","author":"Perlmutter","year":"2009","journal-title":"Current protocols in neuroscience"},{"key":"B35","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1002\/mds.25383","article-title":"How to identify tremor dominant and postural instability\/gait difficulty groups with the movement disorder society unified Parkinson\u2019s disease rating scale: comparison with the unified Parkinson\u2019s disease rating scale","volume":"28","author":"Stebbins","year":"2013","journal-title":"Mov Disord"},{"key":"B36","first-page":"190","article-title":"123-I ioflupane SPECT measures of Parkinson disease progression in the Parkinson Progression Marker Initiative (PPMI) trial","volume":"54","author":"Seibyl","year":"2013","journal-title":"J Nuclear Med"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1611","DOI":"10.1001\/archneur.58.10.1611","article-title":"Functional decline in Parkinson disease","volume":"58","author":"Jankovic","year":"2001","journal-title":"Arch Neurol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1136\/jnnp.2005.081711","article-title":"Motor subtype and cognitive decline in Parkinson\u2019s disease, Parkinson\u2019s disease with dementia, and dementia with Lewy bodies","volume":"77","author":"Burn","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B39","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1016\/j.sleep.2007.02.005","article-title":"Relation between subtype of Parkinson\u2019s disease and REM sleep behavior disorder","volume":"8","author":"Kumru","year":"2007","journal-title":"Sleep Med"},{"key":"B40","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.parkreldis.2008.09.003","article-title":"The association between motor subtypes and psychopathology in Parkinson\u2019s disease","volume":"15","author":"Reijnders","year":"2009","journal-title":"Parkinsonism Relat Disord"},{"key":"B41","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1111\/j.1468-1331.2010.03167.x","article-title":"Differences in odor identification among clinical subtypes of Parkinson\u2019s disease","volume":"18","author":"Iijima","year":"2011","journal-title":"Eur J neurol"},{"key":"B42","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.jns.2018.01.013","article-title":"Comparison of clinical features among Parkinson\u2019s disease subtypes: a large retrospective study in a single center","volume":"386","author":"Konno","year":"2018","journal-title":"J Neurol Sci"},{"key":"B43","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1002\/mds.20897","article-title":"Changes in motor subtype and risk for incident dementia in Parkinson\u2019s disease","volume":"21","author":"Alves","year":"2006","journal-title":"Mov Disord"},{"key":"B44","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1097\/00005072-199111000-00006","article-title":"The neuropathologic basis of different clinical subgroups of Parkinson\u2019s disease","volume":"50","author":"Paulus","year":"1991","journal-title":"J Neuropathol Exp Neurol"},{"key":"B45","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1002\/mds.25220","article-title":"Neuropathological findings in benign tremulous parkinsonism","volume":"28","author":"Selikhova","year":"2013","journal-title":"Mov Disord"},{"key":"B46","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1212\/WNL.0b013e3181ae7af1","article-title":"Course in Parkinson disease subtypes a 39-year clinicopathologic study","volume":"73","author":"Rajput","year":"2009","journal-title":"Neurology"},{"key":"B47","doi-asserted-by":"publisher","first-page":"4716","DOI":"10.1002\/hbm.23697","article-title":"Structural connectivity differences in motor network between tremor-dominant and nontremor Parkinson\u2019s disease","volume":"38","author":"Barbagallo","year":"2017","journal-title":"Hum Brain Mapp"},{"key":"B48","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-3-7091-6360-3_1","article-title":"Post mortem studies in Parkinson\u2019s disease\u2014is it possible to detect brain areas for specific symptoms?","volume-title":"Diagnosis and Treatment of Parkinson\u2019s Disease\u2014State of the Art","author":"Jellinger","year":"1999"},{"key":"B49","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1002\/mds.23468","article-title":"Akinetic-rigid