{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T16:05:49Z","timestamp":1753891549896,"version":"3.41.2"},"reference-count":17,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Postoperative motor aphasia is a common complication following left-sided combined revascularization surgery for Moyamoya disease (MMD), yet reliable preoperative predictors remain unavailable. This study evaluates preoperative temporal muscle thickness (TMT), a novel MRI-based parameter, as a predictive biomarker for this complication.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively analyzed 34 adult MMD patients who underwent left-sided combined revascularization between April 2021 and June 2023. Preoperative TMT was measured on axial MRI using multi-planar reformation. Statistical analyses (e.g., <jats:italic>t<\/jats:italic>-tests) were used to assess the association between preoperative TMT and the incidence, timing, and duration of postoperative motor aphasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Excluding complications such as infarction, postoperative aphasia occurred in 28 of 34 patients (82.35%), predominantly pure motor aphasia (25\/34, 73.53%), typically emerging on the third postoperative day with a median duration of 4\u202fdays. Patients who developed aphasia had significantly greater mean preoperative TMT than those who did not (7.08\u202f\u00b1\u202f1.00\u202fmm vs. 5.70\u202f\u00b1\u202f0.68\u202fmm, respectively; <jats:italic>p<\/jats:italic>\u202f=\u202f0.003). Furthermore, greater preoperative TMT showed a positive correlation with a longer duration of postoperative aphasia (<jats:italic>r<\/jats:italic>\u202f=\u202f0.4907, <jats:italic>p<\/jats:italic>\u202f=\u202f0.0032).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings confirm that TMT independently predicts the occurrence and severity of postoperative motor aphasia in MMD patients after left-sided revascularization. This MRI metric enhances risk stratification, guiding surgical planning and patient counseling. Further studies are needed to validate its utility and explore preventive measures.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2025.1598387","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T15:31:06Z","timestamp":1748359866000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Temporal muscle thickness as a preoperative predictor of motor aphasia in Moyamoya 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