{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:16:05Z","timestamp":1790705765362,"version":"4.1.0"},"reference-count":60,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T00:00:00Z","timestamp":1658188800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Time perception comprises the subjective experience of passing of time and of the duration of an event. Although already described in some neurological and psychiatric conditions, there is a paucity of details regarding this neurocognitive change in stroke patients. We aimed to describe time perception dysfunction in stroke patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a systematic review of the literature in Pubmed, PsycInfo and EMBASE including manuscripts from their inception until December 2020. We collected data regarding the type of time perception that was detected, type of stroke, most common location of lesions, evaluation tests that were used and time of evaluation after stroke onset.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 27 manuscripts were selected, concerning a total of 418 patients (<jats:italic>n<\/jats:italic>= 253 male; 60.5%). Most manuscripts (<jats:italic>n<\/jats:italic>= 21) evaluated patients with ischaemic lesions (<jats:italic>n<\/jats:italic>= 407; 97.4%). The majority referred to evaluations between 2 months and seven years after stroke. Underestimation in temporal evaluation in sub- and supra-second was the most common dysfunction (<jats:italic>n<\/jats:italic>= 165; 41.7%). Overestimation of time (<jats:italic>n<\/jats:italic>= 116; 27.8%) and impaired time interval comparison (<jats:italic>n<\/jats:italic>= 88; 22.2%) were also found. Most patients had right hemisphere lesions (<jats:italic>n<\/jats:italic>= 219 patients; 52.4%). Common reported lesion locations included the thalamus, insula, basal ganglia, dorsolateral prefrontal cortex, parietal cortex including supramarginal, angular gyrus and right inferior parietal cortex and cerebellum.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There are multiple stroke locations associated with time perception dysfunction, which highlights the complex system involved in time perception. There is still scarce knowledge about specific time perception deficits after stroke. Most studies rely in psychometric analysis without clear clinical and functional translation, namely regarding impact on daily activities.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2022.938367","type":"journal-article","created":{"date-parts":[[2022,7,19]],"date-time":"2022-07-19T06:19:28Z","timestamp":1658211568000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Time perception changes in stroke patients: A systematic literature review"],"prefix":"10.3389","volume":"13","author":[{"given":"Pedro","family":"Coelho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana Amado","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Nascimento Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Catarina","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2022,7,19]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"5939","DOI":"10.4081\/ni.2016.5939","article-title":"Time perception mechanisms at central nervous system","volume":"8","author":"Fontes","year":"2016","journal-title":"Neurol Int."},{"key":"B2","doi-asserted-by":"publisher","first-page":"567","DOI":"10.2174\/18715273113129990080","article-title":"Time perception distortion in neuropsychiatric and neurological disorders","volume":"12","author":"Teixeira","year":"2013","journal-title":"CNS Neurol Disord Drug Targets."},{"key":"B3","doi-asserted-by":"crossref","first-page":"329","DOI":"10.55782\/ane-2004-1517","article-title":"The neural correlates of cognitive time management: a review","volume":"64","author":"Rubia","year":"2004","journal-title":"Acta Neurobiol Exp."},{"key":"B4","doi-asserted-by":"publisher","first-page":"112232","DOI":"10.1016\/j.bbr.2019.112232","article-title":"Understanding time perception through non-invasive brain stimulation techniques: A review of studies","volume":"377","author":"Mioni","year":"2020","journal-title":"Behav Brain Res."},{"key":"B5","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1016\/j.neuroimage.2009.09.064","article-title":"The image of time: a voxel-wise meta-analysis","volume":"49","author":"Wiener","year":"2010","journal-title":"NeuroImage."},{"key":"B6","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.tics.2008.04.002","article-title":"Dedicated and intrinsic models of time perception","volume":"12","author":"Ivry","year":"2008","journal-title":"Trends Cogn Sci."},{"key":"B7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1038\/npp.2010.113","article-title":"Neuroanatomical and Neurochemical Substrates of Timing","volume":"36","author":"Coull","year":"2011","journal-title":"Neuropsychopharmacol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/j.neuron.2018.03.045","article-title":"The Neural Basis of Timing: Distributed Mechanisms for Diverse Functions","volume":"98","author":"Paton","year":"2018","journal-title":"Neuron."},{"key":"B9","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1038\/nrn1764","article-title":"What makes us tick? 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