{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:01:05Z","timestamp":1792188065588,"version":"4.4.0"},"reference-count":72,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["7232289"],"award-info":[{"award-number":["7232289"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>The present study aimed to use CiteSpace to analyze the status of insomnia and circadian rhythm, identify the hot spots and trends, and provide a basis for future study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The Web of Science database was searched for studies related to insomnia and circadian from its inception to 14 April 2023. CiteSpace was used to generate online maps of collaboration between countries and authors and revealed hot spots and frontiers in insomnia and circadian rhythm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We searched 4,696 publications related to insomnia and circadian rhythm. Bruno Etain was the most prolific author with most publications, i.e., with 24 articles. The USA and the University of California were the leading country and the top institution in this field of study, with 1,672 and 269 articles, respectively. There was active cooperation between institutions, countries, and authors. Hot topics focused on circadian rhythm sleep disorders, circadian clock, light therapy, melatonin, and bipolar disorder.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Based on the CiteSpace results, we recommend a more active collaboration between various countries, institutions, and authors to conduct clinical and basic research related to insomnia and circadian rhythm. Ongoing research focuses on the interaction of insomnia with circadian rhythms and the corresponding pathways of clock genes and by extension, the role of circadian rhythms in disorders such as bipolar disorder. Modulation of circadian rhythms may be a hot spot for future insomnia therapies (such as light therapy and melatonin).<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2023.1184302","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T05:14:36Z","timestamp":1686806076000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Insomnia and circadian rhythm: a bibliometrics study and visualization analysis via CiteSpace"],"prefix":"10.3389","volume":"14","author":[{"given":"Qing-Yun","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan-Dan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,6,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"ITC33","DOI":"10.7326\/AITC202103160","article-title":"Insomnia","volume":"174","author":"Sutton","year":"2021","journal-title":"Ann Intern Med"},{"key":"B2","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/S0140-6736(22)00879-0","article-title":"Insomnia","volume":"400","author":"Perlis","year":"2022","journal-title":"Lancet."},{"key":"B3","doi-asserted-by":"publisher","first-page":"477","DOI":"10.1016\/j.sleep.2014.10.018","article-title":"Cross-cultural and comparative epidemiology of insomnia: the Diagnostic and statistical manual (DSM), international classification of diseases (ICD) and International classification of sleep disorders (ICSD)","volume":"16","author":"Chung","year":"2015","journal-title":"Sleep Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"i2123","DOI":"10.1136\/bmj.i2123","article-title":"Advances in managing chronic insomnia","volume":"354","author":"Kay-Stacey","year":"2016","journal-title":"BMJ."},{"key":"B5","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1186\/s12889-020-08483-1","article-title":"Impact of sleep problems on daytime function in school life: a cross-sectional study involving Japanese university students","volume":"20","author":"Kayaba","year":"2020","journal-title":"BMC Public Health"},{"key":"B6","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.pharmthera.2005.04.014","article-title":"Treating insomnia: current and investigational pharmacological approaches","volume":"112","author":"Ebert","year":"2006","journal-title":"Pharmacol Ther."},{"key":"B7","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1124\/pr.117.014381","article-title":"Drugs for Insomnia beyond benzodiazepines: pharmacology, clinical applications, and discovery","volume":"70","author":"Atkin","year":"2018","journal-title":"Pharmacol Rev."},{"key":"B8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/BF02246405","article-title":"Polysomnographic effects of hypnotic drugs. A review","volume":"126","author":"Parrino","year":"1996","journal-title":"Psychopharmacology."