{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:56:40Z","timestamp":1789477000936,"version":"build-2803163510"},"reference-count":55,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T00:00:00Z","timestamp":1544572800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2018.01036","type":"journal-article","created":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T05:09:20Z","timestamp":1544591360000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":92,"title":["Monitoring Motor Symptoms During Activities of Daily Living in Individuals With Parkinson's Disease"],"prefix":"10.3389","volume":"9","author":[{"given":"Jenna E.","family":"Thorp","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Gabriel","family":"Adamczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi-Lynn","family":"Ploeg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristen A.","family":"Pickett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2018,12,12]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1056\/NEJM199810153391607","article-title":"Parkinson's disease","volume":"339","author":"Lang","year":"1998","journal-title":"N Engl J Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"1529","DOI":"10.1212\/WNL.40.10.1529","article-title":"Variable expression of Parkinson's disease: a base-line analysis of the DAT ATOP cohort","volume":"40","author":"Jankovic","year":"1990","journal-title":"Neurology"},{"key":"B3","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1136\/jnnp.2007.131045","article-title":"Parkinson's disease: clinical features and diagnosis","volume":"79","author":"Jankovic","year":"2008","journal-title":"J Neurol Neurosurg Psychiatr."},{"key":"B4","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1002\/mds.10248","article-title":"Systematic evaluation of rating scales for impairment and disability in Parkinson's disease","volume":"17","author":"Ramaker","year":"2002","journal-title":"Movement Disorders"},{"key":"B5","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.1002\/mds.22340","article-title":"Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results","volume":"23","author":"Goetz","year":"2008","journal-title":"Movement Disorders"},{"key":"B6","doi-asserted-by":"publisher","first-page":"737","DOI":"10.1002\/1531-8257(199909)14:5<737::AID-MDS1005>3.0.CO;2-A","article-title":"A review of the assessment of dyskinesias","volume":"14","author":"Hoff","year":"1999","journal-title":"Movement Disorders"},{"key":"B7","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1186\/1743-0003-2-2","article-title":"Advances in wearable technology and applications in physical medicine and rehabilitation","volume":"2","author":"Bonato","year":"2005","journal-title":"J Neuro Eng Rehabil."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1002\/mds.26642","article-title":"Technology in Parkinson's disease: challenges and opportunities","volume":"31","author":"Espay","year":"2016","journal-title":"Movement Disorders"},{"key":"B9","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1016\/j.apmr.2015.12.029","article-title":"Randomized controlled trial of a home-based action observation intervention to improve walking in Parkinson's disease","volume":"97","author":"Jaywant","year":"2016","journal-title":"Arch Phys Med Rehabil."},{"key":"B10","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1097\/NPT.0b013e318254ba7a","article-title":"Capturing ambulatory activity decline in Parkinson's disease","volume":"36","author":"Cavanaugh","year":"2012","journal-title":"J Neurol Phys Ther."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.1002\/mds.26718","article-title":"Free-living monitoring of Parkinson's disease: lessons from the field","volume":"31","author":"Del Din","year":"2016","journal-title":"Movement Disorders"},{"key":"B12","doi-asserted-by":"publisher","first-page":"7772","DOI":"10.3390\/s100807772","article-title":"A review of accelerometry-based wearable motion detectors for physical activity monitoring","volume":"10","author":"Yang","year":"2010","journal-title":"Sensors"},{"key":"B13","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s10439-005-9068-2","article-title":"A review of approaches to mobility telemonitoring of the elderly in their living environment","volume":"34","author":"Scanaill","year":"2006","journal-title":"Ann Biomed Eng."},{"key":"B14","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1109\/MEMB.2003.1213632","article-title":"Online monitoring of dyskinesia in patients with Parkinson's disease","volume":"22","author":"Keijsers","year":"2003","journal-title":"IEEE Eng Med Biol Mag."},{"key":"B15","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1109\/MCG.2005.140","article-title":"Pedestrian tracking with shoe-mounted inertial sensors","volume":"25","author":"Foxlin","year":"2005","journal-title":"IEEE Comp Graph Appl."},{"key":"B16","doi-asserted-by":"crossref","DOI":"10.1109\/WPNC.2010.5649300","article-title":"Indoor pedestrian navigation using an INS\/EKF framework for yaw drift reduction and a foot-mounted IMU","volume-title":"2010 7th Workshop on Positioning Navigation and Communication (WPNC)","author":"Jim\u00e9nez","year":"2010"},{"key":"B17","unstructured":""},{"key":"B18","article-title":"Clinical feasibility of a wearable, conformable, sensor patch to monitor motor symptoms in Parkinson's disease","volume-title":"21st International Congress","author":"Boroojerdi","year":"2017"},{"key":"B19","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.cmpb.2012.10.016","article-title":"Automatic detection of freezing of gait events in patients with Parkinson's disease","volume":"110","author":"Tripoliti","year":"2013","journal-title":"Comp Methods Prog Biomed."