{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:46:52Z","timestamp":1792176412937,"version":"4.4.0"},"reference-count":28,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>This study aims to compare the efficacy and long-term prognosis of microvascular decompression (MVD) versus percutaneous balloon compression (PBC) in patients with idiopathic V2 (maxillary branch) trigeminal neuralgia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed the clinical information and follow-up data of patients who underwent surgical treatment for V2 idiopathic trigeminal neuralgia from January 2020 to January 2023. A total of 58 patients were included in the MVD group and 99 in the PBC group. All surgeries were performed by two physicians at the same center, with follow-up conducted by a separate, trained researcher. We compared the initial versus 12-month postoperative pain relief rates (scored using the BNI), surgical complications, and described pain relief rates after long-term follow-up in both groups using Kaplan\u2013Meier analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study included a total of 157 patients (MVD 58, PBC 99). The median age of patients in the MVD group was lower than that in the PBC group (58 [51\u201365] vs. 63 [58\u201369], <jats:italic>p<\/jats:italic>\u2009=\u20090.002). There was no significant difference between the two groups in terms of pain relief rates initially after surgery and at 12\u2009months (<jats:italic>p<\/jats:italic>\u2009=\u20090.521, <jats:italic>p<\/jats:italic>\u2009=\u20090.713). However, the MVD group had significantly better outcomes regarding postoperative facial numbness (<jats:italic>p<\/jats:italic>\u2009&amp;lt;\u20090.0001), masticatory weakness (<jats:italic>p<\/jats:italic>\u2009=\u20090.0017), and other complications (<jats:italic>p<\/jats:italic>\u2009=\u20090.04). Kaplan\u2013Meier analysis showed that MVD provided a longer duration of pain relief than PBC (<jats:italic>p<\/jats:italic>\u2009=\u20090.0323), with most recurrences in both groups occurring within 1\u20132\u2009years after surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>There were no significant differences in significant pain relief rates between the two groups initially after surgery and at 12\u2009months. However, the MVD group showed a clear advantage over PBC regarding postoperative facial numbness, masticatory weakness, and other complications; moreover, Kaplan\u2013Meier analysis revealed that MVD offers a longer duration of pain relief for patients.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2024.1406602","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T04:47:27Z","timestamp":1728967647000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Comparison of microvascular decompression and percutaneous balloon compression efficacy in patients with V2 idiopathic trigeminal neuralgia"],"prefix":"10.3389","volume":"15","author":[{"given":"Ye","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junwu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1111\/ene.13950","article-title":"European academy of neurology guideline on trigeminal neuralgia","volume":"26","author":"Bendtsen","year":"2019","journal-title":"Eur J Neurol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1464","DOI":"10.1016\/j.pain.2014.04.020","article-title":"Magnetic resonance imaging contribution for diagnosing symptomatic neurovascular contact in classical trigeminal neuralgia: a blinded case-control study and meta-analysis","volume":"155","author":"Antonini","year":"2014","journal-title":"Pain"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1093\/brain\/awu349","article-title":"Significance of neurovascular contact in classical trigeminal neuralgia","volume":"138","author":"Maarbjerg","year":"2015","journal-title":"Brain"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"411","DOI":"10.3171\/2019.3.JNS183174","article-title":"Significance of degree of neurovascular compression in surgery for trigeminal neuralgia","volume":"133","author":"Hughes","year":"2019","journal-title":"J Neurosurg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1097\/j.pain.0000000000001365","article-title":"The IASP classification of chronic pain for ICD-11: chronic neuropathic pain","volume":"160","author":"Scholz","year":"2019","journal-title":"Pain"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/0333102417738202","article-title":"Anonymou. 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