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Neurol."],"abstract":"<jats:p>Craniopharyngioma is a congenital brain tumor with clinical characteristics of hypothalamic-pituitary dysfunction, increased intracranial pressure, and visual field disorder, among other injuries. Its clinical diagnosis mainly depends on radiological examinations (such as Computed Tomography, Magnetic Resonance Imaging). However, assessing numerous radiological images manually is a challenging task, and the experience of doctors has a great influence on the diagnosis result. The development of artificial intelligence has brought about a great transformation in the clinical diagnosis of craniopharyngioma. This study reviewed the application of artificial intelligence technology in the clinical diagnosis of craniopharyngioma from the aspects of differential classification, prediction of tissue invasion and gene mutation, prognosis prediction, and so on. Based on the reviews, the technical route of intelligent diagnosis based on the traditional machine learning model and deep learning model were further proposed. Additionally, in terms of the limitations and possibilities of the development of artificial intelligence in craniopharyngioma diagnosis, this study discussed the attentions required in future research, including few-shot learning, imbalanced data set, semi-supervised models, and multi-omics fusion.<\/jats:p>","DOI":"10.3389\/fneur.2021.752119","type":"journal-article","created":{"date-parts":[[2022,1,6]],"date-time":"2022-01-06T05:39:57Z","timestamp":1641447597000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":14,"title":["Application of Artificial Intelligence in Diagnosis of Craniopharyngioma"],"prefix":"10.3389","volume":"12","author":[{"given":"Caijie","family":"Qin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxing","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinsheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xibo","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,1,6]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1210\/er.2013-1115","article-title":"Craniopharyngioma","volume":"35","author":"M\u00fcller","year":"2014","journal-title":"Endocrine Rev"},{"key":"B2","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1007\/s11102-012-0428-2","article-title":"Mortality and morbidity in adult craniopharyngioma","volume":"16","author":"Erfurth","year":"2013","journal-title":"Pituitary"},{"key":"B3","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1002\/pd.1970101002","article-title":"Prenatal diagnosis of a craniopharyngioma using ultrasonography and magnetic resonance imaging","volume":"10","author":"Bailey","year":"1990","journal-title":"Prenat Diagn"},{"key":"B4","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1159\/000055967","article-title":"Radical surgery in a neonate with craniopharyngioma","volume":"33","author":"M\u00fcller-Scholden","year":"2000","journal-title":"Pediatr Neurosurg"},{"key":"B5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40478-016-0287-6","article-title":"Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles","volume":"4","author":"H\u00f6lsken","year":"2016","journal-title":"Acta Neuropathol Commun"},{"key":"B6","doi-asserted-by":"publisher","first-page":"403","DOI":"10.3171\/2010.8.PEDS09385","article-title":"Surgical management of giant pediatric craniopharyngiomas","volume":"6","author":"Elliott","year":"2010","journal-title":"J Neurosurg Pediatr"},{"key":"B7","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3389\/fgene.2018.00049","article-title":"Rathke's cleft cyst as origin of a pediatric papillary craniopharyngioma","volume":"9","author":"Schlaffer","year":"2018","journal-title":"Front Genet"},{"key":"B8","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1007\/s11102-012-0414-8","article-title":"Surgery for craniopharyngioma","volume":"119","author":"Ashkenazi","year":"2013","journal-title":"Harefuah"},{"key":"B9","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1016\/j.wneu.2021.01.044","article-title":"Predictors of postoperative visual outcome following surgical intervention for craniopharyngiomas","volume":"148","author":"Kopparapu","year":"2021","journal-title":"World Neurosurg"},{"key":"B10","doi-asserted-by":"publisher","first-page":"3298","DOI":"10.1210\/jc.2003-031751","article-title":"Longitudinal study on growth and body mass index before and after diagnosis of childhood craniopharyngioma","volume":"89","author":"M\u00fcller","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"B11","doi-asserted-by":"publisher","first-page":"388","DOI":"10.2478\/raon-2019-0036","article-title":"Advances in the management of craniopharyngioma in children and adults","volume":"59","author":"Jensterle","year":"2019","journal-title":"Radiol Oncol"},{"key":"B12","doi-asserted-by":"publisher","first-page":"949","DOI":"10.3171\/2018.5.JNS18153","article-title":"Harvey Cushing's craniopharyngioma treatment: Part 1. 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