{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T02:46:59Z","timestamp":1789958819767,"version":"4.0.1"},"reference-count":40,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T00:00:00Z","timestamp":1713312000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Low Back Pain (LBP) is a pervasive and complex musculoskeletal condition affecting over 80% of the global population. Lumbar Disc Degeneration (LDD) significantly contributes to LBP, and MRI is crucial for its diagnosis and understanding. This study aimes to provide a comprehensive bibliometric analysis of MRI research on LDD with LBP, shedding light on research patterns, collaborations, and potential knowledge gaps.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A comprehensive online search was conducted in the Scopus database to retrieve published literature on LDD with LBP. Bibliometric analysis was conducted to assess publication patterns, co-authorship networks, keyword co-occurrence, and co-citation analysis within the MRI applications for LDD research domain. Bibliometric analysis tools such as VOSviewer and the R package \u201cbibliometrix\u201d were utilized for quantitative assessments.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 1,619 publications related to MRI and LDD were analyzed. The analysis indicated a consistent annual growth rate of 4.62% in publications related to MRI and lumbar disc degeneration, reflecting a steady increase in research output over the past two decades. The USA, China, and Japan emerged as leading contributors. \u201cSPINE\u201c, \u201cEuropean Spine Journal\u201c, and \u201cSpine Journal\u201d were the most productive journals in this domain. Key research themes identified included lumbar spine, low back pain, and magnetic resonance imaging. Network visualization shows that low back pain and magnetic resonance imaging were the most widely used keywords.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The comprehensive bibliometric analysis of MRI applications for Lumbar Disc Degeneration offers insights into prevailing research patterns, highlights key contributors and journals, and identifies significant research themes. This study provides a foundation for future research efforts and clinical practices in the field, ultimately contributing to the advancement of patient care for individuals suffering from LDD and associated Low Back Pain.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2024.1360091","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T04:56:11Z","timestamp":1713329771000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Research trend of MRI application for lumbar disc degeneration with low back pain: a bibliometric analysis"],"prefix":"10.3389","volume":"15","author":[{"given":"Azzam","family":"Saeed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyue","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal","family":"Hezam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoxu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiya","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,4,17]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1016\/S0140-6736(18)32279-7","article-title":"Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"392","year":"2018","journal-title":"Lancet."},{"key":"B2","doi-asserted-by":"publisher","first-page":"e316","DOI":"10.1016\/S2665-9913(23)00098-X","article-title":"Global, Regional, and national burden of low back pain, 1990-2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021","volume":"5","author":"GBD","year":"2023","journal-title":"Lancet Rheumatol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1891","DOI":"10.1056\/NEJMcp042054","article-title":"Clinical practice. Persistent low back pain","volume":"352","author":"Carragee","year":"2005","journal-title":"N Engl J Med."},{"key":"B4","doi-asserted-by":"publisher","first-page":"2151","DOI":"10.1097\/01.brs.0000231761.73859.2c","article-title":"What Is intervertebral disc degeneration, and what causes it?","volume":"31","author":"Adams","year":"2006","journal-title":"Spine (Phila Pa 1976)"},{"key":"B5","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1186\/ar629","article-title":"Degeneration of the Intervertebral Disc","volume":"5","author":"Urban","year":"2003","journal-title":"Arthritis Res Ther."},{"key":"B6","doi-asserted-by":"publisher","first-page":"2679","DOI":"10.1097\/01.brs.0000146457.83240.eb","article-title":"Lumbar disc degeneration: epidemiology and genetic influences","volume":"29","author":"Batti\u00e9","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"key":"B7","doi-asserted-by":"publisher","first-page":"662","DOI":"10.2106\/JBJS.I.01568","article-title":"Population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status","volume":"93","author":"Samartzis","year":"2011","journal-title":"J Bone Joint Surg Am."