{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T13:23:35Z","timestamp":1793712215269,"version":"4.6.1"},"reference-count":251,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>Progressive supranuclear palsy (PSP) and corticobasal syndrome (CBS; the most common phenotype of corticobasal degeneration) are tauopathies with a relentless course, usually starting in the mid-60s and leading to death after an average of 7 years. There is as yet no specific or disease-modifying treatment. Clinical deficits in PSP are numerous, involve the entire neuraxis, and present as several discrete phenotypes. They center on rigidity, bradykinesia, postural instability, gait freezing, supranuclear ocular motor impairment, dysarthria, dysphagia, incontinence, sleep disorders, frontal cognitive dysfunction, and a variety of behavioral changes. CBS presents with prominent and usually asymmetric dystonia, apraxia, myoclonus, pyramidal signs, and cortical sensory loss. The symptoms and deficits of PSP and CBS are amenable to a variety of treatment strategies but most physicians, including many neurologists, are reluctant to care for patients with these conditions because of unfamiliarity with their multiplicity of interacting symptoms and deficits. CurePSP, the organization devoted to support, research, and education for PSP and CBS, created its CurePSP Centers of Care network in North America in 2017 to improve patient access to clinical expertise and develop collaborations. The directors of the 25 centers have created this consensus document outlining best practices in the management of PSP and CBS. They formed a writing committee for each of 12 sub-topics. A 4-member Steering Committee collated and edited the contributions. The result was returned to the entire cohort of authors for further comments, which were considered for incorporation by the Steering Committee. The authors hope that this publication will serve as a convenient guide for all clinicians caring for patients with PSP and CBS and that it will improve care for patients with these devastating but manageable disorders.<\/jats:p>","DOI":"10.3389\/fneur.2021.694872","type":"journal-article","created":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T18:14:54Z","timestamp":1625163294000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":76,"title":["Best Practices in the Clinical Management of Progressive Supranuclear Palsy and Corticobasal Syndrome: A Consensus Statement of the CurePSP Centers of Care"],"prefix":"10.3389","volume":"12","author":[{"given":"Brent","family":"Bluett","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander Y.","family":"Pantelyat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Litvan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farwa","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana","family":"Apetauerova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Bega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Bloom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Bower","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam L.","family":"Boxer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian L.","family":"Dale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Dhall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Duquette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert H.","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jori E.","family":"Fleisher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murray","family":"Grossman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Howell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana R.","family":"Kerwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Leegwater-Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Lepage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter Alexander","family":"Ljubenkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Mancini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolaus R.","family":"McFarland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Moretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Myrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pritika","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura S.","family":"Plummer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Rodriguez-Porcel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Sidiropoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Sklerov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard L.","family":"Sokol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Tuite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawren","family":"VandeVrede","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Marie A.","family":"Wills","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence I.","family":"Golbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2021,7,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1212\/WNL.46.4.922","article-title":"Accuracy of clinical criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome)","volume":"46","author":"Litvan","year":"1996","journal-title":"Neurology."},{"key":"B2","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1002\/mds.27034","article-title":"Which ante mortem clinical features predict progressive supranuclear palsy pathology?","volume":"32","author":"Respondek","year":"2017","journal-title":"Mov Disord."},{"key":"B3","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1002\/mds.26987","article-title":"Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria","volume":"32","author":"Hoglinger","year":"2017","journal-title":"Mov Disord."},{"key":"B4","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1002\/mds.10211","article-title":"Progressive supranuclear palsy diagnosis and confounding features: report on 16 autopsied cases","volume":"17","author":"Birdi","year":"2002","journal-title":"Mov Disord."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/npjparkd.2015.7","article-title":"Comparison of clinical features in pathologically confirmed PSP and MSA patients followed at a tertiary center","volume":"1","author":"Xie","year":"2015","journal-title":"NPJ Parkinsons Dis."},{"key":"B6","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1136\/jnnp.58.2.167","article-title":"Progressive supranuclear palsy: neuropathologically based diagnostic clinical criteria","volume":"58","author":"Collins","year":"1995","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.1001\/archneur.55.8.1099","article-title":"Pharmacological therapy in progressive supranuclear palsy","volume":"55","author":"Kompoliti","year":"1998","journal-title":"Arch Neurol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.parkreldis.2016.03.015","article-title":"Tremor in progressive supranuclear palsy","volume":"27","author":"Fujioka","year":"2016","journal-title":"Parkinsonism Relat Disord."},{"key":"B9","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1097\/00002826-199308000-00006","article-title":"Retrospective study of drug response in 87 patients with progressive supranuclear palsy","volume":"16","author":"Nieforth","year":"1993","journal-title":"Clin Neuropharmacol."},{"key":"B10","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1002\/ana.410130308","article-title":"Progressive supranuclear palsy: clinical features and response to treatment in 16 patients","volume":"13","author":"Jackson","year":"1983","journal-title":"Ann Neurol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1007\/s00415-016-8169-1","article-title":"PROSPERA: a randomized, controlled trial evaluating rasagiline in progressive supranuclear palsy","volume":"263","author":"Nuebling","year":"2016","journal-title":"J Neurol."},{"key":"B12","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1007\/s13760-018-0993-x","article-title":"Long-term treatment with rotigotine in drug-na\u00efve PSP patients","volume":"119","author":"Schirinzi","year":"2019","journal-title":"Acta Neurol Belg."},{"key":"B13","doi-asserted-by":"publisher","first-page":"873","DOI":"10.1212\/WNL.52.4.873","article-title":"Pramipexole in progressive supranuclear palsy","volume":"52","author":"Weiner","year":"1999","journal-title":"Neurology."},{"key":"B14","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1212\/WNL.33.4.505","article-title":"Controlled trial of pergolide mesylate in Parkinson's disease and progressive supranuclear palsy","volume":"33","author":"Jankovic","year":"1983","journal-title":"Neurology."},{"key":"B15","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1212\/WNL.57.3.467","article-title":"Randomized placebo-controlled trial of donepezil in patients with progressive supranuclear palsy","volume":"57","author":"Litvan","year":"2001","journal-title":"Neurology."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1111\/j.1532-5415.1996.tb02940.x","article-title":"Treatment of progressive supranuclear palsy with amitriptyline: therapeutic and toxic effects","volume":"44","author":"Engel","year":"1996","journal-title":"J Am Geriatr Soc."