{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T11:54:41Z","timestamp":1761738881817,"version":"build-2065373602"},"reference-count":25,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Neurogenic claudication induced by degenerative lumbar spondylolisthesis (DLS) is a highly prevalent condition. In recent research, oblique lumbar interbody fusion with anterior fixation (OLIF-AF) has emerged as a favored minimally invasive approach for treating DLS. Nevertheless, there have been relatively few investigations that have compared this method with minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF), which has long been considered the standard technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To compare the clinical and radiological outcomes of OLIF-AF and MIS-TLIF in patients suffering from single-level, low-grade degenerative lumbar spondylolisthesis that leads to neurogenic claudication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective study of 57 patients who presented with neurogenic claudication secondary to single-level degenerative lumbar spondylolisthesis and underwent surgical treatment between May 2018 and December 2022. Of these 57 patients, 31 underwent oblique lumbar interbody fusion with anterior fixation (OLIF-AF) and 26 underwent minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). Every patient had a follow-up period of at least 2\u202fyears. The recorded and compared data included the perioperative indicators, follow-up outcomes, and imaging parameters between the two groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Preoperatively, the two groups exhibited a comparable baseline in demographic data and clinical characteristics, including visual analog scale (VAS) scores, Oswestry Disability Index (ODI), disc height (DH), intervertebral space angle (ISA), spinal canal cross-sectional area (CSA) and slip percentage (SP). Postoperatively, both groups exhibited significant improvements in VAS and ODI scores. The OLIF-AF group demonstrated superior clinical outcomes in terms of operative time (125.7\u202f\u00b1\u202f46.2\u202fmin vs. 202.1\u202f\u00b1\u202f66.4\u202fmin,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001), estimated blood loss (58.6\u202f\u00b1\u202f30.5\u202fmL vs. 143.5\u202f\u00b1\u202f46.8\u202fmL,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001), and length of hospital stay (8.6\u202f\u00b1\u202f2.5\u202fdays vs. 10.7\u202f\u00b1\u202f3.5\u202fdays,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.009) compared to the MIS-TLIF group. However, the incidence of perioperative complications did not differ significantly between the two groups (16.1% vs. 19.2%,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05). Radiographic assessment at the 2-year follow-up revealed significantly greater improvements in DH, ISA and CSA in the OLIF-AF group (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt; 0.05). At the 2-year follow-up, there were no significant differences between the two groups in SP (9.6 \u00b1 1.8 % vs. 9.4 \u00b1 1.6 %), interbody fusion rate (93.5% vs. 92.3%), or cage subsidence rate (3.2% vs. 3.8%) (all\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05). Although low back pain VAS, leg pain VAS, and ODI scores improved postoperatively in both groups compared with preoperative values, the OLIF-AF group showed greater improvement in low back pain VAS and ODI scores at 1\u202fweek and 3\u202fmonths postoperatively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Both OLIF-AF and MIS-TLIF are efficient in treating neurogenic claudication resulting from degenerative lumbar spondylolisthesis (DLS). Nevertheless, OLIF-AF is associated with a shorter operation duration, reduced surgical trauma, and faster early recovery, while maintaining long-term effectiveness and safety comparable to those of MIS-TLIF.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2025.1705975","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T05:30:25Z","timestamp":1761715825000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Two minimally invasive fusion techniques for neurogenic claudication caused by degenerative lumbar spondylolisthesis: a minimum 2-year follow-up study"],"prefix":"10.3389","volume":"16","author":[{"given":"Wei","family":"Cui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yehui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuangeng","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e057724","DOI":"10.1136\/bmjopen-2021-057724","article-title":"Non-operative treatment for lumbar spinal stenosis with neurogenic claudication: an updated systematic review","volume":"12","author":"Ammendolia","year":"2022","journal-title":"BMJ Open"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"893","DOI":"10.1016\/j.wneu.2024.10.123","article-title":"Decompression without fusion in patients with low-grade degenerative spondylolisthesis and stenosis: long-term patient-reported outcome","volume":"193","author":"van Grafhorst","year":"2025","journal-title":"World Neurosurg"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"1762","DOI":"10.1007\/s00586-023-07818-x","article-title":"Degenerative lumbar spondylolisthesis: review of current classifications and proposal of a novel classification system","volume":"33","author":"Rangwalla","year":"2024","journal-title":"Eur Spine J"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1055\/a-2297-4416","article-title":"Comparing OLIF combined with lateral screw fixation versus minimally invasive TLIF for treating single-level degenerative lumbar spondylolisthesis: a retrospective cohort study","volume":"86","author":"Li","year":"2025","journal-title":"J Neurol Surg A Cent Eur Neurosurg"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"E184","DOI":"10.1097\/BSD.0000000000000618","article-title":"Patient perceptions of minimally invasive versus open spine surgery","volume":"31","author":"Narain","year":"2018","journal-title":"Clin Spine Surg"},{"key":"ref6","first-page":"499","article-title":"Advances in minimally invasive spine surgery","volume":"49","author":"Foley","year":"2002","journal-title":"Clin Neurosurg"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1482067","DOI":"10.3389\/fsurg.2024.1482067","article-title":"Modified single-incision MIS-TLIF with expandable tubular assistance for degenerative lumbar spine diseases","volume":"11","author":"Hu","year":"2025","journal-title":"Front Surg"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"2049","DOI":"10.1016\/j.spinee.2021.07.006","article-title":"Long-term clinical outcome