{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T05:14:05Z","timestamp":1791522845968,"version":"4.3.4"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Acute stroke due to large vessel occlusion (LVO) is a serious complication of cardiac surgery or other cardiac interventions. Little is known about the epidemiological characteristics of affected patients, the temporal relationship between stroke detection and surgery\/intervention, the efficacy of mechanical thrombectomy, or the associated clinical outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed the demographic and thrombectomy characteristics and neurological outcomes of patients who underwent mechanical thrombectomy for acute ischemic stroke due to LVO after cardiac surgery\/intervention in a large academic heart center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From January 2018 to January 2022, a total of 39 patients underwent thrombectomy for acute ischemic stroke with LVO following cardiac surgery\/intervention. The median age was 66 years (IQR 57.5\u201376.0), and 13 patients (33.3%) were female. The highest frequency of thrombectomy for LVO-related stroke was observed after left ventricular assist device (LVAD) surgery (1.9%), followed by coronary artery bypass grafting (CABG) (0.20%), transcatheter aortic valve replacement (0.14%), and heart catheterization (0.04%). Stroke symptoms were detected in a wake-up constellation in 20 of the 39 patients (51.3%). Successful recanalization (TICI 2b\/3) was achieved in 83.8% of patients. At three months, 21.2% of patients attained a good functional outcome (modified Rankin scale score 0\u20132).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Thrombectomy for LVO stroke was conducted in a small subset of patients after cardiac surgery\/intervention. A large proportion of these strokes were detected in a wake-up constellation. Early detection, optimized acute neurological workup, and rapid thrombectomy may result in good functional outcomes. The establishment of a standardized diagnostic and treatment algorithm seems advisable for the optimization of acute stroke treatment in large heart centers.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2025.1705053","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:23:13Z","timestamp":1770268993000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Mechanical thrombectomy for acute ischemic stroke after cardiac surgery or intervention: a retrospective cohort analysis"],"prefix":"10.3389","volume":"16","author":[{"given":"Rosa M.","family":"Eckert","sequence":"first","affiliation":[{"name":"Department of Neurology and Experimental Neurology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt-Universit\u00e4t zu Berlin","place":["Berlin, 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Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuriy","family":"Hrytsyna","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charit\u00e9 (DHZC)","place":["Berlin, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evgenij","family":"Potapov","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charit\u00e9 (DHZC)","place":["Berlin, Germany"]},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site Berlin","place":["Berlin, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volkmar","family":"Falk","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charit\u00e9 (DHZC)","place":["Berlin, Germany"]},{"name":"DZHK (German Center for Cardiovascular Research), Partner Site 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