{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:54:51Z","timestamp":1793386491758,"version":"4.5.0"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:00:00Z","timestamp":1772668800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dizziness is common in older adults, and often presents a diagnostic challenge. Vestibular function declines with age, but the prevalence and diagnostic explanatory value of mild vestibular loss in isolation (i.e., the clinical diagnosis of \u201cpresbyvestibulopathy\u201d) remains uncertain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed consecutive patients aged \u2265 60\u202fyears in a subspecialty dizziness clinic who underwent clinical assessment (history, exam, videonystagmography) and horizontal canal video head impulse testing. We examined (i) the prevalence of vestibular loss (by laterality\/degree of loss), including across age groups, and (ii) the distribution of primary diagnoses and proportion attributable to presbyvestibulopathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 102 included patients (72% female, mean age 72.8\u202fyears), 70 (68.6%) had normal vestibular function. Seven (6.9%) had mild bilateral vestibular hypofunction (vestibulo-ocular reflex [VOR] gain of 0.6\u20130.8 bilaterally). A smaller number had more severe degrees of bilateral hypofunction: severe (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f6), and asymmetric (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f4). Right-sided VOR gain was highest in those aged 60\u201369\u202fyears (0.96), intermediate in those aged 70\u201379\u202fyears (0.89), and lowest in patients aged \u2265 80\u202fyears (0.77;\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001). Presbyvestibulopathy was uncommon as a final diagnosis across all age groups, with a total prevalence of 2.9% (\n                      <jats:italic>n<\/jats:italic>\n                      \u202f=\u202f3). All three of these patients had treatable comorbidities (e.g., anxiety).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>VOR gain by vHIT declines with age in patients with symptomatic dizziness; however, most patients aged \u2265 60 still demonstrate normal VOR gains. The diagnosis of presbyvestibulopathy is uncommon in older adults with dizziness; a more specific vestibular diagnosis is often more appropriate. Even in those with presbyvestibulopathy, treatment of comorbidities can improve symptoms and function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2026.1744462","type":"journal-article","created":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T05:25:16Z","timestamp":1772688316000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Presbyvestibulopathy: an uncommon cause of dizziness in the elderly"],"prefix":"10.3389","volume":"17","author":[{"given":"Tzu-Pu","family":"Chang","sequence":"first","affiliation":[{"name":"Department of Neurology, Neuro-Medical Scientific Center, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation","place":["Taichung, Taiwan"]},{"name":"Department of Neurology, School of Medicine, Tzu Chi University","place":["Hualien, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Hung","family":"Kuo","sequence":"additional","affiliation":[{"name":"Department of Research, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation","place":["Taichung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand K.","family":"Bery","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Harvard Medical School","place":["Boston, MA, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"38","DOI":"10.14336\/AD.2014.0128","article-title":"Dizziness and imbalance in the elderly: age-related decline in the vestibular system","volume":"6","author":"Iwasaki","year":"2015","journal-title":"Aging 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