{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T03:48:20Z","timestamp":1794023300605,"version":"4.8.0"},"reference-count":97,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T00:00:00Z","timestamp":1721692800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>The morbidity and mortality of acute ischemic hypoxic encephalopathy in newborns have not been dramatically modified over the last 20 years. The purpose of this review is to describe the use of hyperbaric oxygenation therapy (HBOT) in the management of acute ischemic hypoxic encephalopathy in newborns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A review of the medical literature was conducted on the use of HBOT in the pathophysiology of this condition and its impact on outcomes of patients treated at an early stage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>When HBOT is administered promptly, it can promote the survival of the penumbra, modulate the cytokine storm, modify inflammatory cascades, restore mitochondrial function, inhibit apoptosis, reinstate cellular communication and cytoskeleton function, reinstall the functioning of the kinase system, reduce cytotoxic and tissue edema, promote microcirculation, and provide an antioxidant effect. All these secondary mechanisms aid in saving, rescuing, and protecting the marginal tissue.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>When used promptly, HBOT is a non-invasive adjunct treatment that can preserve the marginal tissue affected by ischemia, hypoxia, meet the metabolic needs of the penumbra, reduce inflammatory cascades, prevent the extension of the damaged tissue, and modulate ischemia-reperfusion injury.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2024.1389703","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T04:50:37Z","timestamp":1721710237000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":19,"title":["Hypoxic ischemic encephalopathy (HIE)"],"prefix":"10.3389","volume":"15","author":[{"given":"E. Cuauht\u00e9moc","family":"S\u00e1nchez-Rodr\u00edguez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasthi J.","family":"L\u00f3pez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,7,23]]},"reference":[{"key":"B1","unstructured":"Stroke, Cerebrovascular Accident2023"},{"key":"B2","doi-asserted-by":"publisher","first-page":"e93","DOI":"10.1161\/CIR.0000000000001123","article-title":"Heart disease and stroke statistics-2023 update: a report from the American Heart Association","volume":"147","author":"Tsao","year":"2023","journal-title":"Circulation."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1472-4669.2009.00188.x","article-title":"Oxygen, animals, and oceanic ventilation: an alternative view","volume":"7","author":"Butterfield","year":"2009","journal-title":"Geobiology."},{"key":"B4","unstructured":"2023"},{"key":"B5","doi-asserted-by":"publisher","first-page":"2170","DOI":"10.1073\/pnas.061514798","article-title":"The references of atmospheric oxygen on earth: the innovation of oxygenic photosynthesis","volume":"98","author":"Dismukes","year":"2001","journal-title":"PNAS."},{"key":"B6","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1126\/science.119.3097.623","article-title":"Oxygen poisoning and X-irradiation: a mechanism in common","volume":"119","author":"Gerschman","year":"1954","journal-title":"Science."},{"key":"B7","doi-asserted-by":"publisher","first-page":"813","DOI":"10.3389\/fnins.2018.00813","article-title":"Hypoxia inducible factor as a central regulator of metabolism \u2013 Implications for the development of obesity","volume":"12","author":"Gaspar","year":"2018","journal-title":"Front Neurosci."},{"key":"B8","doi-asserted-by":"publisher","first-page":"728","DOI":"10.4103\/0028-3886.263236","article-title":"Hyperbaric oxygen therapy in patients with hypoxic ischemic encephalopathy","volume":"67","author":"Sankaran","year":"2019","journal-title":"Neurol India."},{"key":"B9","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3892\/mmr.2021.12557","article-title":"HIF-1\u03b1 in cerebral ischemia (review)","volume":"25","author":"Dong","year":"2022","journal-title":"Mol Med Rep."