and tremor-dominant Parkinson\u2019s disease patients show different patterns of FP-CIT single photon emission computed tomography","volume":"26","author":"Eggers","year":"2011","journal-title":"Mov Disord"},{"key":"B50","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1016\/j.nicl.2016.01.010","article-title":"Relation of 18-F-Dopa PET with hypokinesia-rigidity, tremor and freezing in Parkinson\u2019s disease","volume":"11","author":"Pikstra","year":"2016","journal-title":"Neuroimage Clin"},{"key":"B51","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/0022-510X(95)00316-T","article-title":"Differences in the reduced 18F-Dopa uptakes of the caudate and the putamen in Parkinson\u2019s disease: correlations with the three main symptoms","volume":"136","author":"Otsuka","year":"1996","journal-title":"J Neurol Sci"},{"key":"B52","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1111\/j.1468-1331.2009.02898.x","article-title":"Differences in nigro-striatal impairment in clinical variants of early Parkinson\u2019s disease: evidence from a FP-CIT SPECT study","volume":"17","author":"Rossi","year":"2010","journal-title":"Eur J neurol"},{"key":"B53","doi-asserted-by":"publisher","first-page":"e46813","DOI":"10.1371\/journal.pone.0046813","article-title":"Parkinson subtypes progress differently in clinical course and imaging pattern","volume":"7","author":"Eggers","year":"2012","journal-title":"PLoS One"},{"key":"B54","doi-asserted-by":"publisher","first-page":"2112","DOI":"10.1007\/s00415-014-7459-8","article-title":"Dopamine transporter availability in motor subtypes of de novo drug-na\u00efve Parkinson\u2019s disease","volume":"261","author":"Moccia","year":"2014","journal-title":"J Neurol"},{"key":"B55","doi-asserted-by":"publisher","first-page":"2964","DOI":"10.1093\/brain\/awv215","article-title":"Clinical correlates of raphe serotonergic dysfunction in early Parkinson\u2019s disease","volume":"138","author":"Qamhawi","year":"2015","journal-title":"Brain"},{"key":"B56","doi-asserted-by":"publisher","first-page":"811","DOI":"10.1093\/brain\/awx376","article-title":"Progression of tremor in early stages of Parkinson\u2019s disease: a clinical and neuroimaging study","volume":"141","author":"Pasquini","year":"2018","journal-title":"Brain"},{"key":"B57","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1212\/01.wnl.0000285082.18969.3a","article-title":"Globus pallidus dopamine and Parkinson motor subtypes clinical and brain biochemical correlation","volume":"70","author":"Rajput","year":"2008","journal-title":"Neurology"},{"key":"B58","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1007\/s00415-012-6774-1","article-title":"Patients with rest-tremor and scans with ipsilateral dopaminergic deficit","volume":"260","author":"Aguirregomozcorta","year":"2013","journal-title":"J Neurol"},{"key":"B59","doi-asserted-by":"publisher","first-page":"2405","DOI":"10.1007\/s00415-013-7030-z","article-title":"Patients with Parkinson\u2019s disease and scans with (predominant) ipsilateral dopaminergic deficit","volume":"260","author":"Erro","year":"2013","journal-title":"J Neurol"},{"key":"B60","first-page":"S382","article-title":"The decreasing of dopamine-transporter uptake on the right ipsilateral side of tremor in a patient with Parkinson\u2019s disease","volume":"30","author":"Hoshiyama","year":"2015","journal-title":"Mov Disord"},{"key":"B61","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1002\/acn3.268","article-title":"Ipsilateral deficits of dopaminergic neurotransmission in Parkinson\u2019s disease","volume":"3","author":"Kaasinen","year":"2016","journal-title":"Ann clin transl neurol"},{"key":"B62","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1212\/WNL.51.3.803","article-title":"The metabolic anatomy of tremor in Parkinson\u2019s disease","volume":"51","author":"Antonini","year":"1998","journal-title":"Neurology"},{"key":"B63","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1002\/ana.22361","article-title":"Pallidal dysfunction drives a cerebellothalamic circuit into Parkinson tremor","volume":"69","author":"Helmich","year":"2011","journal-title":"Ann