},{"key":"B17","doi-asserted-by":"publisher","first-page":"942","DOI":"10.1002\/mds.22023","article-title":"Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, placebo-controlled trial","volume":"23","author":"Stamelou","year":"2008","journal-title":"Mov Disord."},{"key":"B18","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1212\/NXI.0000000000000266","article-title":"CoQ10 in progressive supranuclear palsy: a randomized, placebo-controlled, double-blind trial","volume":"3","author":"Apetauerova","year":"2016","journal-title":"Neurol Neuroimmunol Neuroinflamm."},{"key":"B19","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1056\/NEJM199908123410721","article-title":"Zolpidem in progressive supranuclear palsy","volume":"341","author":"Daniele","year":"1999","journal-title":"N Engl J Med."},{"key":"B20","doi-asserted-by":"publisher","first-page":"2045","DOI":"10.1093\/brain\/awq123","article-title":"Does corticobasal degeneration exist? A clinicopathological re-evaluation","volume":"133","author":"Ling","year":"2010","journal-title":"Brain."},{"key":"B21","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1136\/jnnp.64.2.184","article-title":"Natural history and survival of 14 patients with corticobasal degeneration confirmed at postmortem examination","volume":"64","author":"Wenning","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"B22","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1001\/archneur.55.7.957","article-title":"Clinical presentation and pharmacological therapy in corticobasal degeneration","volume":"55","author":"Kompoliti","year":"1998","journal-title":"Arch Neurol."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1003","DOI":"10.2147\/NDT.S64015","article-title":"Rotigotine is safe and efficacious in atypical parkinsonism syndromes induced by both \u03b1-synucleinopathy and tauopathy","volume":"10","author":"Moretti","year":"2014","journal-title":"Neuropsychiatr Dis Treat."},{"key":"B24","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.parkreldis.2007.07.004","article-title":"Subthalamic stimulation improves levodopa responsive symptoms in a case of progressive supranuclear palsy","volume":"14","author":"Bergmann","year":"2008","journal-title":"Parkinsonism Relat Disord"},{"key":"B25","doi-asserted-by":"publisher","first-page":"2020","DOI":"10.1002\/mds.22706","article-title":"Implantation of the nucleus tegmenti pedunculopontini in a PSP-P patient: safe procedure, modest benefits","volume":"24","author":"Brusa","year":"2009","journal-title":"Mov Disord"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1002\/mds.25123","article-title":"Clinicopathological study in progressive supranuclear palsy with pedunculopontine stimulation","volume":"27","author":"Hazrati","year":"2012","journal-title":"Mov Disord"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1148","DOI":"10.1212\/WNL.0b013e3182886a76","article-title":"Pedunculopontine nucleus: functional organization and clinical implications","volume":"80","author":"Benarroch","year":"2013","journal-title":"Neurology"},{"key":"B28","doi-asserted-by":"publisher","first-page":"S416","DOI":"10.4103\/2152-7806.140208","article-title":"Long-term follow-up of deep brain stimulation of pedunculopontine nucleus in progressive supranuclear palsy: report of three cases","volume":"5","author":"Servello","year":"2014","journal-title":"Surg Neurol Int"},{"key":"B29","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1159\/000368702","article-title":"Bilateral pedunculopontine nucleus stimulation for progressive supranuclear palsy","volume":"93","author":"Doshi","year":"2015","journal-title":"Stereotact Funct Neurosurg"},{"key":"B30","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1007\/s00415-020-10233-7","article-title":"Spinal cord stimulation for gait dysfunction in progressive supranuclear palsy patients","volume":"268","author":"Samotus","year":"2021","journal-title":"J Neurol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1212\/01.WNL.0000052686.97625.27","article-title":"Progression of gait, speech and swallowing deficits in progressive supranuclear palsy","volume":"60","author":"Goetz","year":"2003","journal-title":"Neurology"},{"key":"B32","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1002\/mdc3.12879","article-title":"Falls in progressive supranuclear palsy","volume":"7","author":"Brown","year":"2020","journal-title":"Mov Disord Clin Pract"},{"key":"B33","doi-asserted-by":"publisher","first-page":"888","DOI":"10.1016\/j.parkreldis.2015.05.017","article-title":"Discriminating features of gait performance in progressive supranuclear palsy","volume":"21","author":"Amano","year":"2015","journal-title":"Parkinsonism Relat Disord"},{"key":"B34","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1136\/jnnp.2005.074070","article-title":"Predictors of falls and fractures in bradykinetic rigid syndromes: a retrospective study","volume":"77","author":"Williams","year":"2006","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e0173351","DOI":"10.1371\/journal.pone.0173351","article-title":"Impaired perception of surface tilt in progressive supranuclear palsy","volume":"12","author":"Dale","year":"2017","journal-title":"PLoS ONE"},{"key":"B36","doi-asserted-by":"publisher","first-page":"802","DOI":"10.1212\/01.wnl.0000304134.33380.1e","article-title":"Why do patients with PSP fall?: evidence for abnormal otolith responses","volume":"70","author":"Liao","year":"2008","journal-title":"Neurology"},{"key":"B37","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1093\/brain\/awv331","article-title":"Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson's disease","volume":"139","author":"Zhang","year":"2016","journal-title":"Brain"},{"key":"B38","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.parkreldis.2020.07.009","article-title":"Understanding the relationship between freezing of gait and other progressive supranuclear palsy features","volume":"78","author":"Rezvanian","year":"2020","journal-title":"Parkinsonism Relat Disord"},{"key":"B39","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.2522\/ptj.20070302","article-title":"Balance and eye movement training to improve gait in people with progressive supranuclear palsy: quasi-randomized clinical trial","volume":"88","author":"Zampieri","year":"2008","journal-title":"Phys Ther"},{"key":"B40","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1136\/pmj.76.896.333","article-title":"Progressive supranuclear palsy","volume":"76","author":"Rehman","year":"2000","journal-title":"Postgrad Med J"},{"key":"B41","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1093\/brain\/awm032","article-title":"A clinical rating scale for progressive supranuclear palsy","volume":"130","author":"Golbe","year":"2007","journal-title":"Brain."},{"key":"B42","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1007\/s40263-016-0347-2","article-title":"A review of treatment options for progressive supranuclear palsy","volume":"30","author":"Stamelou","year":"2016","journal-title":"CNS Drugs"},{"key":"B43","first-page":"254","article-title":"Traditional and experimental therapeutic approaches","volume-title":"Progressive Supranuclear Palsy: Clinical and Research Approaches","author":"Litvan","year":"1992"},{"key":"B44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1212\/WNL.47.1.1","article-title":"Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-SPSP international workshop","volume":"47","author":"Litvan","year":"1996","journal-title":"Neurology"},{"key":"B45","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S1353-8020(97)00022-9","article-title":"Amantadine effectiveness in multiple system atrophy and progressive supranuclear palsy","volume":"3","author":"Rajrut","year":"1997","journal-title":"Parkinsonism Relat Disord"},{"key":"B46","doi-asserted-by":"publisher","first-page":"986","DOI":"10.1212\/WNL.41.7.986","article-title":"Idazoxan treatment in progressive supranuclear palsy","volume":"41","author":"Ghika","year":"1991","journal-title":"Neurology"},{"key":"B47","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1002\/mds.870130411","article-title":"Efaroxan, an alpha-2 antagonist, in the treatment of progressive supranuclear palsy","volume":"13","author":"Rascol","year":"1998","journal-title":"Mov Disord"},{"key":"B48","doi-asserted-by":"publisher","first-page":"S83","DOI":"10.1002\/mds.20545","article-title":"Treatment of progressive supranuclear palsy and corticobasal degeneration","volume":"20","author":"Lang","year":"2005","journal-title":"Mov Disord"},{"key":"B49","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/BF02337027","article-title":"Treatment of progressive supranuclear palsy with methysergide. A clinical study","volume":"12","author":"Di Trapani","year":"1991","journal-title":"Ital J Neurol Sci."