{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:30:07Z","timestamp":1791772207446,"version":"4.3.4"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>This study aimed to investigate the impact of early vestibular rehabilitation training combined with corticosteroids initiated within 2\u2009weeks, compared with corticosteroid treatment, after the peripheral acute vestibular syndrome (pAVS) onset.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Data sources<\/jats:title>\n                    <jats:p>PubMed, CINAHL, EMBASE, and SCOPUS. From inception to January 24, 2024. The International Prospective Register of Systematic Reviews approved this study (CRD42023422308).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Five studies involving 235 patients were included in this systematic review and meta-analysis. The subjective outcome measure Dizziness Handicap Inventory (DHI) was pooled for a meta-analysis and was statistically significantly in favor of early vestibular rehabilitation training (early VRT) plus corticosteroids compared with corticosteroids alone: at one-month follow-up (\n                      <jats:italic>p<\/jats:italic>\n                      =\u20090.00) and 12\u2009months follow-up (\n                      <jats:italic>p<\/jats:italic>\n                      =\u20090.01). DHI was a critical outcome for measuring the differences in effect of early VRT. The objective outcome measures of caloric lateralization, cervical vestibular-evoked myogenic potentials, and posturography were gathered for a narrative synthesis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This meta-analysis showed that early VRT in combination with corticosteroids was more effective for treating pAVS than corticosteroid treatment alone. No adverse effects were reported for early VRT.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2024.1396891","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T07:28:46Z","timestamp":1717054126000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":10,"title":["Early vestibular rehabilitation training of peripheral acute vestibular syndrome\u2014a systematic review and meta-analysis"],"prefix":"10.3389","volume":"15","author":[{"given":"Helle Elisabeth","family":"Agger-Nielsen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas Stig","family":"Gr\u00f8ndberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Berg-Beckhoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Therese","family":"Ovesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1056\/NEJM199809033391007","article-title":"Acute vestibular syndrome","volume":"339","author":"Hotson","year":"1998","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"788","DOI":"10.1161\/STROKEAHA.117.016979","article-title":"Diagnosing stroke in acute dizziness and vertigo: pitfalls and pearls","volume":"49","author":"Saber Tehrani","year":"2018","journal-title":"Stroke"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3238\/arztebl.2011.0197","article-title":"Central oculomotor disturbances and nystagmus: a window into the brainstem and cerebellum","volume":"108","author":"Strupp","year":"2011","journal-title":"Dtsch Arztebl Int"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1136\/svn-2018-000160","article-title":"Use of HINTS in the acute vestibular syndrome. 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