},{"key":"B8","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2106\/JBJS.E.01273","article-title":"Lumbar disc disorders and low-back pain: socioeconomic factors and consequences","volume":"2","author":"Katz","year":"2006","journal-title":"J Bone Joint Surg Am."},{"key":"B9","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1148\/radiol.2451051706","article-title":"Lumbar degenerative disk disease","volume":"245","author":"Modic","year":"2007","journal-title":"Radiology."},{"key":"B10","doi-asserted-by":"publisher","first-page":"420","DOI":"10.3390\/diagnostics12020420","article-title":"Novel magnetic resonance imaging tools for the diagnosis of degenerative disc disease: a narrative review","volume":"12","author":"Mallio","year":"2022","journal-title":"Diagnostics (Basel)"},{"key":"B11","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1097\/BRS.0b013e3181a01b3f","article-title":"Prevalence and pattern of lumbar magnetic resonance imaging changes in a population study of one thousand forty-three individuals","volume":"34","author":"Cheung","year":"2009","journal-title":"Spine (Phila Pa 1976)"},{"key":"B12","doi-asserted-by":"publisher","first-page":"2271","DOI":"10.1097\/00007632-199311000-00022","article-title":"Topographic differences of 1h-nmr relaxation times (T1, T2) in the normal intervertebral disc and its relationship to water content","volume":"18","author":"Chatani","year":"1993","journal-title":"Spine (Phila Pa 1976)"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2023.05.011","article-title":"Innovative quantitative magnetic resonance tools to detect early intervertebral disc degeneration changes: a systematic review","author":"Russo","year":"2023","journal-title":"Spine J."},{"key":"B14","doi-asserted-by":"publisher","first-page":"744","DOI":"10.21037\/qims.2016.12.09","article-title":"Quantitative magnetic resonance imaging of the lumbar intervertebral discs","volume":"6","author":"Hwang","year":"2016","journal-title":"Quant Imaging Med Surg."},{"key":"B15","doi-asserted-by":"publisher","first-page":"108858","DOI":"10.1016\/j.ejrad.2020.108858","article-title":"Quantitative synthetic mri for evaluation of the lumbar intervertebral disk degeneration in patients with chronic low back pain","volume":"124","author":"Jiang","year":"2020","journal-title":"Eur J Radiol."},{"key":"B16","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s11916-007-0186-4","article-title":"Potential clinical applications for spinal functional MRI","volume":"11","author":"Kornelsen","year":"2007","journal-title":"Curr Pain Headache Rep."},{"key":"B17","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.rbmo.2012.03.007","article-title":"The uses and abuses of bibliometrics","volume":"24","author":"Johnson","year":"2012","journal-title":"Reprod Biomed Online."},{"key":"B18","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1478-4505-12-26","article-title":"Scientometric trends and knowledge maps of global health systems research health","volume":"12","author":"Yao","year":"2014","journal-title":"Res Policy Syst."},{"key":"B19","doi-asserted-by":"publisher","first-page":"1809","DOI":"10.1007\/s11192-015-1645-z","article-title":"The bibliometric analysis of scholarly production: how great is the impact?","volume":"105","author":"Ellegaard","year":"2015","journal-title":"Scientometrics."},{"key":"B20","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1016\/S0140-6736(09)60172-0","article-title":"Imaging strategies for low-back pain: systematic review and meta-analysis","volume":"373","author":"Chou","year":"2009","journal-title":"Lancet."},{"key":"B21","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.joca.2013.10.019","article-title":"Prevalence and distribution of intervertebral disc degeneration over the entire spine in a population-based cohort: the wakayama spine study","volume":"22","author":"Teraguchi","year":"2014","journal-title":"Osteoarthritis Cartilage."},{"key":"B22","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1007\/s11192-009-0146-3","article-title":"Software survey: vosviewer, a computer program for bibliometric mapping","volume":"84","author":"van Eck","year":"2010","journal-title":"Scientometrics."},{"key":"B23","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1016\/j.joi.2017.08.007","article-title":"Bibliometrix: an R-tool for comprehensive science mapping analysis","volume":"11","author":"Aria","year":"2017","journal-title":"J Informetr."