Neurol"},{"key":"B64","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/j.neuroscience.2010.12.060","article-title":"Differential involvement of striato- and cerebello-thalamo-cortical pathways in tremor-and akinetic\/rigid-predominant Parkinson\u2019s disease","volume":"177","author":"Lewis","year":"2011","journal-title":"Neuroscience"},{"key":"B65","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1177\/1545968317753075","article-title":"Differential white matter regional alterations in motor subtypes of early drug-naive Parkinson\u2019s disease patients","volume":"32","author":"Wen","year":"2018","journal-title":"Neurorehabil Neural Repair"},{"key":"B66","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1001\/jamaneurol.2013.6233","article-title":"Parkinson disease subtypes","volume":"71","author":"Thenganatt","year":"2014","journal-title":"JAMA Neurol"},{"key":"B67","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1002\/jcla.21791","article-title":"Neutrophil-to-lymphocyte ratio positively correlates to age in healthy population","volume":"29","author":"Li","year":"2015","journal-title":"J Clin Lab Anal"},{"key":"B68","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1007\/s10072-014-1976-1","article-title":"The increase of carcinoembryonic antigen (CEA), high-sensitivity C-reactive protein, and neutrophil\/lymphocyte ratio in Parkinson\u2019s disease","volume":"36","author":"Akil","year":"2015","journal-title":"Neurol Sci"},{"key":"B69","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1007\/s10072-016-2758-8","article-title":"Comparison of neutrophil\u2013lymphocyte ratio (NLR) in Parkinson\u2019s disease subtypes","volume":"38","author":"U\u00e7ar","year":"2017","journal-title":"Neurol Sci"},{"key":"B70","doi-asserted-by":"publisher","first-page":"33738","DOI":"10.1038\/srep33738","article-title":"Dopaminergic receptors on CD4+ T naive and memory lymphocytes correlate with motor impairment in patients with Parkinson\u2019s disease","volume":"6","author":"Kustrimovic","year":"2016","journal-title":"Sci Rep"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2017.10.050","article-title":"White matter changes correlates of peripheral neuroinflammation in patients with Parkinson\u2019s disease","author":"Haghshomar","year":"2017","journal-title":"Neuroscience"},{"key":"B72","doi-asserted-by":"publisher","first-page":"2283","DOI":"10.1093\/brain\/114.5.2283","article-title":"Ageing and Parkinson\u2019s disease: substantia nigra regional selectivity","volume":"114","author":"Fearnley","year":"1991","journal-title":"Brain"},{"key":"B73","doi-asserted-by":"publisher","first-page":"2089","DOI":"10.1212\/WNL.57.11.2089","article-title":"[123I] beta-CIT and SPECT assessment of progression in early and late Parkinson\u2019s disease","volume":"57","author":"Jennings","year":"2011","journal-title":"Neurology"},{"key":"B74","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1002\/mds.1139","article-title":"Rate of progression in Parkinson\u2019s disease: a 6-[18F] fluoro-L-dopa PET study","volume":"16","author":"Nurmi","year":"2001","journal-title":"Mov Disord"},{"key":"B75","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3233\/JPD-150769","article-title":"Retrograde axonal degeneration in Parkinson disease","volume":"6","author":"Tagliaferro","year":"2016","journal-title":"J Parkinson\u2019s dis"},{"key":"B76","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1016\/j.nicl.2017.03.011","article-title":"Axonal damage and loss of connectivity in nigrostriatal and mesolimbic dopamine pathways in early Parkinson\u2019s disease","volume":"14","author":"Caminiti","year":"2017","journal-title":"Neuroimage Clin"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2018.00234\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T13:49:26Z","timestamp":1751550566000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2018.00234\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,16]]},"references-count":76,"alternative-id":["10.3389\/fneur.2018.00234"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2018.00234","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/247080","asserted-by":"object"}]},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,16]]},"article-number":"234"}}