{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:05:07Z","timestamp":1753891507309,"version":"3.41.2"},"reference-count":16,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T00:00:00Z","timestamp":1703030400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>Occlusion of an intracranial arterial branch, resulting in a false positive aneurysm on vascular imaging, is extremely rare, with only a few reports in the literature and mostly in the posterior circulation artery or the middle cerebral artery (MCA) bifurcation. We report a case of a 69\u2009years-old woman with a subacute infarct lesion in the left frontal lobe, for whom both computed tomographic angiography (CTA) and digital subtraction angiography (DSA) of the cerebral vessels showed aneurysms in the anterior segment of the M1 bifurcation of the middle cerebral artery (MCA) and in the bifurcation of the MCA. The aneurysm in the MCA bifurcation was found during craniotomy, whereas the anterior segment of the M1 bifurcation had intact branch vessels with severe atherosclerosis and no aneurysm was present. The branch vessel of M1 was presumed to be atherosclerotic occlusion resulting in the distal vessels without contrast filling on CTA and DSA, and only the occluded stump at the beginning of the vessel was filled with contrast, showing an aneurysm-like morphology, which was very confusing. This case highlights to neurologists that the diagnosis of aneurysm by cerebrovascular CTA or DSA must be carefully differentiated to avoid misdiagnosis, especially if the unruptured aneurysm is in an uncommon location in combination with ischemic cerebrovascular disease.<\/jats:p>","DOI":"10.3389\/fneur.2023.1327878","type":"journal-article","created":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T09:04:09Z","timestamp":1703063049000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["False positive angiographic aneurysm of the anterior segment of the M1 bifurcation of the middle cerebral artery: a case report"],"prefix":"10.3389","volume":"14","author":[{"given":"Wen","family":"Xiao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaolin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dingjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongdong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2023,12,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"413","DOI":"10.3340\/jkns.2007.42.5.413","article-title":"Occlusion of the middle cerebral artery branch mimicking aneurysm","volume":"42","author":"Lee","year":"2007","journal-title":"J Korean Neurosurg Soc"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/j.surneu.2007.06.036","article-title":"Occluded vascular stump mimicking middle cerebral artery bifurcation aneurysm: report of 2 cases","volume":"70","author":"Park","year":"2008","journal-title":"Surg Neurol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"869","DOI":"10.12669\/pjms.293.2839","article-title":"Occluded middle cerebral artery vascular stump mimicking aneurysm: case report and review of literature","volume":"29","author":"Yu","year":"2013","journal-title":"Pak J Med Sci"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"e0230754","DOI":"10.1371\/journal.pone.0230754","article-title":"A new simple brain segmentation method for extracerebral intracranial tumors","volume":"15","author":"Hou","year":"2020","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/S1474-4422(11)70109-0","article-title":"Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis","volume":"10","author":"Vlak","year":"2011","journal-title":"Lancet Neurol"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1136\/jnnp-2020-324418","article-title":"Prevalence, predictors and prognosis of incidental intracranial aneurysms in patients with suspected TIA and minor stroke: a population-based study and systematic review","volume":"92","author":"Hurford","year":"2021","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1227\/NEU.0000000000000562","article-title":"Endovascular treatment of 346 middle cerebral artery aneurysms: results of a 16\u2009years single-center experience","volume":"76","author":"Kadkhodayan","year":"2015","journal-title":"Neurosurgery"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1093\/neuros\/nyx623","article-title":"Coiling versus microsurgical clipping in the treatment of unruptured middle cerebral artery aneurysms: a meta-analysis","volume":"83","author":"Alreshidi","year":"2018","journal-title":"Neurosurgery"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1161\/STROKEAHA.113.003133","article-title":"Diagnosing intracranial aneurysms with MR angiography: systematic review and meta-analysis","volume":"45","author":"Sailer","year":"2014","journal-title":"Stroke"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"941","DOI":"10.1148\/radiol.2017162290","article-title":"Small intracranial aneurysms: diagnostic accuracy of CT angiography","volume":"285","author":"Yang","year":"2017","journal-title":"Radiology"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1177\/159101991101700206","article-title":"Angiographic pitfall: duplicated tapered A1 segment of the anterior cerebral artery mimicking an anterior communicating artery aneurysm","volume":"17","author":"Weil","year":"2011","journal-title":"Interv Neuroradiol"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.3171\/JNS.2008.109.12.1123","article-title":"Middle cerebral artery branch occlusion mimicking a saccular aneurysm on 3D digital subtraction angiography","volume":"109","author":"Pearl","year":"2008","journal-title":"J Neurosurg"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"117","DOI":"10.4103\/1793-5482.144155","article-title":"Middle cerebral artery branch occlusion mimicking an aneurysm","volume":"10","author":"Takeuchi","year":"2015","journal-title":"Asian J Neurosurg"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"805","DOI":"10.2176\/nmc.tn.2014-0439","article-title":"3D-FIESTA magnetic resonance angiography fusion imaging of distal segment of occluded middle cerebral artery","volume":"55","author":"Kuribara","year":"2015","journal-title":"Neurol Med Chir"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"452","DOI":"10.5797\/jnet.oa.2021-0102","article-title":"3D T2-weighted sampling perfection with application-optimized contrasts using different flip angle evolutions (SPACE) and 3D time-of-flight (TOF) MR angiography fusion imaging for occluded intracranial arteries","volume":"16","author":"Ozaki","year":"2022","journal-title":"J Neuroendovasc Ther"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.nic.2021.01.005","article-title":"High-resolution magnetic resonance vessel wall imaging for the evaluation of intracranial vascular pathology","volume":"31","author":"Vranic","year":"2021","journal-title":"Neuroimaging Clin N Am"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2023.1327878\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,20]],"date-time":"2023-12-20T09:04:12Z","timestamp":1703063052000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2023.1327878\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,20]]},"references-count":16,"alternative-id":["10.3389\/fneur.2023.1327878"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2023.1327878","relation":{},"ISSN":["1664-2295"],"issn-type":[{"type":"electronic","value":"1664-2295"}],"subject":[],"published":{"date-parts":[[2023,12,20]]},"article-number":"1327878"}}