{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:50:08Z","timestamp":1793321408897,"version":"4.5.0"},"reference-count":35,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T00:00:00Z","timestamp":1709164800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Background and purpose<\/jats:title>\n                    <jats:p>Customized vestibular rehabilitation improved dizziness and imbalance in several randomized controlled trials. In the present study, we determined the efficacy of customized vestibular rehabilitation using real-world observational data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective observational study, we recruited 64 patients (median age\u2009=\u200960, interquartile range\u2009=\u200948\u201366.3) who completed the customized vestibular rehabilitation from January to December 2022. The outcomes of rehabilitation were evaluated using the dizziness handicap inventory (DHI) or vestibular disorders activities of daily living scale (VADL). The factors associated with outcomes were assessed with a generalized linear model, of which covariates included patients\u2019 age, sex, duration of illness, type of vestibular disorders, initial DHI and VADL scores, exercise compliance, and initial hospital anxiety and depression scale (HADS) scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After the median of 6 (4\u20136) weeks of rehabilitation, DHI and VADL scores significantly improved in patients with either peripheral or central vestibular disorders (Wilcoxon signed-rank test,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&amp;lt;\u20090.05). The initial DHI and VADL scores showed a positive while the sum of HADS scores showed a negative correlation with the outcome. In contrast, the age, sex, duration of illness, types of vestibular disorders, and exercise compliance did not affect the outcome.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion and conclusion<\/jats:title>\n                    <jats:p>Customized vestibular rehabilitation is effective for central as well as peripheral disorders, especially when the symptoms are severe and the psychological distress is mild.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2024.1329418","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T08:33:04Z","timestamp":1709195584000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":16,"title":["Efficacy of vestibular rehabilitation and its facilitating and hindering factors from real-world clinical data"],"prefix":"10.3389","volume":"15","author":[{"given":"Min-Ku","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"So-Yeon","family":"Yun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seonkyung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ja-Ok","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soo-Yun","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ju-Young","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo-Jung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hye Youn","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong-Yoon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Jin","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Yoon","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ja-Won","family":"Koo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,2,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s00415-020-10228-4","article-title":"Vestibular rehabilitation in Europe: a survey of clinical and research practice","volume":"267","author":"Meldrum","year":"2020","journal-title":"J Neurol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"184","DOI":"10.3988\/jcn.2011.7.4.184","article-title":"Vestibular rehabilitation therapy: review of indications, mechanisms, and key exercises","volume":"7","author":"Han","year":"2011","journal-title":"J Clin Neurol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1097\/NPT.0000000000000120","article-title":"Vestibular rehabilitation for peripheral vestibular hypofunction: an evidence-based clinical practice guideline: from the American Physical Therapy Association neurology section","volume":"40","author":"Hall","year":"2016","journal-title":"J Neurol Phys Ther"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"CD005397","DOI":"10.1002\/14651858.CD005397.pub4","article-title":"Vestibular rehabilitation for unilateral peripheral vestibular dysfunction","volume":"1","author":"McDonnell","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"283","DOI":"10.3233\/VES-120464","article-title":"The effect of vestibular rehabilitation on adults with bilateral vestibular hypofunction: a systematic review","volume":"22","author":"Porciuncula","year":"2012","journal-title":"J Vestib Res"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1097\/MAO.0000000000002443","article-title":"Efficacy of vestibular rehabilitation following acute vestibular neuritis: a randomized controlled trial","volume":"41","author":"Tokle","year":"2020","journal-title":"Otol Neurotol"},{"key":"ref7","first-page":"1","article-title":"Vestibular rehabilitation following the removal of an acoustic neuroma: a systematic review of randomized trials","volume":"4","author":"Passier","year":"2012","journal-title":"Head Neck Oncol"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"442","DOI":"10.1136\/bjsports-2016-096081","article-title":"Can vestibular rehabilitation exercises help patients with concussion? 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