},{"key":"B50","doi-asserted-by":"publisher","first-page":"936","DOI":"10.1212\/WNL.35.6.936","article-title":"Methysergide in progressive supranuclear palsy","volume":"35","author":"Duncombe","year":"1985","journal-title":"Neurology"},{"key":"B51","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1177\/0269215519877235","article-title":"Exercise and physical activity for people with progressive supranuclear palsy: a systematic review","volume":"34","author":"Slade","year":"2020","journal-title":"Clin Rehabil"},{"key":"B52","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1093\/ptj\/82.5.485","article-title":"Supported treadmill training for gait and balance in a patient with progressive supranuclear palsy","volume":"82","author":"Suteerawattananon","year":"2002","journal-title":"Phys Ther"},{"key":"B53","doi-asserted-by":"publisher","first-page":"289","DOI":"10.2522\/ptj.20130052","article-title":"Long-term exercise training for an individual with mixed corticobasal degeneration and progressive supranuclear palsy features: 10-year case report follow-up","volume":"94","author":"Steffen","year":"2014","journal-title":"Phys Ther"},{"key":"B54","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1097\/CPT.0000000000000007","article-title":"Novel motor-assisted elliptical training intervention improves 6-minute walk test and oxygen cost for an individual with progressive supranuclear palsy","volume":"26","author":"Irons","year":"2015","journal-title":"Cardiopulm Phys Ther J."},{"key":"B55","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.pmrj.2017.12.011","article-title":"The role of rehabilitation in patients with progressive supranuclear palsy: a narrative review","volume":"10","author":"Intiso","year":"2018","journal-title":"PM&R"},{"key":"B56","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1007\/s11940-016-0422-5","article-title":"Progressive supranuclear palsy and corticobasal degeneration: pathophysiology and treatment options","volume":"18","author":"Lamb","year":"2016","journal-title":"Curr Treat Options Neurol."},{"key":"B57","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1517\/14656560903426171","article-title":"Treatment strategies for dystonia","volume":"11","author":"Cloud","year":"2010","journal-title":"Expert Opin Pharmacother"},{"key":"B58","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1007\/s11940-018-0488-3","article-title":"Botulinum toxin treatment of movement disorders","volume":"20","author":"Safarpour","year":"2018","journal-title":"Curr Treat Options Neurol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1002\/mds.1186","article-title":"Treatment of dystonic clenched fist with botulinum toxin","volume":"16","author":"Cordivari","year":"2001","journal-title":"Mov Disord"},{"key":"B60","doi-asserted-by":"publisher","first-page":"e01182","DOI":"10.1002\/brb3.1182","article-title":"Botulinum toxin for the treatment of dystonia and pain in corticobasal syndrome","volume":"9","author":"Unti","year":"2019","journal-title":"Brain Behav"},{"key":"B61","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.toxicon.2012.12.004","article-title":"Evidence-based review and assessment of botulinum neurotoxin for the treatment of movement disorders","volume":"67","author":"Hallett","year":"2013","journal-title":"Toxicon"},{"key":"B62","doi-asserted-by":"publisher","first-page":"1818","DOI":"10.1212\/WNL.0000000000002560","article-title":"Practice guideline update summary: botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache: Report of the guideline development subcommittee of the American Academy of Neurology","volume":"86","author":"Simpson","year":"2016","journal-title":"Neurology"},{"key":"B63","doi-asserted-by":"publisher","first-page":"379","DOI":"10.5334\/tohm.285","article-title":"Occurrence of dysphagia following botulinum toxin injection in Parkinsonism-related cervical dystonia: a retrospective study","volume":"6","author":"Patterson","year":"2016","journal-title":"Tremor Other Hyperkinet Mov."},{"key":"B64","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1080\/09593980701884816","article-title":"Physiotherapy in cervical dystonia: Six experimental single-case studies","volume":"24","author":"Zetterberg","year":"2008","journal-title":"Physiother Theory Pract."},{"key":"B65","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1177\/0269215512456221","article-title":"Active exercise for individuals with cervical dystonia: a pilot randomized controlled trial","volume":"27","author":"Boyce","year":"2013","journal-title":"Clin Rehabil"},{"key":"B66","doi-asserted-by":"publisher","first-page":"2187","DOI":"10.1002\/mds.22608","article-title":"Paramedical treatment in primary dystonia: a systematic review","volume":"24","author":"Delnooz","year":"2009","journal-title":"Mov Disord."},{"key":"B67","doi-asserted-by":"publisher","first-page":"2240","DOI":"10.1002\/mds.21145","article-title":"Botulinum toxin and neuromotor rehabilitation: an integrated approach to idiopathic cervical dystonia","volume":"21","author":"Tassorelli","year":"2006","journal-title":"Mov Disord"},{"key":"B68","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1002\/mds.20314","article-title":"Motor training as treatment in focal hand dystonia","volume":"20","author":"Zeuner","year":"2005","journal-title":"Mov Disord"},{"key":"B69","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1002\/mdc3.12574","article-title":"Systematic review of rehabilitation in focal dystonias: classification and recommendations","volume":"5","author":"Prudente","year":"2018","journal-title":"Mov Disord Clin Pract"},{"key":"B70","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1007\/s00702-019-01986-1","article-title":"Hand, foot, and spine deformities in Parkinsonian disorders","volume":"126","author":"Wijemanne","year":"2019","journal-title":"J Neural Transm"},{"key":"B71","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1016\/j.jpor.2017.09.004","article-title":"Sensory trick splint as a multimodal therapy for oromandibular dystonia","volume":"62","author":"Yoshida","year":"2018","journal-title":"J Prosthodont Res."},{"key":"B72","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1080\/13554794.2018.1499938","article-title":"Bilateral upper limb rehabilitation with videogame-based feedback in corticobasal degeneration: a case reports study","volume":"24","author":"Fusco","year":"2018","journal-title":"Neurocase"},{"key":"B73","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3233\/JPD-181523","article-title":"The neuro-ophthalmological assessment in Parkinson's disease","volume":"9","author":"Borm","year":"2019","journal-title":"J. Parkinsons Dis."},{"key":"B74","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1002\/mds.870040402","article-title":"Eyelid movement abnormalities in progressive supranuclear palsy","volume":"4","author":"Golbe","year":"1989","journal-title":"Mov Disord"},{"key":"B75","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s40035-019-0160-1","article-title":"How to spot ocular abnormalities in progressive supranuclear palsy? A practical review","volume":"8","author":"Phokaewvarangkul","year":"2019","journal-title":"Transl Neurodegen"},{"key":"B76","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1002\/ana.410350408","article-title":"Eye movements in Parkinsonian syndromes","volume":"35","author":"Vidailhet","year":"1994","journal-title":"Ann Neurol."},{"key":"B77","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1111\/cxo.12429","article-title":"Visual signs and symptoms of corticobasal degeneration","volume":"99","author":"Armstrong","year":"2016","journal-title":"Clin Exp Optom"},{"key":"B78","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.neucli.2004.01.002","article-title":"Eyelid movements in health and disease. the supranuclear impairment of the palpebral motility","volume":"34","author":"Esteban","year":"2004","journal-title":"Clin Neurophysiol"},{"key":"B79","doi-asserted-by":"publisher","first-page":"162","DOI":"10.22336\/rjo.2018.24","article-title":"Injecting botulinum toxin into the treatment of blepharospasm","volume":"62","author":"Popescu","year":"2018","journal-title":"Rom J Ophthal"},{"key":"B80","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1002\/mds.870090605","article-title":"\u201cApraxia of lid opening,\" a focal eyelid dystonia: Clinical study of 32 patients","volume":"9","author":"Krack","year":"1994","journal-title":"Mov Disord."},{"key":"B81","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1007\/BF00941758","article-title":"Comparison of two botulinum-toxin preparations in the treatment of essential blepharospasm","volume":"235","author":"Nussgens","year":"1997","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"B82","doi-asserted-by":"publisher","first-page":"CD004314","DOI":"10.1002\/14651858.CD004314.pub3","article-title":"Botulinum toxin type A versus botulinum toxin type B for cervical dystonia","volume":"10","author":"Duarte","year":"2016","journal-title":"Cochrane Database Syst Rev."