{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:52:57Z","timestamp":1787755977518,"version":"build-2784847793"},"reference-count":29,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>While the novel C-reactive protein-albumin-lymphocyte (CALLY) index\u2014integrating inflammatory, nutritional, and immune markers\u2014has proven valuable for prognosis in various diseases, its utility in predicting outcomes for dysphagia patients is still unclear.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This retrospective cohort analysis utilized data sourced from the Dryad Digital Repository. The CALLY index (albumin \u00d7 lymphocyte count\/C-reactive protein \u00d7 104) was calculated. After logarithmic transformation (Ln-CALLY), the patients were divided into low Ln-CALLY group (\u2264 2.21) and high Ln-CALLY group (&amp;gt;2.21). All-cause mortality served as the primary endpoint. The association between Ln-CALLY and outcomes was evaluated using Kaplan-Meier analysis with log-rank testing and multivariable Cox proportional hazards regression. The dose-response relationship was evaluated by restricted cubic splines (RCS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study enrolled 253 elderly dysphagia patients. Analysis revealed Ln-CALLY as a significant predictor of all-cause mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The CALLY index shows promise as a predictor of mortality risk and long-term outcomes in older dysphagia patients.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fneur.2025.1650795","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T04:12:17Z","timestamp":1759205537000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Association between the C-reactive protein-albumin-lymphocyte (CALLY) index and mortality in elderly patients with dysphagia requiring nutritional 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