{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T01:21:28Z","timestamp":1768872088323,"version":"3.49.0"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T00:00:00Z","timestamp":1531785600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["G.0867.15"],"award-info":[{"award-number":["G.0867.15"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2018.00540","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T04:44:31Z","timestamp":1531802671000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":19,"title":["Adaptations to Postural Perturbations in Patients With Freezing of Gait"],"prefix":"10.3389","volume":"9","author":[{"given":"Esther M. J.","family":"Bekkers","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sam","family":"Van Rossom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elke","family":"Heremans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Dockx","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Surendar","family":"Devan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine M. P.","family":"Verschueren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Nieuwboer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2018,7,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"434683","DOI":"10.1155\/2015\/434683","article-title":"Balance dysfunction in Parkinson's disease","volume":"2015","author":"Rinalduzzi","year":"2015","journal-title":"Biomed Res Int."},{"key":"B2","doi-asserted-by":"publisher","first-page":"2250","DOI":"10.1093\/brain\/awh569","article-title":"A functional MRI study of automatic movements in patients with Parkinson's disease","volume":"128","author":"Wu","year":"2005","journal-title":"Brain"},{"key":"B3","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/0022-510X(92)90111-W","article-title":"Postural inflexibility in parkinsonian subjects","volume":"111","author":"Horak","year":"1992","journal-title":"J Neurol Sci."},{"key":"B4","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1002\/mds.870110506","article-title":"Influence of dopaminergic medication on automatic postural responses and balance impairment in Parkinson's disease","volume":"11","author":"Bloem","year":"1996","journal-title":"Mov Disord."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1245","DOI":"10.1136\/jnnp.2003.021147","article-title":"Postural abnormalities to multidirectional stance perturbations in Parkinson's disease","volume":"75","author":"Carpenter","year":"2004","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B6","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1152\/jn.00094.2003","article-title":"Postural muscle responses to multidirectional translations in patients with Parkinson's disease","volume":"91","author":"Dimitrova","year":"2004","journal-title":"J Neurophysiol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"2085","DOI":"10.1093\/brain\/awr131","article-title":"A block to pre-prepared movement in gait freezing, relieved by pedunculopontine nucleus stimulation","volume":"134","author":"Thevathasan","year":"2011","journal-title":"Brain"},{"key":"B8","doi-asserted-by":"publisher","first-page":"e0122064","DOI":"10.1371\/journal.pone.0122064","article-title":"StartReact effects support different pathophysiological mechanisms underlying freezing of gait and postural instability in Parkinson's disease","volume":"10","author":"Nonnekes","year":"2015","journal-title":"PLoS ONE"},{"key":"B9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.neurobiolaging.2016.10.024","article-title":"Individual differences in brainstem and basal ganglia structure predict postural control and balance loss in young and older adults","volume":"50","author":"Boisgontier","year":"2017","journal-title":"Neurobiol Aging"},{"key":"B10","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1002\/ana.24778","article-title":"Physiology of freezing of gait","volume":"80","author":"Snijders","year":"2016","journal-title":"Ann Neurol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1016\/S1474-4422(11)70143-0","article-title":"Freezing of gait: moving forward on a mysterious clinical phenomenon","volume":"10","author":"Nutt","year":"2011","journal-title":"Lancet Neurol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1016\/j.gaitpost.2015.06.007","article-title":"Balance differences in people with Parkinson disease with and without freezing of gait","volume":"42","author":"Duncan","year":"2015","journal-title":"Gait Posture"},{"key":"B13","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.gaitpost.2017.05.009","article-title":"Clinical balance scales indicate worse postural control in people with Parkinson's disease who exhibit freezing of gait compared to those who do not: A meta-analysis","volume":"56","author":"Bekkers","year":"2017","journal-title":"Gait Posture"},{"key":"B14","doi-asserted-by":"publisher","first-page":"700","DOI":"10.1016\/j.gaitpost.2013.10.003","article-title":"Postural inflexibility in PD: does it affect compensatory stepping?","volume":"39","author":"Smulders","year":"2014","journal-title":"Gait Posture"},{"key":"B15","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/j.neuroscience.2016.08.017","article-title":"Effects of freezing of gait on postural motor learning in people with Parkinson's disease","volume":"334","author":"Peterson","year":"2016","journal-title":"Neuroscience"},{"key":"B16","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.1093\/brain\/awh189","article-title":"Electromyographic profiles of gait prior to onset of freezing episodes in patients with Parkinson's disease","volume":"127","author":"Nieuwboer","year":"2004","journal-title":"Brain"},{"key":"B17","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1007\/s00415-006-0514-3","article-title":"Does freezing in Parkinson's disease change limb coordination?","volume":"254","author":"Nieuwboer","year":"2007","journal-title":"J Neurol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1177\/1545968314545175","article-title":"Motor switching and motor adaptation deficits contribute to freezing of gait in Parkinson's Disease","volume":"29","author":"Mohammadi","year":"2015","journal-title":"Neurorehab Neural Repair"},{"key":"B19","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.neuroscience.2017.09.017","article-title":"Freezing-related