},{"key":"B83","doi-asserted-by":"publisher","first-page":"S129","DOI":"10.1002\/mds.20066","article-title":"Clinical comparability of marketed formulations of botulinum toxin","volume":"19","author":"Sampaio","year":"2004","journal-title":"Mov Disord"},{"key":"B84","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1111\/j.1468-1331.2006.01441.x","article-title":"Botulinum toxin in blepharospasm and oromandibular dystonia: comparing different botulinum toxin preparations","volume":"13","author":"Bhidayasiri","year":"2006","journal-title":"Eur J Neurol"},{"key":"B85","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1212\/WNL.46.1.26","article-title":"Botulinum toxin therapy, immunologic resistance, and problems with available materials","volume":"46","author":"Borodic","year":"1996","journal-title":"Neurology"},{"key":"B86","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1111\/j.1468-1331.2010.03042.x","article-title":"EFNS guidelines on diagnosis and treatment of primary dystonias","volume":"18","author":"Albanese","year":"2011","journal-title":"Eur J Neurol"},{"key":"B87","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1111\/ene.13488","article-title":"Quality and reporting of guidelines on the diagnosis and management of dystonia","volume":"25","author":"Tam\u00e1s","year":"2018","journal-title":"Eur J Neurol"},{"key":"B88","doi-asserted-by":"publisher","first-page":"22","DOI":"10.14802\/jmd.18010","article-title":"Sensory trick frames: a new device for blepharospasm patients","volume":"12","author":"Lorenzano","year":"2019","journal-title":"J Mov Disord"},{"key":"B89","doi-asserted-by":"publisher","first-page":"S27","DOI":"10.1016\/j.ophtha.2017.07.022","article-title":"Update in current diagnostics and therapeutics of dry eye disease","volume":"124","author":"Thulasi","year":"2017","journal-title":"Ophthalmology"},{"key":"B90","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1056\/NEJMra1407936","article-title":"Dry eye","volume":"378","author":"Clayton","year":"2018","journal-title":"N Engl J Med"},{"key":"B91","doi-asserted-by":"publisher","first-page":"736","DOI":"10.1016\/j.molmed.2015.10.001","article-title":"Lipid-based therapy for ocular surface inflammation and disease","volume":"21","author":"Lim","year":"2015","journal-title":"Trends Mol Med"},{"key":"B92","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1016\/j.rdc.2008.08.008","article-title":"Treatment of dry eye disease by the non-ophthalmologist","volume":"34","author":"Foulks","year":"2008","journal-title":"Rheum Dis Clin North Am."},{"key":"B93","doi-asserted-by":"publisher","first-page":"1419","DOI":"10.2147\/OPTH.S65263","article-title":"Artificial tears potpourri: a literature review","volume":"8","author":"Moshirfar","year":"2014","journal-title":"Clin Ophthalmol"},{"key":"B94","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1097\/ICU.0000000000000569","article-title":"Advances in dry eye disease treatment","volume":"30","author":"O'Neil","year":"2019","journal-title":"Curr Opin Ophthalmol"},{"key":"B95","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1038\/eye.2017.289","article-title":"Assessment and management of dry eye disease","volume":"32","author":"Buckley","year":"2018","journal-title":"Eye"},{"key":"B96","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/j.apmr.2008.07.024","article-title":"Improvement of gaze control after balance and eye movement training in patients with progressive supranuclear palsy: a quasi-randomized controlled trial","volume":"90","author":"Zampieri","year":"2009","journal-title":"Arch Phys Med Rehabil"},{"key":"B97","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1136\/jnnp-2018-319374","article-title":"Association of autonomic symptoms with disease progression and survival in progressive supranuclear palsy","volume":"90","author":"Oliveira","year":"2019","journal-title":"J Neurol Neurosurg Psychiatry."},{"key":"B98","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s00415-009-5255-7","article-title":"Non-motor symptoms in atypical and secondary Parkinsonism: the PRIAMO study","volume":"257","author":"Colosimo","year":"2010","journal-title":"J Neurol"},{"key":"B99","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1046\/j.0305-1846.2001.00374.x","article-title":"Progressive supranuclear palsy: neuronal and glial cytoskeletal pathology in the higher order processing autonomic nuclei of the lower brainstem","volume":"28","author":"R\u00fcb","year":"2002","journal-title":"Neuropathol Appl Neurobiol"},{"key":"B100","doi-asserted-by":"publisher","first-page":"901","DOI":"10.1002\/mds.23587","article-title":"Hypodipsia discriminates progressive supranuclear palsy from other Parkinsonian syndromes","volume":"26","author":"Stamelou","year":"2011","journal-title":"Mov Disord"},{"key":"B101","doi-asserted-by":"publisher","first-page":"920","DOI":"10.3109\/00365529709011203","article-title":"Stool form scale as a useful guide to intestinal transit time","volume":"32","author":"Lewis","year":"1997","journal-title":"Scand J Gastroenterol"},{"key":"B102","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1002\/mds.870120617","article-title":"Constipation in Parkinson's disease: objective assessment and response to psyllium","volume":"12","author":"Ashraf","year":"1997","journal-title":"Mov Disord"},{"key":"B103","doi-asserted-by":"publisher","first-page":"CD002115","DOI":"10.1002\/14651858.CD002115.pub5","article-title":"Management of faecal incontinence and constipation in adults with central neurological diseases","volume":"13","author":"Coggrave","year":"2014","journal-title":"Cochrane Database Syst Rev."},{"key":"B104","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1002\/mds.21243","article-title":"Macrogol for the treatment of constipation in Parkinson's disease. A randomized placebo-controlled study","volume":"22","author":"Zangaglia","year":"2007","journal-title":"Mov Disord"},{"key":"B105","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1002\/mdc3.12577","article-title":"Linaclotide and prucalopride for management of constipation in patients with Parkinsonism","volume":"5","author":"Freitas","year":"2018","journal-title":"Mov Dis Clin Pract"},{"key":"B106","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1002\/mds.22289","article-title":"Autonomic dysfunction in patients with progressive supranuclear palsy","volume":"23","author":"Schmidt","year":"2008","journal-title":"Mov Disord"},{"key":"B107","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1007\/s00702-009-0313-y","article-title":"Comprehensive autonomic assessment does not differentiate between Parkinson's disease, multiple system atrophy and progressive supranuclear palsy","volume":"117","author":"Reimann","year":"2010","journal-title":"J Neural Transm"},{"key":"B108","doi-asserted-by":"publisher","first-page":"e0149278","DOI":"10.1371\/journal.pone.0149278","article-title":"Urinary dysfunction in progressive supranuclear palsy compared with other Parkinsonian disorders","volume":"11","author":"Yamamoto","year":"2016","journal-title":"PLoS ONE"},{"key":"B109","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1002\/nau.23496","article-title":"Neurogenic bladder in progressive supranuclear palsy: a comparison with Parkinson's disease and multiple system atrophy","volume":"37","author":"Kim","year":"2018","journal-title":"Neurourol Urodyn"},{"key":"B110","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1002\/1531-8249(200007)48:1<97::AID-ANA14>3.0.CO;2-Z","article-title":"Neuronal loss in Onuf's nucleus in three patients with progressive supranuclear palsy","volume":"48","author":"Scaravilli","year":"2000","journal-title":"Ann Neurol"},{"key":"B111","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s11940-016-0427-0","article-title":"Treatment options for urogenital dysfunction in Parkinson's disease","volume":"18","author":"Batla","year":"2016","journal-title":"Curr Treat Options Neurol."},{"key":"B112","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1002\/mdc3.12279","article-title":"Nocturia in patients with Parkinson's disease","volume":"3","author":"Smith","year":"2016","journal-title":"Mov Disord Clin Pract"},{"key":"B113","doi-asserted-by":"publisher","first-page":"432","DOI":"10.4103\/aian.AIAN_6_18","article-title":"Urinary symptoms in patients with Parkinson's disease and progressive supranuclear palsy: urodynamic findings and management of bladder dysfunction","volume":"22","author":"Gupta","year":"2019","journal-title":"Ann Ind Acad Neurol"},{"key":"B114","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/S0022-5347(05)67961-X","article-title":"Nocturia","volume":"163","author":"Weiss","year":"2000","journal-title":"J Urol"},{"key":"B115","doi-asserted-by":"publisher","first-page":"e1427","DOI":"10.1212\/WNL.0000000000008931","article-title":"Bladder training for urinary tract symptoms in Parkinson disease: a randomized controlled trial","volume":"94","author":"McDonald","year":"2020","journal-title":"Neurology"},{"key":"B116","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1212\/WNL.0b013e318219fab3","article-title":"Behavioral therapy to treat urinary incontinence in Parkinson disease","volume":"76","author":"Vaughan","year":"2011","journal-title":"Neurology"},{"key":"B117","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1056\/NEJM199210223271701","article-title":"The effect of finasteride in men with benign prostatic hyperplasia. the finasteride study group","volume":"327","author":"Gormley","year":"1992","journal-title":"N Engl J