{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T08:01:09Z","timestamp":1771920069379,"version":"3.50.1"},"reference-count":68,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003196","name":"Italian Ministry of Health","doi-asserted-by":"crossref","award":["RC2023-2024"],"award-info":[{"award-number":["RC2023-2024"]}],"id":[{"id":"10.13039\/501100003196","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>Neurogenic dysphagia affects up to 99% of patients with severe acquired brain injury (sABI) upon admission to intensive rehabilitation units (IRU) and increase clinical complications, resource use, and mortality. Conventional dysphagia rehabilitation often relies on active techniques, which are hardly applicable in non-collaborative patients, as is often the case with patients after sABI. In the absence of guidelines for dysphagia rehabilitation that consider the heterogeneity and clinical complexity of these patients, acupuncture and auriculotherapy (AA) could represent a valid intervention to be introduced into clinical practice. The aim of this multicenter double-blind, randomized, controlled trial is to evaluate the superiority of AA combined with conventional rehabilitation compared to conventional rehabilitation alone in improving dysphagia in non-cooperative vascular sABI patients. To this end, improvement in swallowing will be measured using both a clinical scale (Mann Assessment of Swallowing Ability-MASA) and a fiber optic endoscopic assessment (Pooling Score). Certain characteristics of patients admitted to IRUs after sABI, such as the rate and timing of decannulation, the infection rate, and the functional outcome measured by the Glasgow Outcome Scale\u2013Extended, will also be taken into consideration as secondary outcomes. By incorporating AA therapy into a personalized rehabilitation program, this study will examine its potential clinical benefits on dysphagia and the feasibility of this approach in the setting of early intensive rehabilitation for patients with sABI. AA could represent a low-cost, accessible bedside treatment complementary to standard rehabilitation, with no adverse effects, applicable in different clinical settings and at all stages of rehabilitation.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Clinical trial registration<\/jats:title>\n                    <jats:p>\n                      <jats:uri>https:\/\/clinicaltrials.gov\/ct2\/show\/NCT06888219<\/jats:uri>\n                      , NCT06888219.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2026.1724043","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T05:19:29Z","timestamp":1771910369000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["REhabilitation of Dysphagia with ACupuncture and auricular Therapy after severe acquired brain injury (REDACT study): a double-blind randomized controlled trial protocol"],"prefix":"10.3389","volume":"17","author":[{"given":"Martina","family":"Calamini","sequence":"first","affiliation":[{"name":"School of Specialization in Physical and Rehabilitation Medicine, University of Florence","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnese","family":"De Nisco","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Draghi","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Cecchi","sequence":"additional","affiliation":[{"name":"School of Specialization in Physical and Rehabilitation Medicine, University of Florence","place":["Florence, Italy"]},{"name":"Department of Experimental and Clinical Medicine, University of Florence","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Graziani","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]},{"name":"Head and Neck and Robotic Surgery, Azienda Ospedaliero Universitaria Careggi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonello","family":"Grippo","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]},{"name":"SODc Neurophysiopathology, Department Neuromuscolo-Scheletrico e degli Organi di Senso, Azienda Ospedaliero Universitaria Careggi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Macchi","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Maccanti","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annamaria","family":"Romoli","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvia","family":"Pancani","sequence":"additional","affiliation":[{"name":"IRCCS Fondazione Don Carlo Gnocchi","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelo","family":"Guido","sequence":"additional","affiliation":[{"name":"Regional Reference Center for Traditional Chinese Medicine, Corporate Coordination Center for Complementary Medicine, AUSL Toscana Centro","place":["Florence, 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