{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T08:27:37Z","timestamp":1768638457293,"version":"3.49.0"},"reference-count":23,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,11,9]],"date-time":"2023-11-09T00:00:00Z","timestamp":1699488000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>IgG4-related or IgG4-associated hypophysitis is a rare disease characterized by the infiltration of IgG4-positive plasma cells into pituitary gland tissue. Gangliocytomas in the sellar region are also extremely rare and are associated with pituitary adenomas in the majority of cases. Sellar mucosa-associated lymphoid tissue (MALT) lymphoma is an exceedingly rare condition. In this study, we present a case of IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma. However, to elucidate the potential pathophysiological relationship, it is imperative to gather additional cases of IgG4-related hypophysitis accompanied by MALT lymphoma and gangliocytoma.<\/jats:p>","DOI":"10.3389\/fneur.2023.1253821","type":"journal-article","created":{"date-parts":[[2023,11,13]],"date-time":"2023-11-13T04:26:40Z","timestamp":1699849600000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["IgG4-associated hypophysitis coexisting with MALT lymphoma and gangliocytoma: first case report and literature review"],"prefix":"10.3389","volume":"14","author":[{"given":"Dongbo","family":"Zou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingmin","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,11,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"104016","DOI":"10.1016\/j.lpm.2020.104016","article-title":"IgG4 hypophysitis: diagnosis and management","volume":"49","author":"Lojou","year":"2020","journal-title":"Presse Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"m1067","DOI":"10.1136\/bmj.m1067","article-title":"Advances in the diagnosis and management of IgG4 related disease","volume":"369","author":"Lanzillotta","year":"2020","journal-title":"BMJ"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/S1474-4422(17)30471-4","article-title":"IgG4-related disease of the central and peripheral nervous systems","volume":"17","author":"AbdelRazek","year":"2018","journal-title":"Lancet Neurol"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1971","DOI":"10.1210\/jc.2010-2970","article-title":"IgG4-related hypophysitis: a new addition to the hypophysitis spectrum","volume":"96","author":"Leporati","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1097\/PAS.0000000000000806","article-title":"Mixed gangliocytoma-pituitary adenoma: insights on the pathogenesis of a rare sellar tumor","volume":"41","author":"Lopes","year":"2017","journal-title":"Am J Surg Pathol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1111\/epi.13752","article-title":"Hypothalamic hamartoma: neuropathology and epileptogenesis","volume":"58","author":"Kerrigan","year":"2017","journal-title":"Epilepsia"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1002\/art.39132","article-title":"International consensus guidance statement on the management and treatment of IgG4-related disease","volume":"67","author":"Khosroshahi","year":"2015","journal-title":"Arthritis Rheum"},{"key":"ref8","first-page":"961","article-title":"Amendment of the Japanese consensus guidelines for autoimmune pancreatitis, 2013 III. 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