of minimally invasive versus open single-level transforaminal lumbar interbody fusion for degenerative lumbar diseases: a meta-analysis","volume":"21","author":"Heemskerk","year":"2021","journal-title":"Spine J"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"89","DOI":"10.4184\/asj.2012.6.2.89","article-title":"Complications and morbidities of Mini-open anterior retroperitoneal lumbar interbody fusion: oblique lumbar interbody fusion in 179 patients","volume":"6","author":"Silvestre","year":"2012","journal-title":"Asian Spine J"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"400","DOI":"10.1111\/os.13588","article-title":"Long-term clinical and imaging results of oblique lateral interbody fusion for degenerative lumbar spondylolisthesis: a systematic review and Meta-analysis","volume":"15","author":"Ma","year":"2023","journal-title":"Orthop Surg"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"456346","DOI":"10.1100\/2012\/456346","article-title":"Stand-alone lateral interbody fusion for the treatment of low-grade degenerative spondylolisthesis","volume":"2012","author":"Marchi","year":"2012","journal-title":"Sci World J"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"3467","DOI":"10.1007\/s00586-024-08401-8","article-title":"Oblique lumbar interbody fusion combined with anterolateral screw fixation and stress endplate augmentation for treating degenerative lumbar spondylolisthesis with osteoporosis","volume":"33","author":"Peng","year":"2024","journal-title":"Eur Spine J"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"536","DOI":"10.14245\/ns.2244954.477","article-title":"Perioperative clinical features and long-term prognosis after oblique lateral interbody fusion (OLIF), OLIF with anterolateral screw fixation, or OLIF with percutaneous pedicle fixation: a comprehensive treatment strategy for patients with lumbar degenerative disease","volume":"20","author":"Zhang","year":"2023","journal-title":"Neurospine"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1016\/j.spinee.2021.12.006","article-title":"Comparing the medium-term outcomes of lumbar interbody fusion via transforaminal and oblique approach in treating lumbar degenerative disc diseases","volume":"22","author":"Zhao","year":"2022","journal-title":"Spine J"},{"key":"ref15","doi-asserted-by":"publisher","first-page":"1410","DOI":"10.1097\/00007632-199506020-00014","article-title":"Anterior fresh frozen structural allografts in the thoracic and lumbar spine. Do they work if combined with posterior fusion and instrumentation in adult patients with kyphosis or anterior column defects?","volume":"20","author":"Bridwell","year":"1995","journal-title":"Spine"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1186\/s13018-024-04703-1","article-title":"Meta-analysis of the efficacy and safety of OLIF and TLIF in the treatment of degenerative lumbar spondylolisthesis","volume":"19","author":"Shi","year":"2024","journal-title":"J Orthop Surg Res"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"856022","DOI":"10.3389\/fneur.2022.856022","article-title":"Efficacy of single-position oblique lateral interbody fusion combined with percutaneous pedicle screw fixation in treating degenerative lumbar spondylolisthesis: a cohort study","volume":"13","author":"Cheng","year":"2022","journal-title":"Front Neurol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1186\/s12891-023-06985-8","article-title":"Clinical, radiographic and fusion comparison of oblique lumbar interbody fusion (OLIF) stand-alone and OLIF with posterior pedicle screw fixation in patients with degenerative spondylolisthesis","volume":"24","author":"Zhao","year":"2023","journal-title":"BMC Musculoskelet Disord"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1186\/s12891-024-07796-1","article-title":"Biomechanical changes of oblique lumbar interbody fusion with different fixation techniques in degenerative spondylolisthesis lumbar spine: a finite element analysis","volume":"25","author":"Tao","year":"2024","journal-title":"BMC Musculoskelet Disord"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"10225536241280191","DOI":"10.1177\/10225536241280191","article-title":"Comparative effectiveness of oblique lumbar interbody fusion with anterior screw fixation versus percutaneous pedicle screw fixation for treating lumbar degenerative diseases: a systematic review and meta-analysis","volume":"32","author":"Fatima","year":"2024","journal-title":"J Orthop Surg"},{"key":"ref21","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1186\/s12891-022-05855-z","article-title":"Restoration and maintenance of segment lordosis in oblique lumbar interbody fusion","volume":"23","author":"Gong","year":"2022","journal-title":"BMC Musculoskelet Disord"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"3263","DOI":"10.1111\/os.13882","article-title":"The influence of screw positioning on cage subsidence in patients with oblique lumbar interbody fusion combined with anterolateral fixation","volume":"15","author":"Wang","year":"2023","journal-title":"Orthop Surg"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"2319","DOI":"10.1007\/s00586-023-07761-x","article-title":"Risk factors for postoperative sympathetic chain dysfunction following oblique lateral lumbar interbody fusion: a multivariate analysis","volume":"32","author":"Zhao","year":"2023","journal-title":"Eur Spine J"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1055\/s-0044-1790515","article-title":"Perioperative complications of oblique lumbar interbody fusion (OLIF): 5 years of experience with OLIF","volume":"19","author":"Johnson","year":"2024","journal-title":"Asian J Neurosurg"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"e88","DOI":"10.1016\/j.wneu.2018.07.167","article-title":"Learning curve of minimally invasive surgery oblique lumbar interbody fusion for degenerative lumbar diseases","volume":"120","author":"Liu","year":"2018","journal-title":"World Neurosurg"}],"container-title":["Frontiers in Neurology"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2025.1705975\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T05:30:26Z","timestamp":1761715826000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fneur.2025.1705975\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,29]]},"references-count":25,"alternative-id":["10.3389\/fneur.2025.1705975"],"URL":"https:\/\/doi.org\/10.3389\/fneur.2025.1705975","relation":{},"ISSN":["1664-2295"],"issn-type":[{"type":"electronic","value":"1664-2295"}],"subject":[],"published":{"date-parts":[[2025,10,29]]},"article-number":"1705975"}}