},{"key":"B10","doi-asserted-by":"publisher","first-page":"26","DOI":"10.55730\/1300-0144.5762","article-title":"The otential mechanism of treating IC\/BPS with hyperbaric oxygen by reducing vascular endothelial growth inhibitor and hypoxic-inducible factor-1\u03b1","volume":"54","author":"Zhang","year":"2024","journal-title":"Turkish J Med Science."},{"key":"B11","doi-asserted-by":"publisher","first-page":"2856","DOI":"10.7150\/thno.88223","article-title":"Activation of hypoxia-inducible factor pathway protects against acute ischemic stroke by reprogramming central carbon metabolism","volume":"14","author":"Madai","year":"2024","journal-title":"Theranostics."},{"key":"B12","doi-asserted-by":"publisher","first-page":"105605","DOI":"10.1016\/j.neuint.2023.105605","article-title":"HIF-1, an important regulator in potential new therapeutic approaches to ischemic stroke","volume":"17","author":"Vatte","year":"2023","journal-title":"Neurochem Int."},{"key":"B13","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.3892\/mmr.2017.6277","article-title":"Role of hypoxia-inducible factor-1\u03b1 in autophagic cell death in microglial cells induced by hypoxia","volume":"15","author":"Wang","year":"2017","journal-title":"Molec Med Rep."},{"key":"B14","doi-asserted-by":"publisher","first-page":"39728","DOI":"10.1074\/jbc.M204619200","article-title":"Genomic response following hypoxia and reoxygenation in neonatal rat","volume":"277","author":"Bernaudin","year":"2002","journal-title":"J Biolog Chem."},{"key":"B15","doi-asserted-by":"publisher","first-page":"2964","DOI":"10.1002\/jnr.24943","article-title":"Neuronal deficiency of hypoxia-inducible fator-2\u03b1 increases hypoxic-ischemic brain injury in neonatal mice","volume":"99","author":"Sun","year":"2021","journal-title":"J Neurosci Res."},{"key":"B16","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1007\/s10456-021-09796-4","article-title":"Hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome","volume":"24","author":"Tsao","year":"2021","journal-title":"Angiogenesis."},{"key":"B17","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1155\/2021\/9928232","article-title":"Role of NADPH oxidase-induced hypoxia-induced factor 1\u03b1 increase in blood brain barrier disruption after 2 -hour focal ischemic stroke in rat","volume":"9928322","author":"Wang","year":"2017","journal-title":"Neural Plasticity"},{"key":"B18","doi-asserted-by":"publisher","first-page":"707136","DOI":"10.3389\/fped.2022.707136","article-title":"Efficacy and prognosis on hyperbaric oxygen as adjuvant therapy for neonatal hypoxic-ischemic encephalopathy: a meta-analysis study","volume":"10","author":"Gong","year":"2022","journal-title":"Front Pediatr."},{"key":"B19","doi-asserted-by":"publisher","first-page":"e148","DOI":"10.1542\/neo.22-3-e148","article-title":"Neonatal encephalopathy: beyond hypoxic-ischemic encephalopathy","volume":"22","author":"Russ","year":"2021","journal-title":"Neoreviews."},{"key":"B20","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/j.mito.2020.11.010","article-title":"Severe life stress, mitochondrial dysfunction, and depressive behavior: a pathophysiological and therapeutic perspective","volume":"56","author":"Allen","year":"2021","journal-title":"Mitochondrion."},{"key":"B21","doi-asserted-by":"publisher","first-page":"105951","DOI":"10.1016\/j.psyneuen.2022.105951","article-title":"The energetic cost of allostasis and allostatic load","volume":"146","author":"Boba-Alves","year":"2022","journal-title":"Phsychoneuroendocrinol."},{"key":"B22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.21037\/jeccm.2019.04.03","article-title":"Pathophysiology of ischemia-reperfusion injury and its management with hyperbaric oxygen (HBO): a review","volume":"3","author":"Sanchez","year":"2019","journal-title":"J Emerg Crit Care Med."},{"key":"B23","doi-asserted-by":"publisher","first-page":"1122","DOI":"10.1016\/j.freeradbiomed.2015.07.156","article-title":"Preparation for oxidative stress under hypoxia and metabolic depression: revisiting the proposal two decades later","volume":"89","author":"Hermes-Lima","year":"2015","journal-title":"Free Rad Biol Med."},{"key":"B24","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1038\/s41586-020-2551-y","article-title":"Na+ controls hypoxic signaling by the mitochondrial respiratory chain","volume":"586","author":"Hernansanz-Agustin","year":"2020","journal-title":"Nature."