},{"key":"B9","doi-asserted-by":"publisher","first-page":"2549","DOI":"10.2147\/NDT.S297504","article-title":"Advances in the treatment of chronic insomnia: a narrative review of new nonpharmacologic and pharmacologic therapies","volume":"17","author":"Rosenberg","year":"2021","journal-title":"Neuropsychiatr Dis Treat."},{"key":"B10","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/s41573-020-00109-w","article-title":"Circadian rhythm as a therapeutic target","volume":"20","author":"Ruan","year":"2021","journal-title":"Nat Rev Drug Discov."},{"key":"B11","doi-asserted-by":"publisher","first-page":"584","DOI":"10.1210\/er.2016-1083","article-title":"Circadian rhythm and sleep disruption: causes, metabolic consequences, and countermeasures","volume":"37","author":"Potter","year":"2016","journal-title":"Endocr Rev."},{"key":"B12","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1038\/s41398-020-0694-0","article-title":"Circadian rhythm disruption and mental health","volume":"10","author":"Walker","year":"2020","journal-title":"Transl Psychiatry"},{"key":"B13","doi-asserted-by":"publisher","first-page":"549908","DOI":"10.3389\/fneur.2020.549908","article-title":"Abnormal sleep, circadian rhythm disruption, and delirium in the ICU: are they related?","volume":"11","author":"Daou","year":"2020","journal-title":"Front Neurol."},{"key":"B14","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1111\/jsr.12371","article-title":"The two-process model of sleep regulation: a reappraisal","volume":"25","author":"Borbely","year":"2016","journal-title":"J Sleep Res."},{"key":"B15","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.sleep.2019.03.009","article-title":"Sleep regularity is associated with sleep-wake and circadian timing, and mediates daytime function in delayed sleep-wake phase disorder","volume":"58","author":"Murray","year":"2019","journal-title":"Sleep Med"},{"key":"B16","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/S40037-021-00695-4","article-title":"Bibliometrics: methods for studying academic publishing","volume":"11","author":"Ninkov","year":"2022","journal-title":"Perspect Med Educ."},{"key":"B17","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1007\/BF02016680","article-title":"Toward a definition of \u201cbibliometrics\u201d","volume":"12","author":"Broadus","year":"1987","journal-title":"Scientometrics."},{"key":"B18","doi-asserted-by":"publisher","first-page":"145628","DOI":"10.1016\/j.scitotenv.2021.145628","article-title":"Trends in environmental and toxicity research on organic ultraviolet filters: a scientometric review","volume":"773","author":"Carve","year":"2021","journal-title":"Sci Total Environ."},{"key":"B19","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1002\/asi.20317","article-title":"CiteSpace II: detecting and visualizing emerging trends and transient patterns in scientific literature","volume":"57","author":"Chen","year":"2006","journal-title":"J Am Soc Inform Sci Technol"},{"key":"B20","first-page":"724","article-title":"CiteSpace II: visualization and knowledge discovery in bibliographic databases","volume":"2005","author":"Synnestvedt","year":"2005","journal-title":"AMIA Annu Symp Proc."},{"key":"B21","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1007\/s11657-021-00929-2","article-title":"Worldwide research tendency and hotspots on hip fracture: a 20-year bibliometric analysis","volume":"16","author":"Wu","year":"2021","journal-title":"Arch Osteoporos."},{"key":"B22","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1109\/TEM.2018.2870648","article-title":"A three decade mixed method bibliometric investigation of IEEE transactions on engineering management","volume":"67","author":"Marzi","year":"2018","journal-title":"IEEE Trans Eng Manag."},{"key":"B23","doi-asserted-by":"publisher","first-page":"113932","DOI":"10.1016\/j.bios.2021.113932","article-title":"Frontier and hot topics in electrochemiluminescence sensing technology based on CiteSpace bibliometric analysis","volume":"201","author":"Liu","year":"2022","journal-title":"Biosens Bioelectron"},{"key":"B24","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1038\/ng.2711","article-title":"Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs","volume":"45","author":"Lee","year":"2013","journal-title":"Nat Genet"},{"key":"B25","doi-asserted-by":"publisher","first-page":"101439","DOI":"10.1016\/j.smrv.2021.101439","article-title":"A systematic analysis of ICSD-3 diagnostic criteria and proposal for further structured iteration","volume":"58","author":"Gauld","year":"2021","journal-title":"Sleep Med Rev"},{"key":"B26","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.smrv.2015.06.004","article-title":"The etiology of delayed sleep phase disorder","volume":"27","author":"Micic","year":"2016","journal-title":"Sleep Med Rev."