{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T19:18:08Z","timestamp":1793215088288,"version":"4.5.0"},"reference-count":38,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T00:00:00Z","timestamp":1585008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"DOI":"10.3389\/fneur.2020.00194","type":"journal-article","created":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T06:03:58Z","timestamp":1585029838000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":51,"title":["Clinical and MRI Features of Posterior Reversible Encephalopathy Syndrome With Atypical Regions: A Descriptive Study With a Large Sample Size"],"prefix":"10.3389","volume":"11","author":[{"given":"Kunhua","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dajing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanming","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2020,3,24]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1056\/NEJM199602223340803","article-title":"A reversible posterior leukoencephalopathy syndrome","volume":"334","author":"Hinchey","year":"1996","journal-title":"N Engl J Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1007\/s00415-011-6152-4","article-title":"The clinical and radiological spectrum of posterior reversible encephalopathy syndrome: the retrospective Berlin PRES study","volume":"259","author":"Liman","year":"2012","journal-title":"J Neurol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1097\/wco.0000000000000640","article-title":"Posterior reversible encephalopathy syndrome","volume":"32","author":"Liman","year":"2019","journal-title":"Curr Opin Neurol."},{"key":"B4","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1136\/jnnp-2017-316225","article-title":"Controversy of posterior reversible encephalopathy syndrome: what have we learnt in the last 20 years?","volume":"89","author":"Gao","year":"2018","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"B5","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1016\/S1474-4422(15)00111-8","article-title":"Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions","volume":"14","author":"Fugate","year":"2015","journal-title":"Lancet Neurol."},{"key":"B6","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1177\/1941874416688989","article-title":"Malignant posterior reversible encephalopathy syndrome\u2013an exacting challenge for neurocritical care physicians","volume":"7","author":"Magsi","year":"2017","journal-title":"Neurohospitalist."},{"key":"B7","doi-asserted-by":"publisher","first-page":"6897","DOI":"10.1007\/s12035-015-9560-0","article-title":"Posterior reversible encephalopathy syndrome after transplantation: a review","volume":"53","author":"Chen","year":"2016","journal-title":"Mol Neurobiol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/j.clinimag.2017.08.008","article-title":"The imaging spectrum of posterior reversible encephalopathy syndrome: a pictorial review","volume":"47","author":"Brady","year":"2018","journal-title":"Clin Imaging."},{"key":"B9","doi-asserted-by":"publisher","first-page":"1320","DOI":"10.3174\/ajnr.A0549","article-title":"Distinct imaging patterns and lesion distribution in posterior reversible encephalopathy syndrome","volume":"28","author":"Bartynski","year":"2007","journal-title":"Am J Neuroradiol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/j.carj.2016.08.005","article-title":"Posterior reversible encephalopathy syndrome: a review","volume":"68","author":"Shankar","year":"2017","journal-title":"Can Assoc Radiol J."},{"key":"B11","doi-asserted-by":"publisher","first-page":"843","DOI":"10.3389\/fneur.2018.00843","article-title":"Posterior reversible encephalopathy syndrome with isolated involving infratentorial structures","volume":"9","author":"Ou","year":"2018","journal-title":"Front Neurol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1080\/00207454.2018.1561452","article-title":"Isolated brainstem involvement in posterior reversible encephalopathy syndrome: a case report and review of the literature","volume":"129","author":"Liu","year":"2019","journal-title":"Int J Neurosci."},{"key":"B13","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.jns.2015.07.004","article-title":"Isolated cerebellar involvement in posterior reversible encephalopathy syndrome","volume":"357","author":"Li","year":"2015","journal-title":"J Neurol Sci."},{"key":"B14","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1177\/0883073816671237","article-title":"Posterior reversible encephalopathy syndrome with spinal cord involvement in children","volume":"32","author":"Chen","year":"2017","journal-title":"J Child Neurol."},{"key":"B15","doi-asserted-by":"publisher","first-page":"e3573","DOI":"10.7759\/cureus.3573","article-title":"Atypical variant of posterior reversible encephalopathy syndrome in the setting of renovascular hypertension: case report and review of literature","volume":"10","author":"Wittgrove","year":"2018","journal-title":"Cureus."},{"key":"B16","doi-asserted-by":"publisher","first-page":"631","DOI":"10.2214\/AJR.12.9677","article-title":"Central-variant posterior reversible encephalopathy syndrome: brainstem or basal ganglia involvement lacking cortical or subcortical cerebral edema","volume":"201","author":"McKinney","year":"2013","journal-title":"Am J Roentgenol."},{"key":"B17","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/j.ensci.2016.11.008","article-title":"Isolated pons involvement in posterior reversible encephalopathy syndrome: case report and review of the literature","volume":"6","author":"Ferrara","year":"2017","journal-title":"eNeurologicalSci"},{"key":"B18","doi-asserted-by":"publisher","first-page":"1873","DOI":"10.1007\/s10072-019-03914-3","article-title":"A study on clinical characteristics and the causes of missed diagnosis of reversible posterior leukoencephalopathy syndrome in eclampsia","volume":"40","author":"Shen","year":"2019","journal-title":"Neurol Sci."