},{"key":"B25","doi-asserted-by":"publisher","first-page":"eadd6364","DOI":"10.1126\/scisignal.add6364","article-title":"Cation influx through SUR1-TRPM4 and NCX1 in astrocyte end feet induces water influx through AQP4 and brain swelling after ischemic stroke","volume":"16","author":"Stokum","year":"2021","journal-title":"Sci Signal."},{"key":"B26","first-page":"1049","article-title":"Management of acute ischemic hypoxic encephalopathy in newborns with hyperbaric oxygen: a review","volume":"3","author":"Sanchez","year":"2016","journal-title":"Austin J Cerebrovasc Dis Stroke."},{"key":"B27","doi-asserted-by":"publisher","first-page":"7420","DOI":"10.3390\/ijms23137420","article-title":"Ferroptosis: a promising therapeutic target for neonatal hypoxic-ischemic brain injury","volume":"23","author":"Peeples","year":"2022","journal-title":"Int J Mol Sci."},{"key":"B28","doi-asserted-by":"publisher","first-page":"2661","DOI":"10.2147\/JIR.S414316","article-title":"The emerging roles of ferroptosis in neonatal diseases","volume":"16","author":"Chen","year":"2023","journal-title":"J Inflamm Res."},{"key":"B29","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1089\/ars.2020.8093","article-title":"Hypoxic-ischemic encephalopathy and mitochondrial dysfunction: facts, unknowns, and challenges","volume":"33","author":"Rodr\u00edguez","year":"2020","journal-title":"Antioxid Redox Signal."},{"key":"B30","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s11658-023-00423-2","article-title":"Endothelial dysfunction due eNOS uncoupling molecular mechanisms as therapeutic targets","volume":"28","author":"Janaszak-Jaslecka","year":"2023","journal-title":"Cell Molec Biol."},{"key":"B31","doi-asserted-by":"publisher","first-page":"100370","DOI":"10.1016\/j.bbih.2021.100370","article-title":"CCL4 induces inflammatory signaling and barrier disruption of neurovascular endothelium","volume":"18","author":"Estevao","year":"2021","journal-title":"Brain Behav Immun Health."},{"key":"B32","doi-asserted-by":"publisher","first-page":"024115","DOI":"10.1063\/1.5143391","article-title":"The effect of shear stress reduction on endothelial cells: a microfluidic study of actin skeleton","volume":"14","author":"Inglebert","year":"2020","journal-title":"Biomicrofluids."},{"key":"B33","doi-asserted-by":"publisher","first-page":"146297","DOI":"10.1016\/j.brainres.2019.06.016","article-title":"The temporal spatial changes of actin cytoskeleton in the hippocampal CA1 neurons following transient cerebral ischemia","volume":"1720","author":"Guo","year":"2019","journal-title":"Brain Res."},{"key":"B34","doi-asserted-by":"publisher","first-page":"E3882","DOI":"10.1073\/pnas.1618007114","article-title":"Geometry dictates TNF\u03b1-induced genome response","volume":"114","author":"Mitra","year":"2017","journal-title":"PNAS."},{"key":"B35","doi-asserted-by":"publisher","first-page":"824","DOI":"10.2174\/1574888X16666210712100002","article-title":"Hippo signaling: a stress response pathway in stem cells","volume":"16","author":"Zeybek","year":"2021","journal-title":"Curr Stem Cell Res Ther."},{"key":"B36","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.tcb.2019.10.005","article-title":"The Hippo Pathway, YAP\/TAZ, and the plasma membranes","volume":"30","author":"Rausch","year":"2019","journal-title":"Trends Cell Biol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"9765","DOI":"10.3390\/ijms22189765","article-title":"AMPK-mTOR signaling and cellular adaptations in hypoxia","volume":"22","author":"Chun","year":"2021","journal-title":"Int J Mol Sci."},{"key":"B38","doi-asserted-by":"publisher","first-page":"3803","DOI":"10.1038\/s41467-023-39514-1","article-title":"An optogenetic-phosphoproteomic study reveals dynamic AKT1 signaling profiles in endothelial cells","volume":"14","author":"Zhou","year":"2023","journal-title":"Nature Comm."},{"key":"B39","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1016\/j.trsl.2018.07.014","article-title":"Mitochondria in innate immune signaling","volume":"202","author":"Banoth","year":"2018","journal-title":"Transl Res."