{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:47:14Z","timestamp":1785833234507,"version":"3.56.0"},"reference-count":32,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T00:00:00Z","timestamp":1542931200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2018.00993","type":"journal-article","created":{"date-parts":[[2018,11,23]],"date-time":"2018-11-23T05:49:47Z","timestamp":1542952187000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":42,"title":["Regional Cerebral Oximetry as an Indicator of Acute Brain Injury in Adults Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation\u2013A Prospective Pilot Study"],"prefix":"10.3389","volume":"9","author":[{"given":"Imad","family":"Khan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehboob","family":"Rehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunjan","family":"Parikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Zammit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeraj","family":"Badjatia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Herr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary","family":"Kon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Hogue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Mazzeffi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,11,23]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1097\/MAT.0000000000000160","article-title":"Extracorporeal membrane oxygenation use has increased by 433% in adults in the United States from 2006 to 2011","volume":"61","author":"Sauer","year":"2015","journal-title":"ASAIO J."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1389","DOI":"10.1097\/CCM.0000000000002502","article-title":"Neurologic injury in adults supported with veno-venous extracorporeal membrane oxygenation for respiratory failure: findings from the extracorporeal life support organization database","volume":"45","author":"Lorusso","year":"2017","journal-title":"Crit Care Med."},{"key":"B3","doi-asserted-by":"publisher","first-page":"e964","DOI":"10.1097\/CCM.0000000000001865","article-title":"In-Hospital neurologic complications in adult patients undergoing venoarterial extracorporeal membrane oxygenation: results from the extracorporeal life support organization registry","volume":"44","author":"Lorusso","year":"2016","journal-title":"Crit Care Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1097\/MAT.0000000000000128","article-title":"Cerebral tissue oxygenation during the initiation of venovenous ECMO","volume":"60","author":"Kredel","year":"2014","journal-title":"ASAIO J."},{"key":"B5","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1186\/cc11929","article-title":"Cerebral oximetry during extracorporeal cardiopulmonary resuscitation","volume":"17","author":"Taccone","year":"2013","journal-title":"Crit Care"},{"key":"B6","doi-asserted-by":"publisher","first-page":"E376","DOI":"10.1532\/HSF98.20041062","article-title":"Optimizing intraoperative cerebral oxygen delivery using noninvasive cerebral oximetry decreases the incidence of stroke for cardiac surgical patients","volume":"7","author":"Goldman","year":"2004","journal-title":"Heart Surg Forum"},{"key":"B7","doi-asserted-by":"publisher","first-page":"102","DOI":"10.4103\/0971-9784.109740","article-title":"Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery","volume":"16","author":"Mohandas","year":"2013","journal-title":"Ann Card Anaesth."},{"key":"B8","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.athoracsur.2008.08.070","article-title":"Cerebral oxygen desaturation predicts cognitive decline and longer hospital stay after cardiac surgery","volume":"87","author":"Slater","year":"2009","journal-title":"Ann Thorac Surg."},{"key":"B9","first-page":"2","volume-title":"Detection and Correction of Brain Oxygen Imbalance: Surgical and Critical Care Applications of the INVOS Cerebral Oximeter","author":"Edmonds","year":"2014"},{"key":"B10","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1111\/j.1525-1594.2012.01496.x","article-title":"Cerebral and lower limb near-infrared spectroscopy in adults on extracorporeal membrane oxygenation","volume":"36","author":"Wong","year":"2012","journal-title":"Artif Organs"},{"key":"B11","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1161\/01.CIR.84.2.960","article-title":"Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: the Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council","volume":"84","author":"Cummins","year":"1991","journal-title":"Circulation"},{"key":"B12","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jpeds.2003.11.006","article-title":"Oxygenation and hemodynamics in left and right cerebral hemispheres during induction of veno-arterial extracorporeal membrane oxygenation","volume":"144","author":"van Heijst","year":"2004","journal-title":"J Pediatr."},{"key":"B13","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1542\/peds.95.4.555","article-title":"Cerebral oxygenation and hemodynamics during induction of extracorporeal membrane oxygenation as investigated by near infrared spectrophotometry","volume":"95","author":"Liem","year":"1995","journal-title":"Pediatrics"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1117\/1.JBO.17.6.067008","article-title":"Multichannel near infrared spectroscopy indicates regional variations in cerebral autoregulation in infants supported on extracorporeal membrane oxygenation","author":"Papademetriou","year":"2012","journal-title":"J Biomed Opt."