{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T05:03:24Z","timestamp":1769835804269,"version":"3.49.0"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T00:00:00Z","timestamp":1623801600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>Carotid artery dissection (CAD) is the leading cause of ischemic stroke in young patients; however, the etiology and pathophysiology of CAD remain largely unknown. In our study, two types of dissections (length \u00d7 width: 1.5 cm \u00d7 1\/3 circumference of intima, Group I, <jats:italic>n<\/jats:italic> = 6; or 1.5 cm \u00d7 2\/3 circumference of intima, Group II, <jats:italic>n<\/jats:italic> = 6) were created between the media and intima. Ultrasound (within 2 h after dissection) showed a dissociated intima in the lumen and obstructed blood flow in the surgical area. Digital subtraction angiography (DSA, 72 h after dissection), magnetic resonance imaging (MRI, 72 h after dissection), and hematoxylin\u2013eosin (H&amp;amp;E, 7 days after dissection) staining confirmed stenosis (33.67 \u00b1 5.66%) in Group I and total occlusion in Group II. In 10 out of 12 swine, the CAD model was established using a detacher and balloon dilation, and morphological outcomes (stenosis or occlusion) after CAD were determined by the size of intimal incision.<\/jats:p>","DOI":"10.3389\/fneur.2021.669276","type":"journal-article","created":{"date-parts":[[2021,6,16]],"date-time":"2021-06-16T08:25:01Z","timestamp":1623831901000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Establishment of Carotid Artery Dissection and MRI Findings in a Swine Model"],"prefix":"10.3389","volume":"12","author":[{"given":"Jing","family":"Peng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desislava 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