{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T23:58:51Z","timestamp":1769817531704,"version":"3.49.0"},"reference-count":37,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T00:00:00Z","timestamp":1701734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82071313"],"award-info":[{"award-number":["82071313"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Background and purpose<\/jats:title><jats:p>To study the changes of corticocerebral hemodynamics in surgical area and postoperative hyperperfusion syndrome in patients with chronic internal carotid artery occlusion (CICAO) by intraoperative indocyanine green videoangiography (ICGA)-FLOW 800 and CT perfusion after superficial temporal artery (STA)\u2013middle cerebral artery (MCA) bypass surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From October 2019 to January 2021, 77 patients diagnosed with CICAO underwent direct bypass surgery at Huadong hospital (affiliated with Fudan University) were enrolled. Regions of interest (ROIs) at STA, proximal MCA (PMCA), distal MCA (DMCA), cortical blood capillary (CBC), and cortical vein (CV) were identified after anastomosis by ICGV-FLOW 800 including peak fluorescence intensity (PFI), time to peak (TTP), and area under the time curve (AUC) of fluorescence intensity. All patients underwent perfusion-weighted CT before bypass surgery and those patients with HPS were verified by CTP after bypass.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>14 patients with HPS were verified by perfusion-weighted CT after bypass. In HPS group, the AUC<jats:sub>TTP<\/jats:sub> of DMCA was significantly larger (T\u2009=\u2009\u22123.301, <jats:italic>p<\/jats:italic>\u2009=\u20090.004) and TTP of CBC was shorter (T\u2009=\u2009\u22122.929, <jats:italic>p<\/jats:italic>\u2009=\u20090.005) than patients in non-HPS group. The larger AUC<jats:sub>TTP<\/jats:sub> of DMCA (OR\u2009=\u20093.024, 95%CI 1.390\u20136.578, <jats:italic>p<\/jats:italic>\u2009=\u20090.0050) was an independent risk factor by further multivariate logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The hemodynamic changes of cortical vessels during STA-MCA bypass surgery could be recorded accurately by ICGV-FLOW 800. Furthermore, the increased AUC<jats:sub>TTP<\/jats:sub> of DMCA and shorter TTP of CBC may be potential risk factors of HPS.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2023.1323626","type":"journal-article","created":{"date-parts":[[2023,12,5]],"date-time":"2023-12-05T11:05:06Z","timestamp":1701774306000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Combination of intraoperative indocyanine green video-angiography FLOW 800 and computed tomography perfusion to assess the risk of cerebral hyperperfusion syndrome in chronic internal carotid artery occlusion patients after revascularization surgery"],"prefix":"10.3389","volume":"14","author":[{"given":"Juan","family":"Du","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fayong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renling","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinghua","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,12,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"733","DOI":"10.1177\/1708538120978043","article-title":"Chronic total occlusion and spontaneous recanalization of the internal carotid artery: natural history and management strategy","volume":"29","author":"Lall","year":"2021","journal-title":"Vascular"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s13760-019-01165-9","article-title":"Cerebrovascular events after surgery versus conservative therapy for moyamoya disease: a meta-analysis","volume":"119","author":"Wouters","year":"2019","journal-title":"Acta Neurol Belg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1136\/neurintsurg-2019-015621","article-title":"Update on cerebral hyperperfusion syndrome","volume":"12","author":"Lin","year":"2020","journal-title":"J Neurointerv Surg"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"107222","DOI":"10.1016\/j.jstrokecerebrovasdis.2023.107222","article-title":"Hyperperfusion syndrome after superficial temporal artery-middle cerebral artery bypass for non-moyamoya steno-occlusive disease","volume":"32","author":"Turpin","year":"2023","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"e187","DOI":"10.1016\/j.wneu.2018.04.148","article-title":"Quantitative blood flow assessment by multiparameter analysis of indocyanine green video angiography","volume":"116","author":"Saito","year":"2018","journal-title":"World Neurosurg"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1001\/archneur.1969.00480090076012","article-title":"Cerebrovascular \"moyamoya\" disease. Disease showing abnormal net-like vessels in base of brain","volume":"20","author":"Suzuki","year":"1969","journal-title":"Arch Neurol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1159\/000511307","article-title":"Cerebral Hyperperfusion syndrome and related conditions","volume":"83","author":"Delgado","year":"2020","journal-title":"Eur Neurol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1136\/jnnp.2010.208330","article-title":"Symptomatic internal carotid artery occlusion: a long-term follow-up study","volume":"82","author":"Persoon","year":"2011","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1186\/s13063-016-1600-1","article-title":"The carotid and middle cerebral artery occlusion surgery study (CMOSS): a study protocol for a randomised controlled 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N-isopropyl-p-(123)Iiodoamphetamine single-photon emission computed tomography","volume":"68","author":"Fujimura","year":"2011","journal-title":"Neurosurgery"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3171\/2017.10.JNS171749","article-title":"Risk factors for and outcomes of postoperative complications in adult patients with moyamoya disease","volume":"1","author":"Zhao","year":"2018","journal-title":"J Neurosurg"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1159\/000336765","article-title":"Efficacy of prophylactic blood pressure lowering according to a standardized postoperative management protocol to prevent symptomatic cerebral hyperperfusion after direct revascularization surgery for moyamoya disease","volume":"33","author":"Fujimura","year":"2012","journal-title":"Cerebrovasc Dis"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1716","DOI":"10.3171\/2018.7.JNS18149","article-title":"Impact of cerebral blood 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