{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T00:02:08Z","timestamp":1785715328383,"version":"3.56.0"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T00:00:00Z","timestamp":1523318400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2018.00244","type":"journal-article","created":{"date-parts":[[2018,4,10]],"date-time":"2018-04-10T04:19:53Z","timestamp":1523333993000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":29,"title":["Hierarchical Cluster Analysis of Semicircular Canal and Otolith Deficits in Bilateral Vestibulopathy"],"prefix":"10.3389","volume":"9","author":[{"given":"Alexander A.","family":"Tarnutzer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Bockisch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Buffone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konrad P.","family":"Weber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,4,10]]},"reference":[{"key":"B1","first-page":"421","article-title":"The surgical treatment of M\u00e9ni\u00e8re\u2019s disease","volume":"72","author":"Dandy","year":"1941","journal-title":"Surg Gynecol Obstet"},{"key":"B2","doi-asserted-by":"publisher","first-page":"2732","DOI":"10.1093\/brain\/awh617","article-title":"Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans","volume":"128","author":"Brandt","year":"2005","journal-title":"Brain"},{"key":"B3","doi-asserted-by":"publisher","first-page":"1417","DOI":"10.1212\/WNL.0b013e3181a18652","article-title":"Horizontal head impulse test detects gentamicin vestibulotoxicity","volume":"72","author":"Weber","year":"2009","journal-title":"Neurology"},{"key":"B4","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1055\/s-0033-1354597","article-title":"Bilateral vestibular loss","volume":"33","author":"Hain","year":"2013","journal-title":"Semin Neurol"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1998","DOI":"10.1002\/hbm.23152","article-title":"Hippocampal gray matter volume in bilateral vestibular failure","volume":"37","author":"Gottlich","year":"2016","journal-title":"Hum Brain Mapp"},{"key":"B6","doi-asserted-by":"publisher","first-page":"177","DOI":"10.3233\/VES-170619","article-title":"Bilateral vestibulopathy: diagnostic criteria consensus document of the Classification Committee of the Barany Society","volume":"27","author":"Strupp","year":"2017","journal-title":"J Vestib Res"},{"key":"B7","doi-asserted-by":"publisher","first-page":"2791","DOI":"10.1016\/j.clinph.2016.05.005","article-title":"Disease-specific sparing of the anterior semicircular canals in bilateral vestibulopathy","volume":"127","author":"Tarnutzer","year":"2016","journal-title":"Clin Neurophysiol"},{"key":"B8","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1136\/jnnp.71.1.53","article-title":"Vestibular function in severe bilateral vestibulopathy","volume":"71","author":"Wiest","year":"2001","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B9","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1093\/brain\/120.6.1005","article-title":"Effect of otolith dysfunction. Impairment of visual acuity during linear head motion in labyrinthine defective subjects","volume":"120","author":"Lempert","year":"1997","journal-title":"Brain"},{"key":"B10","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.clinph.2009.10.016","article-title":"Vestibular evoked myogenic potentials: past, present and future","volume":"121","author":"Rosengren","year":"2010","journal-title":"Clin Neurophysiol"},{"key":"B11","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1007\/s11910-015-0548-y","article-title":"Clinical utility of ocular vestibular-evoked myogenic potentials (oVEMPs)","volume":"15","author":"Weber","year":"2015","journal-title":"Curr Neurol Neurosci Rep"},{"key":"B12","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1007\/s00415-008-0887-6","article-title":"Saccular function less affected than canal function in bilateral vestibulopathy","volume":"255","author":"Zingler","year":"2008","journal-title":"J Neurol"},{"key":"B13","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1007\/s00415-012-6724-y","article-title":"Semicircular canal, saccular and utricular function in patients with bilateral vestibulopathy: analysis based on etiology","volume":"260","author":"Agrawal","year":"2013","journal-title":"J Neurol"},{"key":"B14","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/0378-5955(94)90232-1","article-title":"Ototoxicity in vitro: effects of neomycin, gentamicin, dihydrostreptomycin, amikacin, spectinomycin, neamine, spermine and poly-L-lysine","volume":"73","author":"Kotecha","year":"1994","journal-title":"Hear Res"},{"key":"B15","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.clinph.2009.09.027","article-title":"A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli","volume":"121","author":"Curthoys","year":"2010","journal-title":"Clin Neurophysiol"},{"key":"B16","doi-asserted-by":"publisher","first-page":"974","DOI":"10.1097\/MAO.0b013e31828d676d","article-title":"Application of the video head impulse test to detect vertical semicircular canal dysfunction","volume":"34","author":"MacDougall","year":"2013","journal-title":"Otol Neurotol"},{"key":"B17","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1016\/j.clinph.2017.11.025","article-title":"Vestibulo-cochlear function in inflammatory neuropathies","volume":"129","author":"Blanquet","year":"2018","journal-title":"Clin Neurophysiol"},{"key":"B18","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.1212\/WNL.0b013e318295d72a","article-title":"Vestibular impairment in patients with Charcot-Marie-tooth disease","volume":"80","author":"Poretti","year":"2013","journal-title":"Neurology"},{"key":"B19","doi-asserted-by":"publisher","first-page":"3091","DOI":"10.1113\/jphysiol.2011.226225","article-title":"Single motor unit activity in human extraocular muscles during the vestibulo-ocular reflex","volume":"590","author":"Weber","year":"2012","journal-title":"J Physiol"},{"key":"B20","doi-asserted-by":"publisher","first-page":"268","DOI":"10.3766\/jaaa.25.3.6","article-title":"Amplitude normalization reduces cervical vestibular evoked myogenic potential (cVEMP) amplitude asymmetries in normal subjects: proof