{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:20:52Z","timestamp":1787026852742,"version":"build-2736575974"},"reference-count":19,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:p>\n                    Neuropsychiatric symptoms and executive dysfunction are highly prevalent in advanced Parkinson\u2019s disease (PD), particularly among institutionalized patients, yet evidence for structured rehabilitation in this population remains limited. We conducted a 3-month longitudinal pilot study in nine institutionalized patients with clinically established idiopathic PD according to Movement Disorder Society criteria. Participants received a weekly 45-min composite music-based recreational program incorporating stretching, perioral and pharyngeal exercises, and singing with coordinated movements. Mood was assessed using the Profile of Mood States 2 (POMS-2), and executive function was evaluated using the Frontal Assessment Battery (FAB) at baseline and post-intervention. Significant improvements were observed in POMS-2 subdomains of anger\u2013hostility (\n                    <jats:italic>p<\/jats:italic>\n                    \u202f=\u202f0.014), while Total Mood Disturbance and other subdomains showed a trend toward improvement. Executive function did not significantly improve at the group level (\n                    <jats:italic>p<\/jats:italic>\n                    \u202f=\u202f0.240); however, change in FAB was significantly correlated with change in Total Mood Disturbance (\n                    <jats:italic>r<\/jats:italic>\n                    \u202f=\u202f0.677,\n                    <jats:italic>p<\/jats:italic>\n                    \u202f=\u202f0.023). These findings suggest that a feasible music-based recreational program may modulate negative mood states in institutionalized patients with advanced PD and highlight a potential relationship between affective and executive changes warranting further investigation.\n                  <\/jats:p>","DOI":"10.3389\/fneur.2026.1821366","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T04:22:43Z","timestamp":1779164563000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of a 3-month composite music-based recreational program on mood and executive function in institutionalized patients with advanced Parkinson\u2019s disease"],"prefix":"10.3389","volume":"17","author":[{"given":"Haruna","family":"Aoki","sequence":"first","affiliation":[{"name":"Shizuku Works","place":["Toyonaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naho","family":"Shuto","sequence":"additional","affiliation":[{"name":"Super Court Co., Ltd.","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Hatsuse","sequence":"additional","affiliation":[{"name":"Shion Hospital, Medical Corporation Yoshikenkai","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsunori","family":"Azuma","sequence":"additional","affiliation":[{"name":"Super Court Co., Ltd.","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiyoshi","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Super Court Co., Ltd.","place":["Osaka, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Ikenaka","sequence":"additional","affiliation":[{"name":"Department of Neurology, Graduate School of Medicine, The University of Osaka","place":["Suita, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"185","DOI":"10.3389\/fneur.2015.00185","article-title":"Music therapy interventions in Parkinson's disease: the state-of-the-art","volume":"6","author":"Raglio","year":"2015","journal-title":"Front Neurol"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"11618","DOI":"10.3390\/ijerph182111618","article-title":"Music therapy and Parkinson\u2019s disease: a systematic review from 2015-2020","volume":"18","author":"Machado Sotomayor","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.1016\/j.parkreldis.2015.09.005","article-title":"Rehabilitation for Parkinson's disease: current outlook and future 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