},{"key":"B40","doi-asserted-by":"publisher","first-page":"9335166","DOI":"10.1155\/2023\/9335166","article-title":"TLR4 enhances cerebral ischemia\/reperfusion injury via regulating NLRP3 inflammasome and autophagy","volume":"2023","author":"Mao","year":"2023","journal-title":"Mediator Inflamm."},{"key":"B41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1113\/JP284588","article-title":"Neuroinflammation and the immune system in hypoxic ischemic brain injury pathophysiology after cardiac arrest","volume":"2023","author":"Sekhon","year":"2023","journal-title":"J Physiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1002\/ana.410090206","article-title":"The influence of immaturity on hypoxic ischemic brain damage in the rat","volume":"9","author":"Rice","year":"1981","journal-title":"Ann Neurol."},{"key":"B43","first-page":"1752","article-title":"Hyperbaric oxygenation promotes neural stem cell proliferation and protects the learning and memory ability in neonatal hypoxic-ischemic brain damage","volume":"8","author":"Wei","year":"2015","journal-title":"Int J Clin Exp Pathol."},{"key":"B44","doi-asserted-by":"publisher","first-page":"137015","DOI":"10.1016\/j.neulet.2022.137015","article-title":"Effect of hyperbaric oxygen on myelin injury and repair after hypoxic-ischemic brain damage in adult rat","volume":"794","author":"Xue","year":"2023","journal-title":"Neurosci Lett."},{"key":"B45","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.brainres.2008.05.016","article-title":"Therapeutic window of hyperbaric therapy in hypoxic-ischemic brain damage in newborn rats","volume":"1222","author":"Wang","year":"2008","journal-title":"Brain Res."},{"key":"B46","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.neulet.2009.09.011","article-title":"Effect of combined therapy with epinephrine and hyperbaric oxygen in hypoxic-ischemic brain injury","volume":"465","author":"Chen","year":"2009","journal-title":"Neurosc Letters."},{"key":"B47","doi-asserted-by":"publisher","first-page":"136","DOI":"10.3892\/br.2016.673","article-title":"Effect of hyperbaric oxygen on lipid peroxidation and development in neonatal rats with hypoxia-ischemia brain damage","volume":"5","author":"Chen","year":"2016","journal-title":"Biomed Rep."},{"key":"B48","first-page":"66","article-title":"Effect of hyperbaric oxygen on neurological recovery of neonatal rats following hypoxic-ischemic brain damage and its underlying mechanism","volume":"6","author":"Yin","year":"2013","journal-title":"Int J Clin Pathol"},{"key":"B49","doi-asserted-by":"publisher","first-page":"1220","DOI":"10.4103\/1673-5374.112859","article-title":"Hyperbaric oxygen treatment promotes neural stem cell proliferation in the subventricular zone of neonatal rats with hypoxic-ischemic brain damage","volume":"8","author":"Feng","year":"2013","journal-title":"Neural Reg Res."},{"key":"B50","doi-asserted-by":"publisher","first-page":"1753","DOI":"10.1097\/WNR.0b013e3282f0ec09","article-title":"Proliferation of neural stem cells correlates with Wnt-3 protein in hypoxic-ischemic neonate rats after hyperbaric oxygen therapy","volume":"18","author":"Wang","year":"2007","journal-title":"NeuroRep."},{"key":"B51","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1590\/s0102-865020170040000002","article-title":"Effects of hyperbaric oxygen on nerve growth factor on the long-term neural behaivor of neonatal rats with hypoxic-ischemic brain damage","volume":"32","author":"Wei","year":"2017","journal-title":"Acta Cir Bras."},{"key":"B52","doi-asserted-by":"publisher","first-page":"e5187","DOI":"10.1590\/1414-431x20165187","article-title":"Hyperbaric oxygenation on mitochondrial function of neuronal cells in the cortex of neonatal rats after hypoxic-ischemic brain damage","volume":"49","author":"Yang","year":"2016","journal-title":"Br J Med Biolog Res."},{"key":"B53","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.brainres.2007.12.039","article-title":"Mechanism of hyperbaric oxygen preconditioning in neonatal hypoxia-ischemia rat model","volume":"1196","author":"Li","year":"2008","journal-title":"Brain Res."},{"key":"B54","doi-asserted-by":"publisher","first-page":"2072","DOI":"10.1152\/japplphysiol.00630.2003","article-title":"Effect of hyperbaric oxygenation on apoptosis in neonatal hypoxia-ischemia rat model","volume":"95","author":"Calvert","year":"2003","journal-title":"J Appl Physiol."