},{"key":"B27","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1093\/sleep\/33.12.1605","article-title":"The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis","volume":"33","author":"van Geijlswijk","year":"2010","journal-title":"Sleep."},{"key":"B28","doi-asserted-by":"publisher","first-page":"933690","DOI":"10.3389\/fpsyt.2022.933690","article-title":"Altered distribution of resting periods of daily locomotor activity in patients with delayed sleep phase disorder","volume":"13","author":"Hirose","year":"2022","journal-title":"Front Psychiatry"},{"key":"B29","doi-asserted-by":"publisher","first-page":"1062","DOI":"10.1038\/12502","article-title":"Familial advanced sleep-phase syndrome: a short-period circadian rhythm variant in humans","volume":"5","author":"Jones","year":"1999","journal-title":"Nat Med"},{"key":"B30","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1038\/nature03453","article-title":"Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome","volume":"434","author":"Xu","year":"2005","journal-title":"Nature"},{"key":"B31","doi-asserted-by":"publisher","first-page":"2660","DOI":"10.1101\/gad.397006","article-title":"Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)","volume":"20","author":"Vanselow","year":"2006","journal-title":"Genes Dev"},{"key":"B32","doi-asserted-by":"publisher","first-page":"1424","DOI":"10.3390\/pharmaceutics14071424","article-title":"An overview of the circadian clock in the frame of chronotherapy: from bench to bedside","volume":"14","author":"Vandenberghe","year":"2022","journal-title":"Pharmaceutics"},{"key":"B33","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.cell.2017.03.027","article-title":"Mutation of the human circadian clock gene CRY1 in familial delayed sleep phase disorder","volume":"169","author":"Patke","year":"2017","journal-title":"Cell"},{"key":"B34","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1093\/embo-reports\/kve070","article-title":"Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome","volume":"2","author":"Ebisawa","year":"2001","journal-title":"EMBO Rep"},{"key":"B35","doi-asserted-by":"publisher","first-page":"e16695","DOI":"10.7554\/eLife.16695","article-title":"A cryptochrome 2 mutation yields advanced sleep phase in humans","volume":"5","author":"Hirano","year":"2016","journal-title":"Elife"},{"key":"B36","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/nature11048","article-title":"Regulation of circadian behaviour and metabolism by REV-ERB-alpha and REV-ERB-beta","volume":"485","author":"Cho","year":"2012","journal-title":"Nature"},{"key":"B37","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1038\/nsmb925","article-title":"The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1","volume":"12","author":"Akashi","year":"2005","journal-title":"Nat Struct Mol Biol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1038\/nature00906","article-title":"A transcription factor response element for gene expression during circadian night","volume":"418","author":"Ueda","year":"2002","journal-title":"Nature"},{"key":"B39","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/S0092-8674(02)00825-5","article-title":"The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator","volume":"110","author":"Preitner","year":"2002","journal-title":"Cell"},{"key":"B40","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1126\/science.1226339","article-title":"Transcriptional architecture and chromatin landscape of the core circadian clock in mammals","volume":"338","author":"Koike","year":"2012","journal-title":"Science"},{"key":"B41","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1038\/ng1738","article-title":"Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions","volume":"38","author":"Ripperger","year":"2006","journal-title":"Nat Genet."},{"key":"B42","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1080\/07853890701491034","article-title":"Physiological function of PARbZip circadian clock-controlled transcription factors","volume":"39","author":"Gachon","year":"2007","journal-title":"Ann Med."