{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:03:32Z","timestamp":1781910212846,"version":"3.54.5"},"reference-count":27,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:00:00Z","timestamp":1758844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study explores the correlation between carotid plaques and cerebral small vessel disease (CSVD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A total of 167 patients were divided into CSVD (<jats:italic>n<\/jats:italic> = 119) and Non-CSVD (<jats:italic>n<\/jats:italic> = 48) groups. Various clinical variables, including body mass index (BMI), coronary artery disease, hypertension, and carotid plaque echo characteristics, were evaluated using multivariate logistic regression analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The analysis revealed that carotid isoechoic plaques (OR = 2.139, 95% CI 1.421\u20133.219, <jats:italic>P<\/jats:italic> &amp;lt; 0.001) and hypoechoic plaques (OR = 1.687, 95% CI 1.206\u20132.359, <jats:italic>P<\/jats:italic> = 0.002) are independent risk factors for CSVD. Other variables such as BMI, coronary artery disease, hypertension, and hyperlipidemia did not reach statistical significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The presence of carotid isoechoic and hypoechoic plaques significantly increases the risk of CSVD, highlighting the importance of carotid imaging in assessing stroke risk and guiding clinical management.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2025.1625480","type":"journal-article","created":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T05:34:47Z","timestamp":1758864887000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The correlation analysis between preoperative cerebral small vessel disease and carotid plaque echo 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