of concept","volume":"25","author":"McCaslin","year":"2014","journal-title":"J Am Acad Audiol"},{"key":"B21","doi-asserted-by":"publisher","first-page":"2198","DOI":"10.1016\/j.clinph.2014.12.027","article-title":"Effects of muscle contraction on cervical vestibular evoked myogenic potentials in normal subjects","volume":"126","author":"Rosengren","year":"2015","journal-title":"Clin Neurophysiol"},{"key":"B22","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1212\/WNL.0000000000002827","article-title":"A new saccadic indicator of peripheral vestibular function based on the video head impulse test","volume":"87","author":"MacDougall","year":"2016","journal-title":"Neurology"},{"key":"B23","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1016\/S0194-5998(95)70102-8","article-title":"Committee on Hearing and Equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere\u2019s disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc","volume":"113","author":"Monsell","year":"1995","journal-title":"Otolaryngol Head Neck Surg"},{"key":"B24","first-page":"1108","article-title":"Tentative standard procedures for evaluating the percentage of useful hearing loss in medicolegal cases","volume":"119","year":"1942","journal-title":"JAMA"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1903","DOI":"10.1212\/WNL.0b013e31821d746e","article-title":"Sensory neuropathy as part of the cerebellar ataxia neuropathy vestibular areflexia syndrome","volume":"76","author":"Szmulewicz","year":"2011","journal-title":"Neurology"},{"key":"B26","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1016\/j.ncl.2015.04.012","article-title":"Acute unilateral vestibulopathy","volume":"33","author":"Strupp","year":"2015","journal-title":"Neurol Clin"},{"key":"B27","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1177\/001316446002000104","article-title":"A coefficient for agreement for nominal scales","volume":"20","author":"Cohen","year":"1960","journal-title":"Educ Psychol Meas"},{"key":"B28","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.1126\/science.1151888","article-title":"Biochemistry. A postgenomic visual icon","volume":"319","author":"Weinstein","year":"2008","journal-title":"Science"},{"key":"B29","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1198\/tas.2009.0033","article-title":"The history of the cluster heat map","volume":"63","author":"Wilkinson","year":"2009","journal-title":"Am Stat"},{"key":"B30","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1007\/s004150050225","article-title":"Bilateral loss of vestibular function: clinical findings in 53 patients","volume":"245","author":"Rinne","year":"1998","journal-title":"J Neurol"},{"key":"B31","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1002\/ana.21105","article-title":"Causative factors and epidemiology of bilateral vestibulopathy in 255 patients","volume":"61","author":"Zingler","year":"2007","journal-title":"Ann Neurol"},{"key":"B32","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1097\/MAO.0b013e31821a3b7d","article-title":"Bilateral vestibulopathy: clinical characteristics and diagnostic criteria","volume":"32","author":"Kim","year":"2011","journal-title":"Otol Neurotol"},{"key":"B33","doi-asserted-by":"publisher","first-page":"26","DOI":"10.3389\/fneur.2016.00026","article-title":"Bilateral vestibular hypofunction: insights in etiologies, clinical subtypes, and diagnostics","volume":"7","author":"Lucieer","year":"2016","journal-title":"Front Neurol"},{"key":"B34","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3233\/VES-2007-17104","article-title":"Preserved vestibular evoked myogenic potentials (VEMP) in some patients with walking-induced oscillopsia due to bilateral vestibulopathy","volume":"17","author":"Brantberg","year":"2007","journal-title":"J Vestib Res"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1016\/j.clinph.2017.04.029","article-title":"Association of posterior semicircular canal hypofunction on video-head-impulse testing with other vestibulo-cochlear deficits","volume":"128","author":"Tarnutzer","year":"2017","journal-title":"Clin Neurophysiol"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1488","DOI":"10.1007\/s00415-009-5147-x","article-title":"Novel subtype of idiopathic bilateral vestibulopathy: bilateral absence of vestibular evoked myogenic potentials in the presence of normal caloric responses","volume":"256","author":"Fujimoto","year":"2009","journal-title":"J Neurol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1177\/000348941212100604","article-title":"Bilateral vestibulopathy with dissociated deficits in the superior and inferior vestibular systems","volume":"121","author":"Fujimoto","year":"2012","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"B38","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1136\/jnnp.2007.122952","article-title":"Follow-up of vestibular function in bilateral vestibulopathy","volume":"79","author":"Zingler","year":"2008","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B39","doi-asserted-by":"publisher","first-page":"154","DOI":"10.3389\/fneur.2015.00154","article-title":"The video head impulse test (vHIT) of semicircular canal function \u2013 age-dependent normative values of VOR gain in healthy subjects","volume":"6","author":"McGarvie","year":"2015","journal-title":"Front Neurol"},{"key":"B40","doi-asserted-by":"publisher","first-page":"2207","DOI":"10.1016\/j.clinph.2015.01.008","article-title":"Epidemiology of vestibular evoked myogenic potentials: data from the Baltimore Longitudinal Study of Aging","volume":"126","author":"Li","year":"2015","journal-title":"Clin Neurophysiol"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2018.00244\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,18]],"date-time":"2022-08-18T19:30:50Z","timestamp":1660851050000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/article\/10.3389\/fneur.2018.00244\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,10]]},"references-count":40,"alternative-id":["10.3389\/fneur.2018.00244"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2018.00244","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,10]]},"article-number":"244"}}