Med"},{"key":"B118","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/S0090-4295(02)01905-2","article-title":"Efficacy and safety of a dual inhibitor of 5-alpha-reductase types 1 and 2 (dutasteride) in men with benign prostatic hyperplasia","volume":"60","author":"Roehrborn","year":"2002","journal-title":"Urology"},{"key":"B119","doi-asserted-by":"publisher","first-page":"514","DOI":"10.1016\/j.parkreldis.2015.02.025","article-title":"Randomized, controlled pilot trial of solifenacin succinate for overactive bladder in Parkinson's disease","volume":"21","author":"Zesiewicz","year":"2015","journal-title":"Parkinsonism Relat Disord"},{"key":"B120","doi-asserted-by":"publisher","first-page":"820816","DOI":"10.1155\/2011\/820816","article-title":"An overview of the clinical use of antimuscarinics in the treatment of overactive bladder","volume":"2011","author":"Athanasopoulos","year":"2011","journal-title":"Adv Urol"},{"key":"B121","doi-asserted-by":"publisher","first-page":"O53","DOI":"10.1111\/luts.12215","article-title":"Therapeutic efficacy of low-dose (25 mg) mirabegron therapy for patients with mild to moderate overactive bladder symptoms due to central nervous system diseases","volume":"11","author":"Chen","year":"2019","journal-title":"LUTS: Lower Urinary Tract Symptoms"},{"key":"B122","volume-title":"Urinary Incontinence in Neurological Disease: Management of Lower Urinary Tract Dysfunction in Neurological Disease","year":"2012"},{"key":"B123","volume-title":"Medicine AAoS International Classification of Sleep Disorders. 3rd Edn","year":"2014"},{"key":"B124","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1002\/ana.410250609","article-title":"Sleep abnormalities in progressive supranuclear palsy","volume":"25","author":"Aldrich","year":"1989","journal-title":"Ann Neurol"},{"key":"B125","doi-asserted-by":"publisher","first-page":"407","DOI":"10.1016\/j.sleep.2008.05.004","article-title":"Polysomnographic findings, video-based sleep analysis and sleep perception in progressive supranuclear palsy","volume":"10","author":"Sixel-Doring","year":"2009","journal-title":"Sleep Med"},{"key":"B126","first-page":"349","article-title":"REM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsy","volume":"28","author":"Arnulf","year":"2005","journal-title":"Sleep"},{"key":"B127","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.parkreldis.2011.10.018","article-title":"Comparison of REM sleep behaviour disorder variables between patients with progressive supranuclear palsy and those with Parkinson's disease","volume":"18","author":"Nomura","year":"2012","journal-title":"Parkinsonism Relat Disord"},{"key":"B128","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1136\/pgmj.72.847.293","article-title":"Nocturnal and respiratory disturbances in Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy)","volume":"72","author":"De Bruin","year":"1996","journal-title":"Postgrad Med J"},{"key":"B129","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/j.smrv.2008.06.001","article-title":"The treatments of chronic insomnia: a review of benzodiazepine receptor agonists and psychological and behavioral therapies","volume":"13","author":"Riemann","year":"2009","journal-title":"Sleep Med Rev"},{"key":"B130","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.jocn.2009.05.038","article-title":"The use of zolpidem in the treatment of progressive supranuclear palsy","volume":"17","author":"Cotter","year":"2010","journal-title":"J Clin Neurosci"},{"key":"B131","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1016\/j.jamda.2017.12.098","article-title":"Fall-risk-increasing drugs: A systematic review and meta-analysis: II. psychotropics","volume":"19","author":"Seppala","year":"2018","journal-title":"J Am Med Dir Assoc"},{"key":"B132","doi-asserted-by":"publisher","first-page":"865","DOI":"10.2165\/00003495-200059040-00014","article-title":"Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia","volume":"59","author":"Holm","year":"2000","journal-title":"Drugs"},{"key":"B133","doi-asserted-by":"publisher","first-page":"125","DOI":"10.5664\/jcsm.26304","article-title":"Hypnotics should not be considered for the initial treatment of chronic insomnia","volume":"1","author":"Stepanski","year":"2005","journal-title":"J Clin Sleep Med"},{"key":"B134","doi-asserted-by":"publisher","first-page":"343","DOI":"10.5665\/sleep.3410","article-title":"National use of prescription medications for insomnia: NHANES 1999-2010","volume":"37","author":"Bertisch","year":"2014","journal-title":"Sleep"},{"key":"B135","doi-asserted-by":"publisher","first-page":"307","DOI":"10.5664\/jcsm.6470","article-title":"Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine clinical practice guideline","volume":"13","author":"Sateia","year":"2017","journal-title":"J Clin Sleep Med"},{"key":"B136","doi-asserted-by":"publisher","first-page":"2340","DOI":"10.1016\/j.clinthera.2016.09.010","article-title":"Review of safety and efficacy of sleep medicines in older adults","volume":"38","author":"Schroeck","year":"2016","journal-title":"Clin Ther"},{"key":"B137","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.jsmc.2015.08.004","article-title":"Consequences of circadian disruption on neurologic health","volume":"10","author":"Videnovic","year":"2015","journal-title":"Sleep Med Clin"},{"key":"B138","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.smrv.2005.01.001","article-title":"Excessive daytime sleepiness in Parkinsonism","volume":"9","author":"Arnulf","year":"2005","journal-title":"Sleep Med Rev"},{"key":"B139","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.jsmc.2008.04.010","article-title":"Update on the diagnosis and management of sleep disturbances in dementia","volume":"3","author":"Boeve","year":"2008","journal-title":"Sleep Med Clin"},{"key":"B140","doi-asserted-by":"publisher","first-page":"zsx154","DOI":"10.1093\/sleep\/zsx154","article-title":"Sleepless night and day, the plight of progressive supranuclear palsy","volume":"40","author":"Walsh","year":"2017","journal-title":"Sleep"},{"key":"B141","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1016\/j.parkreldis.2010.01.002","article-title":"Sleep disturbances and brain MRI morphometry in Parkinson's disease, multiple system atrophy and progressive supranuclear palsy - a comparative study","volume":"16","author":"Gama","year":"2010","journal-title":"Parkinsonism Relat Disord"},{"key":"B142","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1056\/NEJMoa1308659","article-title":"Upper-airway stimulation for obstructive sleep apnea","volume":"370","author":"Strollo","year":"2014","journal-title":"N Engl J Med"},{"key":"B143","doi-asserted-by":"publisher","first-page":"2585","DOI":"10.1212\/WNL.0000000000003388","article-title":"Practice guideline summary: treatment of restless legs syndrome in adults: report of the guideline development, dissemination, and implementation subcommittee of the American Academy of Neurology","volume":"87","author":"Winkelman","year":"2016","journal-title":"Neurology"},{"key":"B144","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.sleep.2014.09.011","article-title":"Melatonin therapy for REM sleep behavior disorder: a critical review of evidence","volume":"16","author":"McGrane","year":"2015","journal-title":"Sleep Med"},{"key":"B145","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.sleep.2015.12.020","article-title":"A prospective, naturalistic follow-up study of treatment outcomes with clonazepam in rapid eye movement sleep behavior disorder","volume":"21","author":"Li","year":"2016","journal-title":"Sleep Med"},{"key":"B146","doi-asserted-by":"publisher","first-page":"1109","DOI":"10.1016\/j.parkreldis.2014.08.013","article-title":"Drooling in Parkinson's disease: a review","volume":"20","author":"Srivanitchapoom","year":"2014","journal-title":"Parkinsonism Relat Disord"},{"key":"B147","doi-asserted-by":"publisher","first-page":"S42","DOI":"10.1002\/mds.23884","article-title":"The movement disorder society evidence-based medicine review update: treatments for the non-motor symptoms of Parkinson's disease","volume":"26","author":"Seppi","year":"2011","journal-title":"Mov Disord"},{"key":"B148","unstructured":"2019"},{"key":"B149","unstructured":"2018"},{"key":"B150","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1111\/j.1468-1331.2010.03131.x","article-title":"Botulinum toxin assessment, intervention and aftercare for paediatric and adult drooling: international consensus statement","volume":"17","author":"Reddihough","year":"2010","journal-title":"Eur J Neurol"},{"key":"B151","doi-asserted-by":"publisher","first-page":"1010","DOI":"10.3390\/toxins5051010","article-title":"Sialorrhea: anatomy, pathophysiology and treatment with emphasis on the role of botulinum toxins","volume":"5","author":"Lakraj","year":"2013","journal-title":"Toxins"},{"key":"B152","doi-asserted-by":"publisher","first-page":"2430","DOI":"10.1002\/mds.21752","article-title":"Radiotherapy to the salivary glands as treatment of sialorrhea in patients with Parkinsonism","volume":"22","author":"Postma","year":"2007","journal-title":"Mov