},{"key":"B24","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1097\/00007632-200002150-00016","article-title":"Low back pain in relation to lumbar disc degeneration","volume":"25","author":"Luoma","year":"2000","journal-title":"Spine (Phila Pa 1976)"},{"key":"B25","doi-asserted-by":"publisher","first-page":"1306","DOI":"10.2106\/00004623-200109000-00002","article-title":"The value of magnetic resonance imaging of the lumbar spine to predict low-back pain in asymptomatic subjects: a seven-year follow-up study","volume":"83","author":"Borenstein","year":"2001","journal-title":"JBJS"},{"key":"B26","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1097\/01.brs.0000162396.97739.76","article-title":"Magnetic resonance imaging and low back pain in adults: a diagnostic imaging study of 40-year-old men and women","volume":"30","author":"Kjaer","year":"2005","journal-title":"Spine"},{"key":"B27","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1053\/crad.1999.0340","article-title":"Correlation between the MRI changes in the lumbar multifidus muscles and leg pain","volume":"55","author":"Kader","year":"2000","journal-title":"Clin Radiol"},{"key":"B28","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1007\/s00586-013-3030-z","article-title":"Compensatory mechanisms contributing to keep the sagittal balance of the spine","volume":"22","author":"Barrey","year":"2013","journal-title":"Eur Spine J"},{"key":"B29","doi-asserted-by":"publisher","first-page":"2394","DOI":"10.3174\/ajnr.A4498","article-title":"MRI findings of disc degeneration are more prevalent in adults with low back pain than in asymptomatic controls: a systematic review and meta-analysis","volume":"36","author":"Brinjikji","year":"2015","journal-title":"Am J Neuroradiol"},{"key":"B30","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1097\/00007632-200006010-00009","article-title":"The rates of false-positive lumbar discography in select patients without low back symptoms","volume":"25","author":"Carragee","year":"2000","journal-title":"Spine"},{"key":"B31","doi-asserted-by":"publisher","first-page":"903","DOI":"10.1038\/sj.ijo.0802974","article-title":"Disc degeneration of the lumbar spine in relation to overweight","volume":"29","author":"Liuke","year":"2005","journal-title":"Int J Obes"},{"key":"B32","doi-asserted-by":"publisher","first-page":"990708","DOI":"10.3389\/fpubh.2022.990708","article-title":"Research progress and hotspot of the artificial intelligence application in the ultrasound during 2011-2021: a bibliometric analysis","volume":"10","author":"Xia","year":"2022","journal-title":"Front Public Health."},{"key":"B33","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.joca.2015.03.028","article-title":"Mechanics and biology in intervertebral disc degeneration: a vicious circle","volume":"23","author":"Vergroesen","year":"2015","journal-title":"Osteoarthritis Cartilage."},{"key":"B34","doi-asserted-by":"publisher","first-page":"e0178406","DOI":"10.1371\/journal.pone.0178406","article-title":"Correlation study between facet joint cartilage and intervertebral discs in early lumbar vertebral degeneration using T2, T2* and T1\u03c1 mapping","volume":"12","author":"Zhang","year":"2017","journal-title":"PLoS ONE."},{"key":"B35","doi-asserted-by":"publisher","first-page":"e1066","DOI":"10.1002\/jsp2.1066","article-title":"Imaging diagnosis for intervertebral disc","volume":"3","author":"Ogon","year":"2020","journal-title":"JOR Spine."},{"key":"B36","doi-asserted-by":"publisher","first-page":"E430","DOI":"10.1097\/BRS.0000000000001283","article-title":"Evaluation of water retention in lumbar intervertebral disks before and after exercise stress with T2 mapping","volume":"41","author":"Chokan","year":"2016","journal-title":"Spine (Phila Pa 1976)"},{"key":"B37","doi-asserted-by":"publisher","first-page":"1369","DOI":"10.3174\/ajnr.A5657","article-title":"A qualitative and quantitative correlation study of lumbar intervertebral disc degeneration using glycosaminoglycan chemical exchange saturation transfer, pfirrmann grade, and T1-?","volume":"39","author":"Togao","year":"2018","journal-title":"AJNR Am J Neuroradiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1302\/0301-620X.98B3.36036","article-title":"Diffusion tensor imaging of radiculopathy in patients with lumbar disc herniation: preliminary results","volume":"98","author":"Eguchi","year":"2016","journal-title":"Bone Joint J."},{"key":"B39","doi-asserted-by":"publisher","first-page":"6610988","DOI":"10.1155\/2021\/6610988","article-title":"Application of magnetic resonance diffusion tensor imaging in the clinical diagnosis of disc herniation after lumbar spine injury","volume":"2021","author":"Wu","year":"2021","journal-title":"J Healthc Eng."},{"key":"B40","doi-asserted-by":"publisher","first-page":"1140870","DOI":"10.3389\/fphys.2023.1140870","article-title":"Quantitative evaluation of the spinal cord compression in patients with cervical spondylotic myelopathy using synthetic MRI","volume":"14","author":"Liu","year":"2023","journal-title":"Front Physiol."}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2024.1360091\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T04:57:15Z","timestamp":1713329835000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2024.1360091\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,17]]},"references-count":40,"alternative-id":["10.3389\/fneur.2024.1360091"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2024.1360091","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,17]]},"article-number":"1360091"}}