},{"key":"B20","doi-asserted-by":"crossref","DOI":"10.1109\/ICIT.2000.854201","article-title":"Dynamic neural networks: an overview","volume-title":"2000 Proceedings of IEEE International Conference on Industrial Technology","author":"Sinha","year":"2000"},{"key":"B21","doi-asserted-by":"publisher","first-page":"67","DOI":"10.3233\/ida-2002-6105","article-title":"Dynamic support vector machines for non-stationary time series forecasting","volume":"6","author":"Cao","year":"2002","journal-title":"Intelligent Data Anal."},{"key":"B22","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1109\/tnsre.2014.2310904","article-title":"Dynamical learning and tracking of tremor and dyskinesia from wearable sensors","volume":"22","author":"Cole","year":"2014","journal-title":"IEEE Trans Neural Syst Rehabil Eng."},{"key":"B23","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/978-0-387-78189-1_8","article-title":"Linear Discriminant Analysis","volume-title":"Modern Multivariate Statistical Techniques","author":"Izenman","year":"2013"},{"key":"B24","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1002\/mds.26693","article-title":"Machine learning for large-scale wearable sensor data in Parkinson's disease: concepts, promises, pitfalls, and futures","volume":"31","author":"Kubota","year":"2016","journal-title":"Movement Disorders"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1002\/mds.25628","article-title":"Quantitative wearable sensors for objective assessment of Parkinson's disease","volume":"28","author":"Maetzler","year":"2013","journal-title":"Movement Disorders"},{"key":"B26","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/s12984-016-0136-7","article-title":"A systematic review of the characteristics and validity of monitoring technologies to assess Parkinson's disease","volume":"13","author":"Godinho","year":"2016","journal-title":"J Neuroeng Rehabil."},{"key":"B27","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1111\/ane.12248","article-title":"Technical and clinical view on ambulatory assessment in Parkinson's disease","volume":"130","author":"Hobert","year":"2014","journal-title":"Acta Neurol Scand."},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1093\/geront\/9.3_Part_1.179","article-title":"Assessment of older people: self-maintaining and instrumental activities of daily living","author":"Lawton","year":"1969","journal-title":"Gerontologist"},{"key":"B29","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1097\/00002826-200109000-00004","article-title":"Ambulatory objective assessment of tremor in Parkinson's disease","volume":"24","author":"Hoff","year":"2001","journal-title":"Clin Neuropharmacol."},{"key":"B30","doi-asserted-by":"crossref","DOI":"10.1109\/IEMBS.2011.6091198","article-title":"Resolving signal complexities for ambulatory monitoring of motor function in Parkinson's disease","volume-title":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","author":"Roy","year":"2011"},{"key":"B31","doi-asserted-by":"crossref","DOI":"10.1109\/IEMBS.2010.5627618","article-title":"Dynamic neural network detection of tremor and dyskinesia from wearable sensor data","volume-title":"2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","author":"Cole","year":"2010"},{"key":"B32","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1109\/tbme.2006.886670","article-title":"Quantification of tremor and bradykinesia in Parkinson's disease using a novel ambulatory monitoring system","volume":"54","author":"Salarian","year":"2007","journal-title":"IEEE Trans Biomed Eng."},{"key":"B33","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1097\/00004691-199805000-00007","article-title":"Ambulatory quantitative assessment of body position, bradykinesia, and hypokinesia in Parkinson's disease","volume":"15","author":"Dunnewold","year":"1998","journal-title":"J Clin Neurophysiol."},{"key":"B34","article-title":"Classification of movement states in Parkinson's disease using a wearable ambulatory monitor","volume-title":"AMIA Annual Symposium Proceedings","author":"Klapper","year":"2003"},{"key":"B35","doi-asserted-by":"crossref","DOI":"10.1109\/IEMBS.2007.4353793","article-title":"Analysis of feature space for monitoring persons with Parkinson's disease with application to a wireless wearable sensor system","volume-title":"2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS)","author":"Patel","year":"2007"},{"key":"B36","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.compbiomed.2017.03.020","article-title":"Estimating bradykinesia severity in Parkinson's disease by analysing gait through a waist-worn sensor","volume":"84","author":"Sam\u00e0","year":"2017","journal-title":"Comp Biol Med."