perception deficits of asymmetrical walking in Parkinson's disease","volume":"364","author":"Bekkers","year":"2017","journal-title":"Neuroscience"},{"key":"B20","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2147\/CIA.S3811","article-title":"Backward disequilibrium in elderly subjects","volume":"3","author":"Manckoundia","year":"2008","journal-title":"Clin Interv Aging"},{"key":"B21","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B22","doi-asserted-by":"publisher","first-page":"323","DOI":"10.2340\/16501977-0537","article-title":"Using psychometric techniques to improve the Balance Evaluation Systems Test: the mini-BESTest","volume":"42","author":"Franchignoni","year":"2010","journal-title":"J Rehabil Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.gaitpost.2010.02.014","article-title":"Solutions for representing the whole-body centre of mass in side cutting manoeuvres based on data that is typically available for lower limb kinematics","volume":"31","author":"Vanrenterghem","year":"2010","journal-title":"Gait Posture"},{"key":"B24","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/j.neuroscience.2010.03.068","article-title":"Dynamic posturography in Parkinson's disease: diagnostic utility of the \u201cfirst trial effect\u201d","volume":"168","author":"Visser","year":"2010","journal-title":"Neuroscience"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jbiomech.2004.03.025","article-title":"The condition for dynamic stability","volume":"38","author":"Hof","year":"2005","journal-title":"J Biomech."},{"key":"B26","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0165-0270(93)90152-H","article-title":"Correction for the influence of background muscle activity on stretch reflex amplitudes","volume":"46","author":"Bloem","year":"1993","journal-title":"J Neurosci Methods"},{"key":"B27","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1097\/NPT.0000000000000150","article-title":"Balance, body motion, and muscle activity after high-volume short-term dance-based rehabilitation in persons with Parkinson Disease: a pilot study","volume":"40","author":"McKay","year":"2016","journal-title":"J Neurol Phys Ther."},{"key":"B28","first-page":"135","article-title":"Quantitative assessment of co-contraction at the ankle joint in walking","volume":"25","author":"Falconer","year":"1985","journal-title":"Electromyogr Clin Neurophysiol."},{"key":"B29","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.expneurol.2004.12.008","article-title":"Direction-specific postural instability in subjects with Parkinson's disease","volume":"193","author":"Horak","year":"2005","journal-title":"Exp Neurol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.parkreldis.2015.12.011","article-title":"Postural control and freezing of gait in Parkinson's disease","volume":"24","author":"Schlenstedt","year":"2016","journal-title":"Parkinsonism Relat Disord."},{"key":"B31","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1007\/s00221-005-2346-2","article-title":"Can stooped posture explain multidirectional postural instability in patients with Parkinson's disease?","volume":"166","author":"Jacobs","year":"2005","journal-title":"Exp Brain Res."},{"key":"B32","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/j.neures.2004.06.015","article-title":"Role of basal ganglia-brainstem pathways in the control of motor behaviors","volume":"50","author":"Takakusaki","year":"2004","journal-title":"Neurosci Res."},{"key":"B33","doi-asserted-by":"publisher","first-page":"1","DOI":"10.14802\/jmd.16062","article-title":"Functional neuroanatomy for posture and gait control","volume":"10","author":"Takakusaki","year":"2017","journal-title":"J Mov Disord."},{"key":"B34","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1152\/jn.91013.2008","article-title":"The pontomedullary reticular formation contributes to the compensatory postural responses observed following removal of the support surface in the standing cat","volume":"101","author":"Stapley","year":"2009","journal-title":"J Neurophysiol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.gaitpost.2017.06.010","article-title":"Anticipatory postural adjustment patterns during gait initiation across the adult lifespan","volume":"57","author":"Lu","year":"2017","journal-title":"Gait Posture"},{"key":"B36","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1152\/jn.00813.2016","article-title":"Increased neuromuscular consistency in gait and balance after partnered, dance-based rehabilitation in Parkinson's disease","volume":"118","author":"Allen","year":"2017","journal-title":"J Neurophysiol"},{"key":"B37","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1037\/a0031278","article-title":"Impaired implicit sequence learning in Parkinson's disease patients with freezing of gait","volume":"27","author":"Vandenbossche","year":"2013","journal-title":"Neuropsychology"},{"key":"B38","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1152\/jn.1996.75.6.2380","article-title":"Effects of dopamine on postural control in Parkinsonian subjects: scaling, set, and tone","volume":"75","author":"Horak","year":"1996","journal-title":"J Neurophysiol."},{"key":"B39","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.bbr.2017.05.033","article-title":"Levodopa has primarily negative influences on postural control in patients with Parkinson's disease","volume":"331","author":"Bonnet","year":"2017","journal-title":"Behav Brain Res."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1002\/mds.26269","article-title":"Levodopa is a double-edged sword for balance and gait in people with Parkinson's Disease","volume":"30","author":"Curtze","year":"2015","journal-title":"Mov Disord."}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2018.00540\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T04:44:37Z","timestamp":1531802677000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2018.00540\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,17]]},"references-count":40,"alternative-id":["10.3389\/fneur.2018.00540"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2018.00540","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,17]]},"article-number":"540"}}