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Although the mechanism of cerebrovascular complications among COVID-19 patients has not been adequately elucidated, the hypercoagulable state, excessive inflammation and ACE-2-associated alterations in the renin-angiotensin-aldosterone system after SARS-CoV-2 infection probably play an essential role. In this overview, we discuss the possible mechanisms underlying the SARS-CoV-2 infection leading to acute cerebrovascular events and review the characteristics of COVID-19-related acute cerebrovascular events cases and treatment options available worldwide.<\/jats:p>","DOI":"10.3389\/fneur.2023.1216978","type":"journal-article","created":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T10:03:24Z","timestamp":1687946604000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Coronavirus disease 2019 and acute cerebrovascular events: a comprehensive 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