{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T05:23:12Z","timestamp":1782364992571,"version":"3.54.5"},"reference-count":13,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T00:00:00Z","timestamp":1624579200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p><jats:bold>Introduction:<\/jats:bold> Diagnosis of Guillain Barre syndrome (GBS) is often made clinically. Certain patient and disease characteristics can cause delays in diagnosis and management.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> Observational retrospective study of forty-four patients diagnosed with GBS either clinically, cerebrospinal fluid analysis, and\/or by electro-diagnostic criteria at a teaching hospital (University of Missouri Hospital) in Columbia, Mid-Missouri between 2011 and 2017.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Patients with coexisting neurological conditions had statistically significant delay in diagnosis of GBS [Mean (SD); 13 \u00b1 5 vs. 9.39 \u00b1 4.7; <jats:italic>p<\/jats:italic> = 0.03]. Patients presenting with motor + symptoms (sensory and\/or autonomic, in addition to motor), compared to those with only motor symptoms had statistically significant delay in diagnosis of GBS [Mean (SD); 11.90 \u00b1 5 vs. 8.58 \u00b1 4; <jats:italic>p<\/jats:italic> = 0.04].<\/jats:p><jats:p><jats:bold>Discussion:<\/jats:bold> Presence of co-existing neurological conditions, and motor + symptoms can delay timely diagnosis and management of GBS.<\/jats:p>","DOI":"10.3389\/fneur.2021.684847","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T04:33:00Z","timestamp":1624595580000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Disease and Patient Characteristics Contributing to Diagnostic Delays in Patients With Guillain-Barr\u00e9 Syndrome"],"prefix":"10.3389","volume":"12","author":[{"given":"Chakrapani","family":"Pathikonda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nakul","family":"Katyal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naureen","family":"Narula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raghav","family":"Govindarajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,6,25]]},"reference":[{"key":"B1","first-page":"2405","article-title":"Guillain-Barr\u00e9 syndrome","volume":"69","author":"Newswanger","year":"2004","journal-title":"Am Fam Phys."},{"key":"B2","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.ncl.2013.01.005","article-title":"Guillain-Barr\u00e9 syndrome and 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