Disord"},{"key":"B153","doi-asserted-by":"publisher","first-page":"1318","DOI":"10.1002\/mds.10276","article-title":"Sublingual atropine for sialorrhea secondary to Parkinsonism: a pilot study","volume":"17","author":"Hyson","year":"2002","journal-title":"Mov Disord"},{"key":"B154","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1001\/archneur.58.2.259","article-title":"Progression of dysarthria and dysphagia in postmortem-confirmed Parkinsonian disorders","volume":"58","author":"Muller","year":"2001","journal-title":"Arch Neurol"},{"key":"B155","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1136\/jnnp.60.6.615","article-title":"Natural history of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) and clinical predictors of survival: a clinicopathological study","volume":"60","author":"Litvan","year":"1996","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B156","doi-asserted-by":"publisher","first-page":"1362","DOI":"10.1093\/brain\/awn065","article-title":"Clinical outcomes of progressive supranuclear palsy and multiple system atrophy","volume":"131","author":"O'Sullivan","year":"2008","journal-title":"Brain"},{"key":"B157","doi-asserted-by":"publisher","first-page":"e0135823","DOI":"10.1371\/journal.pone.0135823","article-title":"Impact of aspiration pneumonia on the clinical course of progressive supranuclear palsy: a retrospective cohort study","volume":"10","author":"Tomita","year":"2015","journal-title":"PLoS ONE"},{"key":"B158","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1002\/mds.23060","article-title":"Endoscopic characteristics and levodopa responsiveness of swallowing function in progressive supranuclear palsy","volume":"25","author":"Warnecke","year":"2010","journal-title":"Mov Disord"},{"key":"B159","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1007\/s00455-019-10073-2","article-title":"Dysphagia in progressive supranuclear palsy","volume":"35","author":"Clark","year":"2020","journal-title":"Dysphagia"},{"key":"B160","doi-asserted-by":"publisher","first-page":"1217","DOI":"10.1002\/lary.28885","article-title":"The role of vocal fold bowing on cough and swallowing dysfunction in progressive supranuclear palsy","volume":"131","author":"Enver","year":"2020","journal-title":"Laryngoscope"},{"key":"B161","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1016\/j.parkreldis.2015.09.043","article-title":"Swallowing disturbances in the corticobasal syndrome","volume":"21","author":"Grunho","year":"2015","journal-title":"Parkinsonism Relat Disord"},{"key":"B162","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1007\/s00455-013-9488-3","article-title":"Validation of the Yale Swallow Protocol: a prospective double-blinded videofluoroscopic study","volume":"29","author":"Suiter","year":"2014","journal-title":"Dysphagia"},{"key":"B163","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1002\/mds.21625","article-title":"Validation of a swallowing disturbance questionnaire for detecting dysphagia in patients with Parkinson's disease","volume":"22","author":"Manor","year":"2007","journal-title":"Mov Disord"},{"key":"B164","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1002\/mds.27964","article-title":"The progressive supranuclear palsy clinical deficits scale","volume":"35","author":"Piot","year":"2020","journal-title":"Mov Disord"},{"key":"B165","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1136\/jnnp-2018-318060","article-title":"Long-term effect of low frequency stimulation of STN on dysphagia, freezing of gait and other motor symptoms in PD","volume":"89","author":"Xie","year":"2018","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B166","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/PL00009600","article-title":"Effects of physostigmine on swallowing and oral motor functions in patients with progressive supranuclear palsy: a pilot study","volume":"14","author":"Frattali","year":"1999","journal-title":"Dysphagia"},{"key":"B167","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1016\/j.jns.2017.11.015","article-title":"Effect of Lee Silverman Voice Treatment (LSVT LOUD\u00ae) on swallowing and cough in Parkinson's disease: a pilot study","volume":"383","author":"Miles","year":"2017","journal-title":"J Neurol Sci"},{"key":"B168","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1136\/jnnp.72.1.31","article-title":"Swallowing and voice effects of Lee Silverman Voice Treatment (LSVT\u00ae): a pilot study","volume":"72","author":"El Sharkawi","year":"2002","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B169","doi-asserted-by":"publisher","first-page":"1654","DOI":"10.1212\/WNL.48.6.1654","article-title":"Characterizing swallowing abnormalities in progressive supranuclear palsy","volume":"48","author":"Litvan","year":"1997","journal-title":"Neurology"},{"key":"B170","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1001\/archneur.58.2.265","article-title":"Neuropathological correlates of dysarthria in progressive supranuclear palsy","volume":"58","author":"Kluin","year":"2001","journal-title":"Arch Neurol"},{"key":"B171","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1212\/01.wnl.0000223826.84080.97","article-title":"Measuring quality of life in PSP: the PSP-QoL","volume":"67","author":"Schrag","year":"2006","journal-title":"Neurology"},{"key":"B172","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1044\/jshd.4502.268","article-title":"DAF as instrumental treatment for dysarthria in progressive supranuclear palsy: a case report","volume":"45","author":"Hanson","year":"1980","journal-title":"J Speech Hear Disord"},{"key":"B173","first-page":"512","volume-title":"Motor Speech Disorders - E-book. 3rd Edn","author":"Duffy","year":"2013"},{"key":"B174","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1044\/jshr.1504.763","article-title":"Time-by-count measurement of diadochokinetic syllable rate","volume":"15","author":"Fletcher","year":"1972","journal-title":"J Speech Hear Res"},{"key":"B175","doi-asserted-by":"publisher","first-page":"165","DOI":"10.3109\/13682828009112541","article-title":"Frenchay dysarthria assessment","volume":"15","author":"Enderby","year":"1980","journal-title":"Br J Disord Commun"},{"key":"B176","first-page":"99","article-title":"Speech and voice deficits in Parkinsonian plus syndromes: can they be treated","volume":"6","author":"Countryman","year":"1994","journal-title":"NCVS Status Prog Rep"},{"key":"B177","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jcomdis.2015.06.002","article-title":"Communication impairments in people with progressive supranuclear palsy: a tutorial","volume":"56","author":"Kim","year":"2015","journal-title":"J Commun Disord"},{"key":"B178","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.jcomdis.2014.06.008","article-title":"The apraxia of speech rating scale: a tool for diagnosis and description of apraxia of speech","volume":"51","author":"Strand","year":"2014","journal-title":"J Commun Disord"},{"key":"B179","doi-asserted-by":"publisher","first-page":"1588","DOI":"10.1016\/j.brs.2019.07.017","article-title":"Cerebellar rTMS for motor control in progressive supranuclear palsy","volume":"12","author":"Dale","year":"2019","journal-title":"Brain Stimul"},{"key":"B180","doi-asserted-by":"publisher","first-page":"e0223621","DOI":"10.1371\/journal.pone.0223621","article-title":"Clinical use of SAND battery to evaluate language in patients with progressive supranuclear palsy","volume":"14","author":"Picillo","year":"2019","journal-title":"PLoS ONE"},{"key":"B181","doi-asserted-by":"publisher","first-page":"335","DOI":"10.3390\/brainsci11030335","article-title":"Effects of tDCS on sound duration in patients with apraxia of speech in primary progressive aphasia","volume":"11","author":"Themistocleous","year":"2021","journal-title":"Brain Sci."},{"key":"B182","doi-asserted-by":"publisher","first-page":"3","DOI":"10.14802\/jmd.15060","article-title":"Clinical approach to progressive supranuclear palsy","volume":"9","author":"Ling","year":"2016","journal-title":"J Mov Disord"},{"key":"B183","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1093\/arclin\/acs098","article-title":"Executive dysfunction is the primary cognitive impairment in progressive supranuclear palsy","volume":"28","author":"Gerstenecker","year":"2013","journal-title":"Arch Clin Neuropsychol"},{"key":"B184","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1212\/WNL.45.8.1477","article-title":"The neuropsychological pattern of corticobasal degeneration: comparison with progressive supranuclear palsy and Alzheimer's disease","volume":"45","author":"Pillon","year":"1995","journal-title":"Neurology"},{"key":"B185","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1016\/S1474-4422(17)30157-6","article-title":"Advances in progressive supranuclear palsy: new diagnostic criteria, biomarkers, and therapeutic approaches","volume":"16","author":"Boxer","year":"2017","journal-title":"Lancet Neurol"},{"key":"B186","unstructured":"Cognitive Screening Tests for Dementia2018"},{"key":"B187","doi-asserted-by":"publisher","first-page":"1621","DOI":"10.1212\/WNL.55.11.1621","article-title":"The FAB: a frontal assessment battery at bedside","volume":"55","author":"Dubois","year":"2000","journal-title":"Neurology"},{"key":"B188","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1136\/jnnp-2012-303618","article-title":"The Addenbrooke's Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with Parkinsonian disorders","volume":"84","author":"Rittman","year":"2013","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B189","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1093\/brain\/awh391","article-title":"Cholinergic systems in progressive supranuclear palsy","volume":"128","author":"Warren","year":"2005","journal-title":"Brain"},{"key":"B190","doi-asserted-by":"publisher","first-page":"499","DOI":"10.2217\/nmt-2016-0027","article-title":"Managing cognition in progressive supranuclear palsy","volume":"6","author":"Rittman","year":"2016","journal-title":"Neurodegener Dis Manag"},{"key":"B191","first-page":"206","article-title":"The test of copying a complex figure: a contribution to the study of perception and memory","volume":"30","author":"Osterrieth","year":"1944","journal-title":"Arch. Psychol."