},{"key":"B43","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1038\/nature01123","article-title":"Dec1 and Dec2 are regulators of the mammalian molecular clock","volume":"419","author":"Honma","year":"2002","journal-title":"Nature"},{"key":"B44","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1038\/419798a","article-title":"Circadian rhythms: finer clock control","volume":"419","author":"Alvarez","year":"2002","journal-title":"Nature."},{"key":"B45","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1126\/science.1174443","article-title":"The transcriptional repressor DEC2 regulates sleep length in mammals","volume":"325","author":"He","year":"2009","journal-title":"Science"},{"key":"B46","doi-asserted-by":"publisher","first-page":"1044","DOI":"10.1016\/j.neuron.2019.07.026","article-title":"A rare mutation of beta(1)-adrenergic receptor affects sleep\/wake behaviors","volume":"103","author":"Shi","year":"2019","journal-title":"Neuron"},{"key":"B47","doi-asserted-by":"publisher","first-page":"eaax2014","DOI":"10.1126\/scitranslmed.aax2014","article-title":"Mutant neuropeptide S receptor reduces sleep duration with preserved memory consolidation","volume":"11","author":"Xing","year":"2019","journal-title":"Sci Transl Med"},{"key":"B48","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1093\/sleep\/16.5.436","article-title":"The effect of evening bright light in delaying the circadian rhythms and lengthening the sleep of early morning awakening insomniacs","volume":"16","author":"Lack","year":"1993","journal-title":"Sleep."},{"key":"B49","doi-asserted-by":"publisher","first-page":"625431","DOI":"10.3389\/fneur.2021.625431","article-title":"Daily morning blue light therapy for Post-mTBI sleep disruption: effects on brain structure and function","volume":"12","author":"Raikes","year":"2021","journal-title":"Front Neurol."},{"key":"B50","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.cger.2007.08.013","article-title":"Light therapy for insomnia in older adults","volume":"24","author":"Gammack","year":"2008","journal-title":"Clin Geriatr Med"},{"key":"B51","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2147\/NSS.S344616","article-title":"The clinical effect of blue light therapy on patients with delayed sleep-wake phase disorder","volume":"14","author":"Li","year":"2022","journal-title":"Nat Sci Sleep"},{"key":"B52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/S0033291722002616","article-title":"Treating postpartum insomnia: a three arm randomised controlled trial of cognitive behavioural therapy and light dark therapy","author":"Verma","year":"2022","journal-title":"Psychol Med"},{"key":"B53","doi-asserted-by":"publisher","first-page":"106877","DOI":"10.1016\/j.cct.2022.106877","article-title":"The sleep, cancer and rest (SleepCaRe) trial: rationale and design of a randomized, controlled trial of cognitive behavioral and bright light therapy for insomnia and fatigue in women with breast cancer receiving chemotherapy","volume":"120","author":"Maccora","year":"2022","journal-title":"Contemp Clin Trials"},{"key":"B54","doi-asserted-by":"publisher","first-page":"zsw038","DOI":"10.1093\/sleep\/zsw038","article-title":"Effects of melatonin and bright light treatment in childhood chronic sleep onset insomnia with late melatonin onset: a randomized controlled study","volume":"40","author":"van Maanen","year":"2017","journal-title":"Sleep"},{"key":"B55","doi-asserted-by":"publisher","first-page":"469","DOI":"10.4088\/JCP.v66n0409","article-title":"A review of the evidence for the efficacy and safety of trazodone in insomnia","volume":"66","author":"Mendelson","year":"2005","journal-title":"J Clin Psychiatry."},{"key":"B56","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1016\/j.smrv.2004.02.001","article-title":"Residual effects of sleep medication on driving ability","volume":"8","author":"Verster","year":"2004","journal-title":"Sleep Med Rev."},{"key":"B57","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1017\/S1092852900019611","article-title":"Light therapy for seasonal and nonseasonal depression: efficacy, protocol, safety, and side effects","volume":"10","author":"Terman","year":"2005","journal-title":"CNS Spectr"},{"key":"B58","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1055\/s-0031-1296459","article-title":"Melatonergic drugs in clinical practice","volume":"58","author":"Hardeland","year":"2008","journal-title":"Arzneimittelforschung."