{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T17:43:55Z","timestamp":1767203035990,"version":"build-2238731810"},"reference-count":33,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To explore the characteristics of resting-state functional connectivity in patients with different outcomes of prolonged disorders of consciousness (pDoC) by studying resting-state near-infrared imaging in patients with pDoC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>60 patients with pDoC were processed with resting-state near-infrared imaging and divided into unresponsive wakefulness syndrome\/vegetative state (UWS\/VS) group, minimally conscious state (MCS) group and escape minimally conscious state (EMCS) group according to the post-treatment state of consciousness, to analyze the difference of resting-state functional connectivity in patients with different outcomes of patients with pDoC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Functional connectivity (FC) between frontal lobe and left occipital lobe, frontal lobe and right occipital lobe, and left and right occipital lobes decreased in the UWS\/VS group compared with the MCS group; functional connectivity between frontal lobe and left occipital lobe, frontal lobe and right occipital lobe, and left and right occipital lobes decreased in the UWS\/VS group compared with the EMCS group; functional connectivity did not show any significant difference between the EMCS and MCS groups; and functional connectivity was more centralized in the MCS group and EMCS group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Different outcomes of patients with pDoC have different degrees of decline in functional connectivity between frontal lobe and occipital lobe and between occipital lobe, resting-state functional near-infrared spectroscopy has a certain reference significance for the prognosis of patients with pDoC, and it is helpful for exploring the exploration of the conscious residual brain areas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2025.1533853","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:10:07Z","timestamp":1748823007000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["A study on resting-state functional near-infrared spectroscopy in patients with different outcomes of prolonged disorders of consciousness"],"prefix":"10.3389","volume":"16","author":[{"given":"Yanli","family":"Liang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijiang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaowen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinuo","family":"Bi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Xue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenyu","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,6,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1186\/1471-2377-9-35","article-title":"Diagnostic accuracy of the vegetative and minimally conscious state: clinical consensus versus standardized neurobehavioral assessment","volume":"9","author":"Caroline","year":"2009","journal-title":"BMC Neurol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1212\/WNL.0000000000005926","article-title":"Practice guideline update recommendations summary: disorders of consciousness: report of the guideline development, dissemination, and implementation Subcommittee of the American Academy of neurology; 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