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Additionally, the interaction between the BDNF Val66Met genetic polymorphism and exercise on cognitive function is examined. The review emphasizes the possibility of exercise as a complementary therapy for neurodegenerative diseases, although further research is required to fully understand its effects.<\/jats:p>","DOI":"10.3389\/fneur.2024.1505879","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T05:10:58Z","timestamp":1738041058000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":64,"title":["Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases"],"prefix":"10.3389","volume":"15","author":[{"given":"Ana","family":"Romero Garavito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valery","family":"D\u00edaz Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estherz","family":"Ju\u00e1rez 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