},{"key":"B55","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1177\/0963689719883578","article-title":"HBO promotes the differentiation of neural stem cells via interactions between the Wnt3\/b-catenin and BMP2 Signaling pathways","volume":"28","author":"Chen","year":"2019","journal-title":"Cell Transplant."},{"key":"B56","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1097\/01.PCC.0000257113.75488.84","article-title":"Oxygen treatment restores energy status following experimental neonatal hypoxia-ischemia","volume":"8","author":"Calvert","year":"2007","journal-title":"Pediatr Crit Care Med."},{"key":"B57","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.expneurol.2004.05.030","article-title":"Transient exposure of rat pups to hyperoxia at normobaric and hyperbaric pressure does not cause retinopathy of prematurity","volume":"189","author":"Calvert","year":"2004","journal-title":"Exper Neurol."},{"key":"B58","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1152\/japplphysiol.00268.2006","article-title":"Oxygen treatment after experimental hypoxia-ischemia in neonatal rat alters the expression of HIF-1 and its downstream target genes","volume":"101","author":"Calvert","year":"2006","journal-title":"J Appl Physiol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1016\/j.neuint.2004.06.013","article-title":"Hyperbaric and normobaric reoxygenation of hypoxic rat brain slices \u2013 impact of purine nucleotides and cell viability","volume":"45","author":"G\u00fcnther","year":"2004","journal-title":"Neurochem Int."},{"key":"B60","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1016\/j.neuint.2013.03.004","article-title":"Hyperbaric oxygenation reduces long term brain injury and ameliorates behavioral function by suppression of apoptosis in a rat model of neonatal hypoxia-ischemia","volume":"62","author":"Liu","year":"2013","journal-title":"Neurochem Int."},{"key":"B61","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0006-8993(02)03094-9","article-title":"Hyperbaric oxygenation prevented brain injury induced by hypoxia-ischemia in a neonatal rat model","volume":"951","author":"Calvert","year":"2002","journal-title":"Brain Res."},{"key":"B62","doi-asserted-by":"publisher","first-page":"24","DOI":"10.28920\/dhm47.2.131-132","article-title":"10th European Consensus Conference on hyperbaric medicine","volume":"47","author":"Mathieu","year":"2017","journal-title":"Diving Hyperb Med."},{"key":"B63","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1016\/0140-6736(90)90777-3","article-title":"Enhancing \u201cidling\u201d neurons","volume":"335","author":"Neubauer","year":"1990","journal-title":"Lancet."},{"key":"B64","volume-title":"Hyperbaric Oxygen Therapy Indications, 15th Edition.","author":"Huang","year":"2023"},{"key":"B65","doi-asserted-by":"publisher","first-page":"1559325820970821","DOI":"10.1177\/1559325820970821","article-title":"Expression of aquaporin-1 and Aquaporin-5 in a rat model of high-altitude pulmonary edema and the effect of hyperbaric oxygen exposure","volume":"18","author":"Tan","year":"2020","journal-title":"Dose Response."},{"key":"B66","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.3390\/biom10091247","article-title":"Molecular and therapeutic aspects of hyperbaric oxygen therapy in neurological conditions","volume":"10","author":"Fisher","year":"2020","journal-title":"Biomolecules."},{"key":"B67","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1111\/cns.13124","article-title":"Prophylactic treatment of hyperbaric oxygen treatment mitigates inflammatory response via mitochondrial transfer","volume":"25","author":"Lippert","year":"2019","journal-title":"CNS Neurosci Ther."},{"key":"B68","doi-asserted-by":"publisher","first-page":"1827","DOI":"10.3390\/biom11121827","article-title":"Hyperbaric oxygen treatment: Effect on mitochondrial function and oxidative stress","volume":"11","author":"Schottlender","year":"2021","journal-title":"Biomolecules."},{"key":"B69","doi-asserted-by":"publisher","first-page":"117170","DOI":"10.1016\/j.lfs.2019.117170","article-title":"Hyperbaric oxygen alleviated cognitive impairments in mice induced by repeated cerebral ischemia-reperfusion injury via inhibition of autophagy","volume":"241","author":"Chen","year":"2020","journal-title":"Life Sci."