},{"key":"B59","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.5664\/jcsm.26932","article-title":"Melatonin and its receptors: a new class of sleep-promoting agents","volume":"3","author":"Doghramji","year":"2007","journal-title":"J Clin Sleep Med."},{"key":"B60","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1007\/s00441-019-03033-7","article-title":"Circadian neurogenetics of mood disorders","volume":"377","author":"Mendoza","year":"2019","journal-title":"Cell Tissue Res."},{"key":"B61","doi-asserted-by":"publisher","first-page":"1561","DOI":"10.1016\/S0140-6736(15)00241-X","article-title":"Bipolar disorder","volume":"387","author":"Grande","year":"2016","journal-title":"Lancet."},{"key":"B62","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/j.jad.2014.09.003","article-title":"Risk factors for suicide in bipolar disorder: a systematic review","volume":"170","author":"Costa Lda","year":"2015","journal-title":"J Affect Disord."},{"key":"B63","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1038\/s41588-019-0397-8","article-title":"Genome-wide association study identifies 30 loci associated with bipolar disorder","volume":"51","author":"Stahl","year":"2019","journal-title":"Nat Genet"},{"key":"B64","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1176\/appi.ajp.2008.08010098","article-title":"Sleep and circadian rhythms in bipolar disorder: seeking synchrony, harmony, and regulation","volume":"165","author":"Harvey","year":"2008","journal-title":"Am J Psychiatry."},{"key":"B65","doi-asserted-by":"publisher","first-page":"2325","DOI":"10.2147\/NDT.S73765","article-title":"Association of Per3 length polymorphism with bipolar I disorder and schizophrenia","volume":"10","author":"Karthikeyan","year":"2014","journal-title":"Neuropsychiatr Dis Treat"},{"key":"B66","doi-asserted-by":"publisher","first-page":"1399","DOI":"10.1007\/s11325-015-1229-4","article-title":"A cross-sectional study on the relationships among the polymorphism of period2 gene, work stress, and insomnia","volume":"19","author":"Li","year":"2015","journal-title":"Sleep Breath."},{"key":"B67","doi-asserted-by":"publisher","first-page":"807","DOI":"10.3109\/07420528.2014.906445","article-title":"Association between circadian genes, bipolar disorders and chronotypes","volume":"31","author":"Etain","year":"2014","journal-title":"Chronobiol Int"},{"key":"B68","doi-asserted-by":"publisher","first-page":"561","DOI":"10.3109\/07420528.2016.1167078","article-title":"Circadian gene variants influence sleep and the sleep electroencephalogram in humans","volume":"33","author":"Chang","year":"2016","journal-title":"Chronobiol Int"},{"key":"B69","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1007\/s11920-019-1001-8","article-title":"Treating circadian rhythm disruption in bipolar disorder","volume":"21","author":"Gold","year":"2019","journal-title":"Curr Psychiatry Rep."},{"key":"B70","doi-asserted-by":"publisher","first-page":"16m11027","DOI":"10.4088\/JCP.16m11027","article-title":"Psychotherapy alone and combined with medication as treatments for bipolar II depression: a randomized controlled trial","volume":"79","author":"Swartz","year":"2018","journal-title":"J Clin Psychiatry"},{"key":"B71","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1111\/bdi.12390","article-title":"Blue-blocking glasses as additive treatment for mania: a randomized placebo-controlled trial","volume":"18","author":"Henriksen","year":"2016","journal-title":"Bipolar Disord"},{"key":"B72","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1177\/0748730410362713","article-title":"Nuclear receptor rev-erb-alpha circadian gene variants and lithium carbonate prophylaxis in bipolar affective disorder","volume":"25","author":"Campos-de-Sousa","year":"2010","journal-title":"J Biol Rhythms"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2023.1184302\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T05:14:39Z","timestamp":1686806079000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2023.1184302\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,15]]},"references-count":72,"alternative-id":["10.3389\/fneur.2023.1184302"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2023.1184302","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,15]]},"article-number":"1184302"}}