{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:06:44Z","timestamp":1753891604765,"version":"3.41.2"},"reference-count":8,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T00:00:00Z","timestamp":1649030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>Familial lateral temporal lobe epilepsy (FLTLE) is genetic focal epilepsy usually characterised by auditory symptoms. Most FLTLE cases can be controlled by anti-seizure medications, and to our best knowledge, there are no previous reports about stereoelectroencephalography (SEEG) used for patients with FLTLE. In this report, we present two patients with FLTLE in one family and their SEEG performances, together with <jats:sup>18<\/jats:sup>F-fluorodeoxyglucose (<jats:sup>18<\/jats:sup>F-FDG) PET and MRI results. In case 1, fast activities originated from the right superior temporal gyrus and spread rapidly to the right anterior insular lobe and hippocampus. In case 2, there were two seizure patterns: (1) The fast activities or sharp slow waves were identified at the left superior temporal gyrus, then, sharp waves and spike waves spread in the left superior temporal gyrus; (2) There were fast activities and slow-wave oscillation originated in the left superior temporal gyrus, then, the fast activities spread in the left superior temporal gyrus and finally spread to the other sites. An SEEG-guided radiofrequency thermocoagulation was performed for both patients and one of them underwent resection surgery. Seizures are well-controlled and the patients are very satisfied with the therapeutic effects.<\/jats:p>","DOI":"10.3389\/fneur.2022.864070","type":"journal-article","created":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T06:30:16Z","timestamp":1649053816000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Case Report: Stereoelectroencephalography and Stereoelectroencephalography-Guided Radiofrequency Thermocoagulation in Familial Lateral Temporal Lobe Epilepsy"],"prefix":"10.3389","volume":"13","author":[{"given":"Ziqi","family":"Wei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolai","family":"Ye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changquan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiwen","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puming","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiangqiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2022,4,4]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1111\/j.1528-1167.2005.00361.x","article-title":"Genetic focal epilepsies: state of the art and paths to the future","volume":"46","author":"Andermann","year":"2005","journal-title":"Epilepsia."},{"key":"B2","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1111\/epi.13298","article-title":"Is SEEG safe? A systematic review and meta-analysis of stereo-electroencephalography\u2013related complications","volume":"57","author":"Mullin J","year":"2016","journal-title":"Epilepsia."},{"key":"B3","doi-asserted-by":"publisher","first-page":"106475","DOI":"10.1016\/j.eplepsyres.2020.106475","article-title":"Localization of the epileptogenic zone based on ictal stereo-electroencephalogram: brain network and single-channel signal feature analysis","volume":"167","author":"An","year":"2020","journal-title":"Epilepsy Res."},{"key":"B4","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1111\/cbdd.13858","article-title":"Temporal lobe epilepsy: what do we understand about protein alterations?","volume":"98","author":"Perveen","year":"2021","journal-title":"Chem Biol Drug Des."},{"key":"B5","doi-asserted-by":"publisher","first-page":"2441","DOI":"10.1093\/brain\/aww187","article-title":"Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections","volume":"139","author":"Tai X","year":"2016","journal-title":"Brain."},{"key":"B6","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1212\/WNL.50.2.554","article-title":"Familial temporal lobe epilepsy: a clinically heterogeneous syndrome","volume":"50","author":"Cendes","year":"1998","journal-title":"Neurology"},{"key":"B7","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.seizure.2015.07.014","article-title":"Familial temporal lobe epilepsy due to focal cortical dysplasia type IIIa","volume":"31","author":"Fabera","year":"2015","journal-title":"Seizure."},{"key":"B8","doi-asserted-by":"publisher","first-page":"604","DOI":"10.2176\/nmc.51.604","article-title":"Familial lateral temporal lobe epilepsy confirmed with intracranial electroencephalography and successfully treated by surgery","volume":"51","author":"Koizumi","year":"2011","journal-title":"Neurologia Medico-Chirurgica"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2022.864070\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T06:30:20Z","timestamp":1649053820000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2022.864070\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,4]]},"references-count":8,"alternative-id":["10.3389\/fneur.2022.864070"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2022.864070","relation":{},"ISSN":["1664-2295"],"issn-type":[{"type":"electronic","value":"1664-2295"}],"subject":[],"published":{"date-parts":[[2022,4,4]]},"article-number":"864070"}}