},{"key":"B70","doi-asserted-by":"publisher","first-page":"e0237746","DOI":"10.1371\/journal.pone.0237746","article-title":"Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic-non-healing wound","volume":"15","author":"Baiula","year":"2020","journal-title":"PLoS ONE."},{"key":"B71","doi-asserted-by":"publisher","first-page":"e00959","DOI":"10.1002\/brb3.959","article-title":"An overview of protective strategies against ischemia\/reperfusion injury: the role of hyperbaric oxygen preconditioning","volume":"8","author":"Hentia","year":"2018","journal-title":"Brain Behav."},{"key":"B72","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.3390\/biom11081210","article-title":"The effect of hyperbaric oxygenation on oxidative stress, inflammation, and angiogenesis","volume":"11","author":"De Wolde","year":"2021","journal-title":"Biomolecules."},{"key":"B73","doi-asserted-by":"publisher","first-page":"147097","DOI":"10.1016\/j.brainres.2020.147097","article-title":"Effect of repetitive hyperbaric oxygen therapy on neuroprotection of middle cerebral artery occlusion rats","volume":"1748","author":"Chang","year":"2020","journal-title":"Brain Res."},{"key":"B74","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1097\/WNR.0000000000001719","article-title":"Hyperbaric oxygen therapy improves neurological function via p38-MAPK\/CCL2 signaling pathway following traumatic brain injury","volume":"32","author":"Jiang","year":"2021","journal-title":"Neuroreport."},{"key":"B75","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1097\/CNQ.0b013e318294e9e3","article-title":"Mechanisms of action of hyperbaric oxygenation in stroke","volume":"36","author":"Sanchez","year":"2013","journal-title":"Crit Care Nurs Q."},{"key":"B76","doi-asserted-by":"publisher","first-page":"101","DOI":"10.4103\/bc.bc_31_19","article-title":"Hyperbaric oxygen therapy: a new a new look for treating stroke and traumatic brain injury","volume":"30","author":"Gonzales-Portillo","year":"2019","journal-title":"Brain Circ."},{"key":"B77","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1186\/s12883-024-03555-w","article-title":"Efficacy and safety of hyperbaric oxygen therapy in acute ischemic stroke; a systematic review and meta-analysis","volume":"3","author":"Li","year":"2024","journal-title":"BMC Neurol."},{"key":"B78","doi-asserted-by":"publisher","first-page":"1677","DOI":"10.1002\/jcp.29955","article-title":"The effects of hyperbaric oxygen therapy on the brain with middle cerebal artery occlusion","volume":"236","author":"Thiankhaw","year":"2021","journal-title":"J Cell Physiol."},{"key":"B79","doi-asserted-by":"publisher","first-page":"93","DOI":"10.3233\/RNN-190959","article-title":"Hyperbaric oxygen therapy improves neurocognitive functions of post-stroke patients \u2013 a retrospective analysis","volume":"38","author":"Hadanny","year":"2020","journal-title":"Rest Neurol Neurosci."},{"key":"B80","first-page":"265","article-title":"Results of acute cerebral infarction treatment with hyperbaric oxygen therapy, 2020-2022","volume":"74","author":"Nguyen","year":"2023","journal-title":"Int Marit Health."},{"key":"B81","doi-asserted-by":"publisher","first-page":"P1334","DOI":"10.1016\/S0140-6736(63)90881-X","article-title":"Hyperbaric oxygen in resuscitation of the newborn","volume":"282","author":"Hutchinson","year":"1963","journal-title":"Lancet."},{"key":"B82","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1097\/00006254-196508000-00010","article-title":"Treatment of asphyxia neonatorum by hyperbaric oxygenation","volume":"20","author":"Hutchinson","year":"1965","journal-title":"Obst Gynecol Surv."