{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:12:16Z","timestamp":1771920736071,"version":"3.50.1"},"reference-count":83,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:00:00Z","timestamp":1767916800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Study design<\/jats:title>\n                    <jats:p>Retrospective analysis of prognostic factors in traumatic cervical spinal cord injury (TCSCI) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Explore a novel approach for the prognosis assessment of TCSCI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis of clinical data was conducted on patients who underwent operation at Xi\u2019an Honghui Hospital between March 2016 and May 2023. The study included sex, age, hypertension, diabetes mellitus (DM), damage range, ossification of the posterior longitudinal ligament (OPLL), cervical spinal canal stenosis grading (CSCS), surgical timing, and postoperative complications (deep vein thrombosis, pulmonary complications, pressure ulcers, and urinary tract infections). A prognostic model was established by these differential factors and evaluating the sensitivity and specificity for predicting paralysis occurrence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Paralysis was found to be 4.009 times more likely in patients with DM compared to those without (95% CI: 1.250\u201312.863,\n                      <jats:italic>p\u202f=<\/jats:italic>\n                      0.020). Patients with diffuse damage had a 7.912 times higher likelihood of developing paralysis than those without diffuse damage (95% CI: 3.466\u201318.063,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). Patients with CSCS grade III had an 8.862 times higher likelihood of developing paralysis compared to those with grades 0, I, or II (95% CI: 3.280\u201323.946,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). The probability of paralysis with \u22652 postoperative complications was 4.625 times greater (95% CI, 1.107\u201319.323,\n                      <jats:italic>p\u202f=<\/jats:italic>\n                      0.036) than without complications. The probability of paralysis in patients with surgical times &amp;gt;3\u202fdays was 3.132 times greater (95% CI, 1.325\u20137.407,\n                      <jats:italic>p\u202f=<\/jats:italic>\n                      0.036) than within 3\u202fdays (95% CI, 1.325\u20137.407,\n                      <jats:italic>p\u202f=<\/jats:italic>\n                      0.009). The CSCS had the greatest effect on the prognosis of patients with paralysis, followed by the damage range. Sex, age, hypertension, and OPLL were not associated with prognosis (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prognosis of TCSCI is influenced by factors including DM, damage range, CSCS, surgical timing, and the number of postoperative complications. A clinical prognostic model was developed based on these prognostic factors, demonstrating a strong predictive capability for paralysis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2025.1684409","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T06:40:04Z","timestamp":1767940804000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Prognostic influences and prediction model construction for traumatic cervical spinal cord injury"],"prefix":"10.3389","volume":"16","author":[{"given":"Xin","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital, Medical College of Xi\u2019an Jiaotong University","place":["Xi'an, Shaanxi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-bo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University","place":["Xi'an, Shaanxi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xi-dan","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University","place":["Xi'an, Shaanxi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zi-lin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University","place":["Xi'an, Shaanxi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zheng-wei","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery, Honghui Hospital, Xi\u2019an Jiaotong University","place":["Xi'an, Shaanxi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, First Affiliated Hospital, Medical College of Xi\u2019an Jiaotong University","place":["Xi'an, Shaanxi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e474","DOI":"10.1016\/j.wneu.2018.11.190","article-title":"Comparing next-generation robotic technology with 3-dimensional computed tomography navigation Technology for the Insertion of posterior pedicle screws","volume":"123","author":"Khan","year":"2019","journal-title":"World Neurosurg"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/j.pmr.2020.03.005","article-title":"Updates of the international standards for neurologic classification of Spinal Cord Injury: 2015 and 2019","volume":"31","author":"Kirshblum","year":"2020","journal-title":"Phys Med Rehabil Clin N 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