{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T06:37:02Z","timestamp":1762929422410,"version":"3.45.0"},"reference-count":89,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T00:00:00Z","timestamp":1762905600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>Transient ischemic attack or ischemic stroke within 6\u202fmonths is frequently associated with severe carotid stenosis. Carotid stent implantation is a widely employed treatment, but in-stent restenosis (ISR) is a dangerous postoperative complication. Many factors cause in-stent restenosis. Previous studies have indicated that stent type, drug use, patient-specific risk factors, levels of various factors in the patient\u2019s body, surgical procedures, and vascular physiological anatomy can all contribute to its occurrence. This review summarizes the key risk factors for ISR following CAS and briefly discusses related findings in intracranial artery stenting, aiming to inform clinical decision-making in neurointerventional practice.<\/jats:p>","DOI":"10.3389\/fneur.2025.1660202","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T06:32:55Z","timestamp":1762929175000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Research progress on risk factors for in-stent restenosis following cerebrovascular stent implantation"],"prefix":"10.3389","volume":"16","author":[{"given":"Haobo","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hifsa","family":"Bibi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongtu","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiwei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guofang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiabing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.21037\/atm-20-7490","article-title":"A narrative review of the pathophysiology of ischemic stroke in carotid plaques: a distinction versus a compromise between hemodynamic and embolic mechanism","volume":"9","author":"Mechtouff","year":"2021","journal-title":"Ann Transl Med"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1136\/svn-2022-001891","article-title":"Management of extracranial carotid artery stenosis during endovascular treatment for acute ischaemic stroke: results from the MR CLEAN registry","volume":"8","author":"Collette","year":"2023","journal-title":"Stroke Vasc Neurol"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1111\/ane.13062","article-title":"Carotid artery stenting: current state of evidence and future directions","volume":"139","author":"Lamanna","year":"2019","journal-title":"Acta Neurol Scand"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"366","DOI":"10.4103\/bc.bc_59_24","article-title":"Neurovascular management of intracranial internal carotid artery dissection post-carotid endarterectomy: A case report of an innovative approach","volume":"10","author":"Amatya","year":"2024","journal-title":"Brain Circulation"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1081","DOI":"10.1002\/14651858.CD001081.pub4","article-title":"Carotid endarterectomy for symptomatic carotid stenosis","volume":"9","author":"Rerkasem","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"465","DOI":"10.5114\/aic.2019.90221","article-title":"Severe, recurrent in-stent carotid restenosis: endovascular approach, risk factors. 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