},{"key":"B19","doi-asserted-by":"publisher","first-page":"TD01","DOI":"10.7860\/JCDR\/2017\/23269.9682","article-title":"Central variant of posterior reversible encephalopathy syndrome\u2013a rare case report","volume":"11","author":"Srinivasan","year":"2017","journal-title":"J Clin Diagn Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.3389\/fneur.2019.01211","article-title":"Blood-brain barrier disruption as a potential target for therapy in posterior reversible encephalopathy syndrome: evidence from multimodal MRI in rats","volume":"10","author":"Wang","year":"2019","journal-title":"Front Neurol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1093\/neuros\/nyy240","article-title":"Posterior reversible encephalopathy syndrome as a complication of induced hypertension in subarachnoid hemorrhage: a case-control study","volume":"85","author":"Allen","year":"2019","journal-title":"Neurosurgery"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1177\/0284185113491252","article-title":"Can clinical and MRI findings predict the prognosis of variant and classical type of posterior reversible encephalopathy syndrome (PRES)?","volume":"54","author":"Moon","year":"2013","journal-title":"Acta Radiol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1055\/s-0031-1277990","article-title":"Posterior reversible encephalopathy syndrome: a review","volume":"31","author":"Feske","year":"2011","journal-title":"Semin Neurol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"830","DOI":"10.1016\/j.autrev.2015.05.006","article-title":"Posterior reversible encephalopathy syndrome\u2013insight into pathogenesis, clinical variants and treatment approaches","volume":"14","author":"Granata","year":"2015","journal-title":"Autoimmun Rev."},{"key":"B25","doi-asserted-by":"publisher","first-page":"1608","DOI":"10.1007\/s00415-016-8377-8","article-title":"Posterior reversible encephalopathy syndrome","volume":"264","author":"Fischer","year":"2017","journal-title":"J Neurol."},{"key":"B26","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/j.mehy.2014.02.022","article-title":"Posterior reversible encephalopathy syndrome: the endothelial hypotheses","volume":"82","author":"Marra","year":"2014","journal-title":"Med Hypotheses."},{"key":"B27","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.brainresbull.2017.03.012","article-title":"Immune system activation in the pathogenesis of posterior reversible encephalopathy syndrome","volume":"131","author":"Chen","year":"2017","journal-title":"Brain Res Bull."},{"key":"B28","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1016\/j.jns.2019.07.018","article-title":"Posterior reversible encephalopathy syndrome: a review with emphasis on neuroimaging characteristics","volume":"404","author":"Tetsuka","year":"2019","journal-title":"J Neurol Sci."},{"key":"B29","doi-asserted-by":"publisher","first-page":"904","DOI":"10.2214\/AJR.07.2024","article-title":"Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings","volume":"189","author":"McKinney","year":"2007","journal-title":"Am J Roentgenol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1007\/s00234-017-1815-1","article-title":"Imaging characteristics associated with clinical outcomes in posterior reversible encephalopathy syndrome","volume":"59","author":"Schweitzer","year":"2017","journal-title":"Neuroradiology"},{"key":"B31","doi-asserted-by":"publisher","first-page":"421","DOI":"10.21037\/qims.2018.05.07","article-title":"Risk factors for poor outcome in posterior reversible encephalopathy syndrome: systematic review and meta-analysis","volume":"8","author":"Chen","year":"2018","journal-title":"Quant Imaging Med Surg."},{"key":"B32","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.jns.2016.12.007","article-title":"Neuroimaging features in posterior reversible encephalopathy syndrome: a pictorial review","volume":"373","author":"Ollivier","year":"2017","journal-title":"J Neurol Sci."},{"key":"B33","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1148\/rg.272065155","article-title":"Patterns of contrast enhancement in the brain and meninges","volume":"27","author":"Smirniotopoulos","year":"2007","journal-title":"Radiographics."},{"key":"B34","doi-asserted-by":"publisher","first-page":"415","DOI":"10.3174\/ajnr.A4563","article-title":"Utility and significance of gadolinium-based contrast enhancement in posterior reversible encephalopathy syndrome","volume":"37","author":"Karia","year":"2016","journal-title":"Am J Neuroradiol."},{"key":"B35","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1007\/s00062-014-0293-7","article-title":"Posterior reversible encephalopathy syndrome: the spectrum of MR imaging patterns","volume":"25","author":"Kastrup","year":"2015","journal-title":"Clin Neuroradiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"896","DOI":"10.3174\/ajnr.A2886","article-title":"Detection of microhemorrhage in posterior reversible encephalopathy syndrome using susceptibility-weighted imaging","volume":"33","author":"McKinney","year":"2012","journal-title":"Am J Neuroradiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1007\/s00234-009-0632-6","article-title":"Imaging pattern of intracranial hemorrhage in the setting of posterior reversible encephalopathy syndrome","volume":"52","author":"Sharma","year":"2010","journal-title":"Neuroradiology"},{"key":"B38","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.3174\/ajnr.A1588","article-title":"Hemorrhage in posterior reversible encephalopathy syndrome: imaging and clinical features","volume":"30","author":"Hefzy","year":"2009","journal-title":"Am J Neuroradiol."}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2020.00194\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,24]],"date-time":"2020-03-24T06:04:00Z","timestamp":1585029840000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/article\/10.3389\/fneur.2020.00194\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,24]]},"references-count":38,"alternative-id":["10.3389\/fneur.2020.00194"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2020.00194","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,24]]},"article-number":"194"}}