},{"key":"B192","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S1474-4422(12)70320-4","article-title":"Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial","volume":"12","author":"Boxer","year":"2013","journal-title":"Lancet Neurol"},{"key":"B193","doi-asserted-by":"publisher","first-page":"749","DOI":"10.3233\/JAD-2010-101632","article-title":"Memantine in behavioral variant frontotemporal dementia: negative results","volume":"23","author":"Vercelletto","year":"2011","journal-title":"J Alzheimer's Dis"},{"key":"B194","doi-asserted-by":"publisher","first-page":"308","DOI":"10.1097\/WAD.0b013e3181cf468d","article-title":"Pilot trial of memantine in primary progressive aphasia","volume":"24","author":"Johnson","year":"2010","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"B195","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1097\/JGP.0b013e31823033f3","article-title":"Serotonergic function and treatment of behavioral and psychological symptoms of frontotemporal dementia","volume":"20","author":"Herrmann","year":"2012","journal-title":"Am J Geriatr Psychiatry"},{"key":"B196","doi-asserted-by":"publisher","first-page":"646","DOI":"10.1212\/01.CON.0000466658.05156.54","article-title":"Executive dysfunction","volume":"21","author":"Rabinovici","year":"2015","journal-title":"Continuum."},{"key":"B197","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1002\/gps.4245","article-title":"Target risk factors for dementia prevention: a systematic review and delphi consensus study on the evidence from observational studies","volume":"30","author":"Deckers","year":"2015","journal-title":"Int J Geriatr Psychiatry"},{"key":"B198","doi-asserted-by":"publisher","first-page":"e537","DOI":"10.1212\/WNL.0000000000007893","article-title":"Language boosting by transcranial stimulation in progressive supranuclear palsy","volume":"93","author":"Valero-Cabr\u00e9","year":"2019","journal-title":"Neurology"},{"key":"B199","doi-asserted-by":"publisher","first-page":"860","DOI":"10.1093\/brain\/123.5.860","article-title":"Limb apraxias: higher-order disorders of sensorimotor integration","volume":"123","author":"Leiguarda","year":"2000","journal-title":"Brain"},{"key":"B200","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1212\/WNL.0b013e31827f0fd1","article-title":"Criteria for the diagnosis of corticobasal degeneration","volume":"80","author":"Armstrong","year":"2013","journal-title":"Neurology"},{"key":"B201","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1212\/WNL.56.7.957","article-title":"Comparison of apraxia in corticobasal degeneration and progressive supranuclear palsy","volume":"56","author":"Pharr","year":"2001","journal-title":"Neurology"},{"key":"B202","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1080\/13803395.2014.951315","article-title":"Short apraxia screening test","volume":"36","author":"Leiguarda","year":"2014","journal-title":"J Clin Exp Neuropsychol"},{"key":"B203","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1136\/jnnp.2010.213371","article-title":"A new bedside test of gestures in stroke: the apraxia screen of TULIA (AST)","volume":"82","author":"Vanbellingen","year":"2011","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"B204","volume-title":"TOLA: Test of Oral and Limb Apraxia","author":"Helm-Estabrooks","year":"1992"},{"key":"B205","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1001\/archneur.1980.00500500036003","article-title":"Imitating gestures: a quantitative approach to ideomotor apraxia","volume":"37","author":"De Renzi","year":"1980","journal-title":"Arch Neurol"},{"key":"B206","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1111\/j.1468-1331.2009.02741.x","article-title":"Comprehensive assessment of gesture production: a new test of upper limb apraxia (TULIA)","volume":"17","author":"Vanbellingen","year":"2010","journal-title":"Eur J Neurol"},{"key":"B207","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/13803390902791646","article-title":"Florida Apraxia Battery Extended and Revised Sydney (FABERS): design, description, and a healthy control sample","volume":"32","author":"Power","year":"2010","journal-title":"J Clin Exp Neuropsychol"},{"key":"B208","doi-asserted-by":"publisher","first-page":"1269","DOI":"10.1007\/s00415-011-6336-y","article-title":"Diagnosis and treatment of upper limb apraxia","volume":"259","author":"Dovern","year":"2012","journal-title":"J Neurol"},{"key":"B209","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/j.apmr.2007.08.162","article-title":"Mirror therapy improves hand function in subacute stroke: a randomized controlled trial","volume":"89","author":"Yavuzer","year":"2008","journal-title":"Arch Phys Med Rehabil"},{"key":"B210","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1097\/MRR.0b013e32831e4546","article-title":"Improvements in limb kinetic apraxia by repetition of a newly designed facilitation exercise in a patient with corticobasal degeneration","volume":"32","author":"Kawahira","year":"2009","journal-title":"Int J Rehabil Res"},{"key":"B211","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.1111\/ene.12748","article-title":"Left parietal cortex transcranial direct current stimulation enhances gesture processing in corticobasal syndrome","volume":"22","author":"Bianchi","year":"2015","journal-title":"Eur J Neurol"},{"key":"B212","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1089\/tmj.2017.0295","article-title":"Telemedicine use for movement disorders: a global survey","volume":"24","author":"Hassan","year":"2018","journal-title":"Telemed J E Health."},{"key":"B213","doi-asserted-by":"publisher","first-page":"541","DOI":"10.1016\/S1474-4422(17)30167-9","article-title":"The promise of telemedicine for chronic neurological disorders: the example of Parkinson's disease","volume":"16","author":"Schneider","year":"2017","journal-title":"Lancet Neurol"},{"key":"B214","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1002\/mds.22498","article-title":"Telemedicine for the care of nursing home residents with Parkinson's disease","volume":"24","author":"Biglan","year":"2009","journal-title":"Mov Disord"},{"key":"B215","doi-asserted-by":"publisher","first-page":"1652","DOI":"10.1002\/mds.23145","article-title":"Increasing access to specialty care: a pilot, randomized controlled trial of telemedicine for Parkinson's disease","volume":"25","author":"Dorsey","year":"2010","journal-title":"Mov Disord"},{"key":"B216","doi-asserted-by":"publisher","first-page":"g1838","DOI":"10.1136\/bmj.g1838","article-title":"Revolutionising management of chronic disease: the ParkinsonNet approach","volume":"348","author":"Bloem","year":"2014","journal-title":"BMJ"},{"key":"B217","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1097\/JNN.0000000000000194","article-title":"The CurePSP Care Guide: a telephonic nursing intervention for individuals and families living with progressive supranuclear palsy","volume":"48","author":"Dunlop","year":"2016","journal-title":"J Neurosci Nurs"},{"key":"B218","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1002\/mdc3.12037","article-title":"Challenges faced by patients with progressive supranuclear palsy and their families","volume":"1","author":"Moore","year":"2014","journal-title":"Mov Disord Clin Pract."},{"key":"B219","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1002\/mdc3.12243","article-title":"Clinimetric analysis of the motor section of the progressive supranuclear palsy rating scale: reliability and factor analysis","volume":"3","author":"Hall","year":"2016","journal-title":"Mov Disord Clin Pract."