},{"key":"B37","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1097\/00002826-200403000-00002","article-title":"Accuracy of objective ambulatory accelerometry in detecting motor complications in patients with Parkinson's disease","volume":"27","author":"Hoff","year":"2004","journal-title":"Clin Neuropharmacol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1002\/1531-8257(200101)16:1<58::AID-MDS1018>3.0.CO;2-9","article-title":"Accelerometric assessment of levodopa-induced dyskinesias in Parkinson's disease","volume":"16","author":"Hoff","year":"2001","journal-title":"Movement Disorders"},{"key":"B39","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1002\/1531-8257(200011)15:6<1104::AID-MDS1007>3.0.CO;2-E","article-title":"Detection and assessment of the severity of Levodopa-induced dyskinesia in patients with Parkinson's disease by neural networks","volume":"15","author":"Keijsers","year":"2000","journal-title":"Movement Disorders"},{"key":"B40","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1002\/mds.10310","article-title":"Automatic assessment of levodopa-induced dyskinesias in daily life by neural networks","volume":"18","author":"Keijsers","year":"2003","journal-title":"Movement Disorders"},{"key":"B41","doi-asserted-by":"crossref","DOI":"10.1109\/EMBC.2012.6346150","article-title":"Dyskinesia and motor state detection in Parkinson's disease patients with a single movement sensor","volume-title":"2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","author":"Sam\u00e0","year":"2012"},{"key":"B42","doi-asserted-by":"publisher","first-page":"e9","DOI":"10.2196\/mhealth.3321","article-title":"Validation of a portable device for mapping motor and gait disturbances in Parkinson's disease","volume":"3","author":"Rodr\u00edguez-Molinero","year":"2015","journal-title":"JMIR mHealth uHealth"},{"key":"B43","doi-asserted-by":"publisher","first-page":"609","DOI":"10.3233\/JPD-140348","article-title":"Motion sensor dyskinesia assessment during activities of daily living","volume":"4","author":"Pulliam","year":"2014","journal-title":"J Parkinson Dis."},{"key":"B44","doi-asserted-by":"publisher","first-page":"e8","DOI":"10.2196\/rehab.8335","article-title":"A kinematic sensor and algorithm to detect motor fluctuations in Parkinson's disease: validation study under real conditions of use","volume":"5","author":"Rodr\u00edguez-Molinero","year":"2018","journal-title":"JMIR Rehabil Assist Technol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/j.parkreldis.2012.03.001","article-title":"A comparison of clinical and objective measures of freezing of gait in Parkinson's disease","volume":"18","author":"Morris","year":"2012","journal-title":"Parkinson Relat Disorders"},{"key":"B46","doi-asserted-by":"publisher","first-page":"340","DOI":"10.1016\/j.jneumeth.2007.08.023","article-title":"Ambulatory monitoring of freezing of gait in Parkinson's disease","volume":"167","author":"Moore","year":"2008","journal-title":"J Neurosci Methods"},{"key":"B47","doi-asserted-by":"crossref","DOI":"10.4108\/ICST.BODYNETS2009.5852","article-title":"Online detection of freezing of gait in Parkinson's disease patients: a performance characterization","volume-title":"Proceedings of the Fourth International Conference on Body Area Networks","author":"B\u00e4chlin","year":"2009"},{"key":"B48","doi-asserted-by":"crossref","DOI":"10.1109\/IEMBS.2011.6091367","article-title":"Detecting freezing-of-gait during unscripted and unconstrained activity","volume-title":"2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","author":"Cole","year":"2011"},{"key":"B49","doi-asserted-by":"crossref","DOI":"10.1109\/ASCC.2015.7244608","article-title":"Freezing of Gait (FoG) detection for Parkinson's disease","volume-title":"2015 10th Asian IEEE Control Conference (ASCC)","author":"Tay","year":"2015"},{"key":"B50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.pmcj.2015.12.007","article-title":"The role of wrist-mounted inertial sensors in detecting gait freeze episodes in Parkinson's disease","volume":"33","author":"Mazilu","year":"2016","journal-title":"Pervasive Mob Comput."},{"key":"B51","doi-asserted-by":"publisher","first-page":"6819","DOI":"10.3390\/s140406819","article-title":"Detection of freezing of gait in Parkinson's disease: preliminary results","volume":"14","author":"Azevedo Coste","year":"2014","journal-title":"Sensors"},{"key":"B52","doi-asserted-by":"publisher","first-page":"e0171764","DOI":"10.1371\/journal.pone.0171764","article-title":"Home detection of freezing of gait using support vector machines through a single waist-worn triaxial accelerometer","volume":"12","author":"Rodr\u00edguez-Mart\u00edn","year":"2017","journal-title":"PLoS ONE"},{"key":"B53","doi-asserted-by":"publisher","first-page":"2152","DOI":"10.1109\/TBME.2017.2785625","article-title":"Modeling, detecting, and tracking freezing of gait in Parkinson's disease using inertial sensors","volume":"65","author":"Prateek","year":"2017","journal-title":"IEEE Trans Biomed Eng."},{"key":"B54","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.jns.2017.11.004","article-title":"Towards remote monitoring of Parkinson's disease tremor using wearable motion capture systems","volume":"384","author":"Delrobaei","year":"2018","journal-title":"J Neurol Sci."},{"key":"B55","doi-asserted-by":"publisher","first-page":"25055","DOI":"10.3390\/s151025055","article-title":"Quantitative assessment of parkinsonian tremor based on an inertial measurement unit","volume":"15","author":"Dai","year":"2015","journal-title":"Sensors"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2018.01036\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,12,12]],"date-time":"2018-12-12T05:09:25Z","timestamp":1544591365000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2018.01036\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,12]]},"references-count":55,"alternative-id":["10.3389\/fneur.2018.01036"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2018.01036","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,12,12]]},"article-number":"1036"}}