},{"key":"B83","first-page":"202","article-title":"The use of hyperbaric oxygenation in neonates with intracranial birth trauma","author":"Pilinoga","year":"1981","journal-title":"Proceedings of VIIth International Congress on Hyperbaric Medicine"},{"key":"B84","first-page":"295","article-title":"The use of HBO to treat hemolytic diseases in neonates","author":"Kiselev","year":"1981"},{"key":"B85","first-page":"299","article-title":"Some features of the use of hyperbaric oxygenation to treat acute respiratory insufficiency in newborn children","author":"Bayboradov","year":"1981","journal-title":"Proceedings of VIIth International Congress on Hyperbaric Medicine"},{"key":"B86","doi-asserted-by":"publisher","first-page":"280","DOI":"10.1097\/CNQ.0b013e318294e95b","article-title":"The use of hyperbaric oxygenation in neonatal patients: a pilot study of 8 cases","volume":"36","author":"Sanchez","year":"2013","journal-title":"Crit Care Nurs Q."},{"key":"B87","first-page":"218","article-title":"Hyperbaric oxygen in the treatment of asphyxia in two newborn infants","volume":"40","author":"Orozco-Gutierrez","year":"2010","journal-title":"Diving Hyperb Med."},{"key":"B88","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1136\/bmj.38776.731655.2F","article-title":"Clinical effectiveness of treatment with hyperbaric oxygen for neonatal hypoxic-ischemic encephalopathy: systematic review of Chinese literature","volume":"333","author":"Liu","year":"2006","journal-title":"BMJ."},{"key":"B89","article-title":"Efficacy of hyperbaric oxygen therapy under different pressures on neonatal hypoxic-ischemic encephalopathy","author":"Zhou","year":"2008","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi."},{"key":"B90","first-page":"3833","article-title":"Monosialotethrasylganglioside sodium combined with hyperbaric oxygen on nervous system development and brain physiology in children with hypoxic ischemic encephalopathy","volume":"13","author":"Wang","year":"2021","journal-title":"Am J Transl Res."},{"key":"B91","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1542\/peds.82.2.193","article-title":"Oxygen-induced retinopathy in newborn rats: effects of prolonged normobaric and hyperbaric oxygen supplementation","volume":"82","author":"Ricci","year":"1998","journal-title":"Pediatrics."},{"key":"B92","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/S0014-4835(89)80039-9","article-title":"Variations in the severity of retinopathy seen in newborn rats supplemented with oxygen under different conditions of hyperbarism","volume":"49","author":"Ricci","year":"1989","journal-title":"Exp Eye Res."},{"key":"B93","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1007\/BF00183596","article-title":"Oxygen-induced retinopathy in the newborn rat: effect of hyperbarism and topical administration of timodol maleate","volume":"233","author":"Ricci","year":"1995","journal-title":"Graefes Arch Clin Exp Opthalmol."},{"key":"B94","doi-asserted-by":"publisher","first-page":"CD003311","DOI":"10.1002\/14651858.CD003311.pub3","article-title":"Cooling of newborns with hypoxic ischemic encephalopathy","volume":"2013","author":"Jacobs","year":"2013","journal-title":"Cochrane Database Syst Rev."},{"key":"B95","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1007\/s11910-019-0916-0","article-title":"Therapeutic hypothermia in neonatal hypoxic-ischemic encephalopathy","volume":"19","author":"Wassink","year":"2019","journal-title":"Curr Neurol Rep."},{"key":"B96","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1007\/s00431-021-04320-8","article-title":"New possibilities for neuroprotection in neonatal hypoxic-ischemic encephalopathy","volume":"181","author":"Victor","year":"2022","journal-title":"Eur J Pediatr."},{"key":"B97","doi-asserted-by":"publisher","first-page":"86","DOI":"10.7499\/j.issn.1008-8830.2209122","article-title":"A neonatal intelligent regulation system based on the combination of mild hypothermia mattress and hyperbaric oxygen chamber: introduction to a patent","volume":"25","author":"Zhu","year":"2023","journal-title":"Zhongguo Dang Dai Er Ke Za Zhi."}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2024.1389703\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T04:50:45Z","timestamp":1721710245000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2024.1389703\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,23]]},"references-count":97,"alternative-id":["10.3389\/fneur.2024.1389703"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2024.1389703","relation":{},"ISSN":["1664-2295"],"issn-type":[{"value":"1664-2295","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,23]]},"article-number":"1389703"}}