{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:14:14Z","timestamp":1785248054931,"version":"3.55.0"},"reference-count":34,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T00:00:00Z","timestamp":1643932800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The clinical efficacy of triple semicircular canal occlusion (TSCO) and vestibular nerve resection (VNS) for patients with M\u00e9ni\u00e8re's disease has been unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore changes in vestibular symptoms after TSCO and its advantages compared to the classical operation of VNS in patients with Meni\u00e8re's disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In total, 36 patients with Meni\u00e8re's disease performed TSCO or VNS at Shanghai Jiao Tong University Affiliated Sixth People's Hospital, China from May 2005 to July 2021, and all of them were enrolled in our study. Twelve of them underwent TSCO, 23 underwent VNS, and 1 had both treatments. We compared the demographic parameters, clinical symptoms, and selected test results between the two surgical methods. Ten patients each who underwent TSCO and VNS completed the follow-up. We collected and compared data pertaining to changes in vestibular symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant difference in demographic parameters, clinical symptoms, or auditory or vestibular test results was detected between the two groups preoperatively. The TSCO group with vertigo as the main complaint experienced less residual paroxysmal dizziness after surgery than the VNS group (<jats:italic>P<\/jats:italic> = 0.020). Also, 57% of the patients in the VNS group had unsteadiness after surgery, while no such problems were reported in the TSCO group (<jats:italic>P<\/jats:italic> = 0.025).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study shows that TSCO controls vertigo in most Meni\u00e8re's disease patients, and also has the advantage of lower rates of postoperative paroxysmal dizziness and unsteadiness than VNS. Thus, TSCO may be an effective surgery for refractory Meni\u00e8re's disease.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2022.797699","type":"journal-article","created":{"date-parts":[[2022,2,4]],"date-time":"2022-02-04T05:38:45Z","timestamp":1643953125000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Changes of Vestibular Symptoms in Meni\u00e8re's Disease After Triple Semicircular Canal Occlusion: A Long-Term Follow-Up Study"],"prefix":"10.3389","volume":"13","author":[{"given":"Yumeng","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maoxiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingxiu","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuangzhuang","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqin","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengnong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongzhen","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shankai","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,2,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3233\/VES-150549","article-title":"Diagnostic criteria for Meniere's disease","volume":"25","author":"Lopez-Escamez","year":"2015","journal-title":"J Vestib Res."},{"key":"B2","doi-asserted-by":"publisher","first-page":"206","DOI":"10.3109\/00016489509121906","article-title":"Epidemiological and clinical characteristics of Meniere's disease in Japan","volume":"519","author":"Watanabe","year":"1995","journal-title":"Acta Otolaryngol Suppl."},{"key":"B3","doi-asserted-by":"publisher","first-page":"S1","DOI":"10.1177\/0194599820909438","article-title":"Clinical practice guideline: Meniere's disease","volume":"162","author":"Basura","year":"2020","journal-title":"Otolaryngol Head Neck Surg."},{"key":"B4","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1177\/0194599818803612","article-title":"Quality-of-life outcomes following surgical treatment of Meniere's disease: a systematic review and meta-analysis","volume":"160","author":"Ballard","year":"2019","journal-title":"Otolaryngol Head Neck Surg."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1007\/s00405-016-4294-9","article-title":"Is gentamycin delivery via sustained-release vehicles a safe and effective treatment for refractory Meniere's disease? 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