{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:16:18Z","timestamp":1792466178705,"version":"4.5.0"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T00:00:00Z","timestamp":1638403200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p><jats:bold>Objective:<\/jats:bold> This study aimed to investigate the clinical efficacy of robot-assisted neuroendoscopic hematoma evacuation combined intracranial pressure (ICP) monitoring for the treatment of hypertensive intracerebral hemorrhage (HICH).<\/jats:p><jats:p><jats:bold>Patients and Methods:<\/jats:bold> A retrospective analysis of 53 patients with HICH undergoing neuroendoscopic hematoma evacuation in our department from January 2016 to December 2020 was performed. We divided the patients into two groups: the neuroendoscopic group (<jats:italic>n<\/jats:italic> = 32) and the robot-assisted neuroendoscopic combined ICP monitoring group (<jats:italic>n<\/jats:italic> = 21). Data on clinical characteristics, treatment effects, and outcomes were retrospectively reviewed and analyzed between these two groups.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> The operation time of the procedure of the neuroendoscopic group was significantly longer than that of the robot-assisted neuroendoscopic combined ICP-monitoring group (mean time 153.8 \u00b1 16.8 vs. 132.8 \u00b1 15.7 min, <jats:italic>P<\/jats:italic> &amp;lt; 0.001). The intraoperative blood loss was significantly less in the robot-assisted neuroendoscopic combined ICP-monitoring group than in the neuroendoscopic group (215.4 \u00b1 28.3 vs. 190.1 \u00b1 25.6 ml, <jats:italic>P<\/jats:italic> = 0.001). However, the patients undergoing neuroendoscopic had a comparable hematoma clearance rate with those undergoing robot-assisted neuroendoscopic combined ICP monitoring (85.2 \u00b1 4.8 vs. 89.2 \u00b1 5.4%, <jats:italic>P<\/jats:italic> = 0.997). The complications rate was greater in the endoscopic group (25%) than in the robot-assisted neuroendoscopic combined ICP-monitoring group (9.5%) but without significant difference (<jats:italic>P<\/jats:italic> = 0.159). We also found that the dose of used mannitol was significantly less in the ICP monitoring group (615.2 \u00b1 63.8 vs. 547.8 \u00b1 65.3 ml, <jats:italic>P<\/jats:italic> &amp;lt; 0.001) and there was a significant difference in modified Rankin scale (mRS) score at discharge, patients with less mRS score in the robot-assisted neuroendoscopic combined ICP monitoring group than in the neuroendoscopic group (3.0 \u00b1 1.0 vs. 3.8 \u00b1 0.8, <jats:italic>p<\/jats:italic> = 0.011). Patients undergoing robot-assisted neuroendoscopic combined ICP monitoring had better 6-month functional outcomes, and there was a significant difference between the two groups (<jats:italic>p<\/jats:italic> = 0.004). Besides, multivariable analysis shows younger age, no complication, and robot-assisted neuroendoscopic combined ICP monitoring were predictors of 6-month favorable outcomes for the patients with HICH.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> Robot-assisted neuroendoscopic hematoma evacuation combined with ICP monitoring appears to be safer and more effective as compared to the neuroendoscopic hematoma evacuation in the treatment of HICH. Robot-assisted neuroendoscopic hematoma evacuation combined with ICP monitoring might improve the clinical effect and treatment outcomes of the patients with HICH.<\/jats:p>","DOI":"10.3389\/fneur.2021.722924","type":"journal-article","created":{"date-parts":[[2021,12,2]],"date-time":"2021-12-02T07:03:10Z","timestamp":1638428590000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":22,"title":["Effect of Robot-Assisted Neuroendoscopic Hematoma Evacuation Combined Intracranial Pressure Monitoring for the Treatment of Hypertensive Intracerebral 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