{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T06:48:54Z","timestamp":1774594134795,"version":"3.50.1"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Poor quality of life (QOL) has emerged as a key morbidity in patients with idiopathic intracranial hypertension (IIH). This work aimed to develop and validate an IIH-specific quality of life assessment tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross-sectional study was conducted on 146 Egyptian and 156 Turkish patients with IIH. A 14-item questionnaire was created to assess QOL in those patients; Quality of Life in IIH patients questionnaire (QOLIH). The questionnaire items were hypothesized into two domains: one domain represents activities of daily living (ADL) (Q1-7 and Q12), and the other domain represents psycho-cognitive function (Q8-11, Q13, Q14). To assess the convergent validity of this questionnaire, the following tests were also employed: the Visual Analog Scale (VAS), Headache Impact Test-6 (HIT-6), Short Form-12 Health Survey (SF-12), and Low Vision Quality-of-Life Questionnaire (LVQOL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Confirmatory factor analysis (CFA) revealed that standardized factor loadings were generally acceptable (&amp;gt;0.60) for Q1-12. However, Q13 and Q14 consistently displayed weak loadings (&amp;lt;0.40), suggesting their removal. Cronbach\u2019s Alpha for the total score of the QOLIH questionnaire (Q1\u201312) in the Egyptian patients was 0.940, and in the Turkish patients, it was 0.938, indicating excellent internal consistency. There were statistically significant correlations of a strong degree between QOLIH total score and HIT-6, SF-12, and LVQOL total scores in Egyptian and Turkish patients (\n                      <jats:italic>r<\/jats:italic>\n                      coef.\u202f&amp;gt;\u202f0.7).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The final Arabic and Turkish versions of QOLIH questionnaire consist of 12 items. Both versions are valid and reliable tools that can be used in the assessment of QOL in IIH patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2026.1782362","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T05:19:47Z","timestamp":1774588787000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Validation of Quality of Life in Idiopathic Intracranial Hypertension (QOLIH) questionnaire"],"prefix":"10.3389","volume":"17","author":[{"given":"Mona","family":"Hussein","sequence":"first","affiliation":[{"name":"Department of Neurology, Beni-Suef University","place":["Beni-Suef, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amr","family":"Hassan","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cairo University","place":["Cairo, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona A. F.","family":"Nada","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cairo University","place":["Cairo, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeinab","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Public Health and Community Medicine, Beni-Suef University","place":["Beni-Suef, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rabia Gokcen","family":"Gozubatik-Celik","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bak\u0131rk\u00f6y Prof. Dr. Mazhar Osman Training and Research Hospital for Mental Health and Neurological Disorders, University of Health Sciences","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Banu","family":"Bayramoglu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Bak\u0131rk\u00f6y Prof. Dr. Mazhar Osman Training and Research Hospital for Mental Health and Neurological Disorders, University of Health Sciences","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilge","family":"Piri Cinar","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Samsun University","place":["Samsun, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aynur","family":"Ozge","sequence":"additional","affiliation":[{"name":"Headache Clinic","place":["Mersin, T\u00fcrkiye"]},{"name":"NOROM Neuroscience and Excellence Center","place":["Ankara, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amna","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beni-Suef University","place":["Beni-Suef, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mona","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Neurology, Beni-Suef University","place":["Beni-Suef, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arife \u00c7imen","family":"Atalar","sequence":"additional","affiliation":[{"name":"Department of Neurology, Istanbul Physical Therapy and Rehabilitation Training and Research Hospital","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevra","family":"\u00d6ks\u00fcz","sequence":"additional","affiliation":[{"name":"Department of Neurology, Faculty of Medicine, Mersin University","place":["Mersin, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet Hakan","family":"Bayram","sequence":"additional","affiliation":[{"name":"Department of Neurology, School of Medicine, Samsun University","place":["Samsun, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ehab Ahmed","family":"Hashish","sequence":"additional","affiliation":[{"name":"Neuropsychiatry Department, Suez Canal University","place":["Ismailia, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"May M.","family":"Fayez","sequence":"additional","affiliation":[{"name":"Neurology Department, El Mounira General Hospital","place":["Cairo, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rehab","family":"Magdy","sequence":"additional","affiliation":[{"name":"Department of Neurology, Cairo University","place":["Cairo, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1965","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1038\/s41582-023-00893-0","article-title":"Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms","volume":"19","author":"Yiangou","year":"2023","journal-title":"Nat Rev 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