},{"key":"B15","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1038\/jp.2008.231","article-title":"Neonatal cerebral oximetry monitoring during ECMO cannulation","volume":"29","author":"Fenik","year":"2009","journal-title":"J Perinatol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1097\/01.PCC.0000200969.65438.83","article-title":"Cerebral oxygenation in neonatal and pediatric patients during veno-arterial extracorporeal life support","volume":"7","author":"Ejike","year":"2006","journal-title":"Pediatr Crit Care Med."},{"key":"B17","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.23736\/S0375-9393.17.11911-5","article-title":"Brain monitoring in adult and pediatric ECMO patients: the importance of early and late assessments","volume":"83","author":"Lorusso","year":"2017","journal-title":"Minerva Anestesiol."},{"key":"B18","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1177\/0885066616663649","article-title":"The correlation of two cerebral saturation monitors with jugular bulb oxygen saturation in children undergoing cardiopulmonary bypass for congenital heart surgery","volume":"32","author":"Naguib","year":"2017","journal-title":"J Intensive Care Med."},{"key":"B19","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1213\/00000539-199205000-00001","article-title":"The role of continuous jugular venous saturation monitoring during cardiac surgery with cardiopulmonary bypass","volume":"74","author":"Schell","year":"1992","journal-title":"Anesth Analg."},{"key":"B20","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1007\/s12028-018-0512-1","article-title":"Cerebral near-infrared spectroscopy in adult patients undergoing veno-arterial extracorporeal membrane oxygenation","volume":"29","author":"Pozzebon","year":"2018","journal-title":"Neurocrit Care"},{"key":"B21","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1186\/s13054-015-0997-3","article-title":"Disrupting differential hypoxia in peripheral veno-arterial extracorporeal membrane oxygenation","volume":"19","author":"Cove","year":"2015","journal-title":"Crit Care"},{"key":"B22","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/2049-6958-9-55","article-title":"Application of veno-arterial-venous extracorporeal membrane oxygenation in differential hypoxia","volume":"9","author":"Choi","year":"2014","journal-title":"Multidiscip Respir Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"2859","DOI":"10.1109\/IEMBS.2009.5333604","article-title":"Gender related differences in cerebral autoregulation in older healthy subjects","volume":"2009","author":"Deegan","year":"2009","journal-title":"Conf Proc IEEE Eng Med Biol Soc."},{"key":"B24","doi-asserted-by":"publisher","first-page":"e0135827","DOI":"10.1371\/journal.pone.0135827","article-title":"Effects of steroid hormones on sex differences in cerebral perfusion","volume":"10","author":"Ghisleni","year":"2015","journal-title":"PLoS ONE"},{"key":"B25","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s12028-012-9721-1","article-title":"Continuous cerebral blood flow autoregulation monitoring in patients undergoing liver transplantation","volume":"17","author":"Zheng","year":"2012","journal-title":"Neurocrit Care"},{"key":"B26","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1002\/hep.510250409","article-title":"Liver function, cerebral blood flow autoregulation, and hepatic encephalopathy in fulminant hepatic failure","volume":"25","author":"Strauss","year":"1997","journal-title":"Hepatology"},{"key":"B27","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1097\/00000539-200002000-00046","article-title":"Interference of cerebral near-infrared oximetry in patients with icterus","volume":"90","author":"Madsen","year":"2000","journal-title":"Anesth Analg."},{"key":"B28","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0300-9572(99)00060-X","article-title":"Prognostic significance of the difference between mixed venous and jugular bulb oxygen saturation in comatose patients resuscitated from a cardiac arrest","volume":"41","author":"Buunk","year":"1999","journal-title":"Resuscitation"},{"key":"B29","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1097\/00000542-200010000-00012","article-title":"Arterial and venous contributions to near-infrared cerebral oximetry","volume":"93","author":"Watzman","year":"2000","journal-title":"Anesthesiology"},{"key":"B30","doi-asserted-by":"publisher","first-page":"933","DOI":"10.1038\/jcbfm.2014.42","article-title":"Biomarkers for ischemic preconditioning: finding the responders","volume":"34","author":"Koch","year":"2014","journal-title":"J Cereb Blood Flow Metab."},{"key":"B31","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1177\/0267659113503681","article-title":"Limb ischemic preconditioning attenuates cerebral ischemic injury in arat model","volume":"29","author":"Wang","year":"2014","journal-title":"Perfusion"},{"key":"B32","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1016\/j.bpa.2014.09.002","article-title":"Cerebral and tissue oximetry","volume":"28","author":"Steppan","year":"2014","journal-title":"Best Pract Res Clin Anaesthesiol."}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2018.00993\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,6]],"date-time":"2022-09-06T19:19:16Z","timestamp":1662491956000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2018.00993\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,23]]},"references-count":32,"alternative-id":["10.3389\/fneur.2018.00993"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2018.00993","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,23]]},"article-number":"993"}}