},{"key":"B220","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1001\/jamaneurol.2019.4992","article-title":"Comparison of integrated outpatient palliative care with standard care in patients with Parkinson disease and related disorders: a randomized clinical trial","volume":"77","author":"Kluger","year":"2020","journal-title":"JAMA Neurol"},{"key":"B221","doi-asserted-by":"publisher","first-page":"364","DOI":"10.3389\/fneur.2017.00364","article-title":"The Parkinson care advocate: integrating care delivery","volume":"8","author":"Sokol","year":"2017","journal-title":"Front Neurol"},{"key":"B222","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41531-019-0098-0","article-title":"Advance care planning in Parkinson's disease: ethical challenges and future directions","volume":"5","author":"Sokol","year":"2019","journal-title":"NPJ Parkinsons Dis"},{"key":"B223","doi-asserted-by":"publisher","first-page":"1155","DOI":"10.1089\/jpm.2020.0129","article-title":"Meaning and dignity therapies for psychoneurology in neuropalliative care: a vision for the future","volume":"23","author":"Sokol","year":"2020","journal-title":"J Palliat Med."},{"key":"B224","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.parkreldis.2019.01.026","article-title":"End of life planning in Parkinsonian diseases","volume":"62","author":"Gillard","year":"2019","journal-title":"Parkinsonism Relat Disord"},{"key":"B225","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1177\/1049909114565110","article-title":"Managing advanced progressive supranuclear palsy and corticobasal degeneration in a palliative care unit: admission triggers and outcomes","volume":"33","author":"B\u00fckki","year":"2016","journal-title":"Am J Hosp Palliat Care."},{"key":"B226","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1097\/01376517-200608000-00007","article-title":"Characteristics and symptom management of progressive supranuclear palsy: a multidisciplinary approach","volume":"38","author":"Ward","year":"2006","journal-title":"J Neurosci Nurs"},{"key":"B227","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1377\/hlthaff.2019.00004","article-title":"Beyond functional support: the range of health-related tasks performed in the home by paid caregivers in New York","volume":"38","author":"Reckrey","year":"2019","journal-title":"Health Aff"},{"key":"B228","doi-asserted-by":"publisher","first-page":"CD007760","DOI":"10.1002\/14651858.CD007760.pub2","article-title":"Effectiveness and cost-effectiveness of home palliative care services for adults with advanced illness and their caregivers","volume":"6","author":"Gomes","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"B229","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1111\/j.1532-5415.2010.02859.x","article-title":"Hospitalizations and skilled nursing facility admissions before and after the implementation of a home-based primary care program","volume":"58","author":"Wajnberg","year":"2010","journal-title":"J Am Geriatr Soc"},{"key":"B230","doi-asserted-by":"publisher","first-page":"1226","DOI":"10.1111\/jgs.15337","article-title":"Interdisciplinary home visits for individuals with advanced Parkinson's disease and related disorders","volume":"66","author":"Fleisher","year":"2018","journal-title":"J Am Geriatr Soc"},{"key":"B231","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1001\/jama.2012.207624","article-title":"Change in end-of-life care for Medicare beneficiaries: site of death, place of care, and health care transitions in 2000, 2005, and 2009","volume":"309","author":"Teno","year":"2013","journal-title":"JAMA"},{"key":"B232","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1212\/WNL.0000000000001715","article-title":"Nursing home and end-of-life care in Parkinson disease","volume":"85","author":"Safarpour","year":"2015","journal-title":"Neurology"},{"key":"B233","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1007\/s00415-019-09632-2","article-title":"Suicidal risk and demoralization in Parkinson disease","volume":"267","author":"Elfil","year":"2020","journal-title":"J Neurol"},{"key":"B234","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1017\/S1478951512000752","article-title":"The physician's role in physician-assisted suicide","volume":"10","author":"Breitbart","year":"2012","journal-title":"Palliat Support Care."},{"key":"B235","first-page":"218","volume-title":"The Hidden Victims of Alzheimer's Disease: Families Under Stress","author":"Zarit","year":"1985"},{"key":"B236","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s11136-015-1071-y","article-title":"Development and validation of a carers quality-of-life questionnaire for Parkinsonism (PQoL carers)","volume":"25","author":"Pillas","year":"2016","journal-title":"Qual Life Res."},{"key":"B237","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1093\/brain\/awn291","article-title":"Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study","volume":"132","author":"Bensimon","year":"2009","journal-title":"Brain"},{"key":"B238","doi-asserted-by":"publisher","first-page":"676","DOI":"10.1016\/S1474-4422(14)70088-2","article-title":"Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2\/3 trial","volume":"13","author":"Boxer","year":"2014","journal-title":"Lancet Neurol"},{"key":"B239","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1002\/mds.25824","article-title":"A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy","volume":"29","author":"Tolosa","year":"2014","journal-title":"Mov Disord"},{"key":"B240","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/S1474-4422(19)30139-5","article-title":"Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial","volume":"18","author":"Boxer","year":"2019","journal-title":"Lancet Neurol"},{"key":"B241","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1097\/WCO.0000000000000836","article-title":"Immunotherapy in progressive supranuclear palsy","volume":"33","author":"Vaswani","year":"2020","journal-title":"Curr Opin Neurol"},{"key":"B242","doi-asserted-by":"publisher","first-page":"134919","DOI":"10.1016\/j.neulet.2020.134919","article-title":"Targeting tau: clinical trials and novel therapeutic approaches","volume":"731","author":"VandeVrede","year":"2020","journal-title":"Neurosci Lett"},{"key":"B243","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1002\/mds.25815","article-title":"Tideglusib reduces progression of brain atrophy in progressive supranuclear palsy in a randomized trial","volume":"29","author":"H\u00f6glinger","year":"2014","journal-title":"Mov Disord"},{"key":"B244","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1176\/jnp.23.3.jnp242","article-title":"Psychopharmacological neuroprotection in neurodegenerative diseases, part III: criteria-based assessment: a report of the ANPA committee on research","volume":"23","author":"Lauterbach","year":"2011","journal-title":"J Neuropsychiatry Clin Neurosci"},{"key":"B245","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1001\/jamaneurol.2019.3812","article-title":"Reactions to multiple ascending doses of the microtubule stabilizer TPI-287 in patients with Alzheimer disease, progressive supranuclear palsy, and corticobasal syndrome: a randomized clinical trial","volume":"77","author":"Tsai","year":"2020","journal-title":"JAMA Neurol"},{"key":"B246","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1002\/mdc3.12940","article-title":"Open-label phase 1 futility studies of salsalate and young plasma in progressive supranuclear palsy","volume":"7","author":"VandeVrede","year":"2020","journal-title":"Mov Disord Clin Pract"},{"key":"B247","doi-asserted-by":"publisher","first-page":"148","DOI":"10.11124\/JBISRIR-2016-2002352","article-title":"Effectiveness of allied health therapy in the symptomatic management of progressive supranuclear palsy: a systematic review","volume":"14","author":"Tilley","year":"2016","journal-title":"JBI Database Syst Rev Implement Rep"},{"key":"B248","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1186\/s12883-019-1539-4","article-title":"Exercise and progressive supranuclear palsy: the need for explicit exercise reporting","volume":"19","author":"Slade","year":"2019","journal-title":"BMC Neurol"},{"key":"B249","first-page":"569","article-title":"The Lee Silverman Voice Treatment (LSVT\u00ae) speech therapy in progressive supranuclear palsy","volume":"51","author":"Sale","year":"2015","journal-title":"Eur J Phys Rehabil Med"},{"key":"B250","doi-asserted-by":"publisher","first-page":"e0170927","DOI":"10.1371\/journal.pone.0170927","article-title":"Rehabilitation in progressive supranuclear palsy: effectiveness of two multidisciplinary treatments","volume":"12","author":"Clerici","year":"2017","journal-title":"PLoS ONE"},{"key":"B251","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.parkreldis.2020.04.014","article-title":"Progressive supranuclear palsy: advances in diagnosis and management","volume":"73","author":"Coughlin","year":"2020","journal-title":"Parkinsonism Relat Disord"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2021.694872\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,2]],"date-time":"2021-07-02T14:59:17Z","timestamp":1625237957000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2021.694872\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,1]]},"references-count":251,"alternative-id":["10.3389\/fneur.2021.694872"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2021.694872","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,1]]},"article-number":"694872"}}