{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:41:31Z","timestamp":1789663291867,"version":"4.0.1"},"reference-count":31,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:00:00Z","timestamp":1756425600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Basilar trunk aneurysms (BTAs) are rare and challenging to treat, with a high complication rate. This study aimed to analyze and evaluate the complications and long-term outcomes associated with endovascular treatment (EVT) of BTAs and identify risk factors for post-procedural complications and unfavorable clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, observational cohort study included 90 patients (92 BTAs) treated with EVTs from January 2011 to April 2023. Factors associated with post-procedural complications and unfavorable clinical outcomes were analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      All 90 patients (92 aneurysms) were successfully treated, of which 63 (68.5%) aneurysms were small, 26 (28.3%) were large, and 3 (3.3%) were giant; 23 (25%) were saccular, and 69 (75%) were fusiform and\/or dissecting. A total of 36 (40.0%) patients were admitted with ruptured aneurysm. The median follow-up duration was 51.0 months (IQR 21.0\u20133.0). The favorable clinical outcome rate was 75.6% (68\/90). The overall complication rate was 33.33% (30\/90), with ischemic and hemorrhagic complications occurring in 25.6% (23\/90) and 2.2% (2\/90) of cases, respectively. The mortality rate was 8.9% (8\/90). Unilateral vertebral artery sacrifice (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.015), Glasgow Coma Scale (GCS) grade \u226412 before the procedure (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.047), and age \u226560 years (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.006) were associated with overall post-procedural complications. Diabetes mellitus (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002), ischemic onset (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.005), aneurysms involving the vertebrobasilar junction (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.025), and GCS grade \u226412 before the procedure (\n                      <jats:italic>P<\/jats:italic>\n                      &amp;lt; 0.001) were risk factors for unfavorable clinical outcomes. Cumulative survival rates at 1, 3, and 5 years were 95.4%, 92.1%, and 87.9%, respectively. The cumulative complication-free survival rates were 72.1%, 68.3%, and 64.5%, respectively. Angiographic follow-up revealed complete occlusion in 71.7% (33\/46).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EVT for BTAs appears feasible and yields favorable clinical outcomes at the last follow-up, with reasonable cumulative survival rates at 1, 3, and 5 years. However, clinicians should be vigilant for procedure-related complications, particularly ischemic complications, which may lead to poor outcomes or death.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2025.1628676","type":"journal-article","created":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T16:06:51Z","timestamp":1756483611000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Complications and long-term outcomes after endovascular treatment of basilar trunk 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