{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T04:51:12Z","timestamp":1782449472650,"version":"3.54.5"},"reference-count":41,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Endolymphatic hydrops (EH), Meni\u00e8re\u2019s disease (MD) pathological hallmark, is visualized via 3 T delayed phase MRI. This study examines MRI correlations between EH severity and migraine brain biomarkers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective review of 144 inner ear MRI scans yielded 108 patients with confirmed EH. Two blinded radiologists graded EH, assessed migraine markers (white matter lesions (WML), frontal predominance of WML, enlarged perivascular spaces), and measured cranial nerve volumes. Binary logistic regression tested associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Mean age 53.6\u202f\u00b1\u202f15.8\u202fyears (56.5% female). Grade 2 vestibular EH predominated bilaterally; grade 2 cochlear EH affected 34\u201343%. No EH associations with migraine biomarkers or cranial nerve volumes were found (all\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;gt;\u202f0.05). Left vestibular EH grade 1 linked to sudden hearing loss (OR 5.205,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.018); left cochlear EH grade 1 to aural fullness (OR 5.019,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.016).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EH severity was not associated with established migraine MRI biomarkers in this cohort. These findings support the concept that EH and migraine-related structural brain changes may represent distinct imaging phenomena.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2026.1882444","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T04:34:14Z","timestamp":1782448454000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Endolymphatic hydrops in patients with migraine: a correlative study"],"prefix":"10.3389","volume":"17","author":[{"given":"Anne R. J.","family":"P\u00e9port\u00e9","sequence":"first","affiliation":[{"name":"Department of Radiology, Cantonal Hospital Frauenfeld","place":["Frauenfeld, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Sch\u00f6n","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cantonal Hospital M\u00fcnsterlingen","place":["M\u00fcnsterlingen, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustav","family":"Andreisek","sequence":"additional","affiliation":[{"name":"Department of Radiology, Cantonal Hospital M\u00fcnsterlingen","place":["M\u00fcnsterlingen, Switzerland"]},{"name":"Institute of Diagnostic and Interventional Radiology, University of Zurich","place":["Zurich, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jatta","family":"Berberat","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Cantonal Hospital Aarau","place":["Aarau, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franca","family":"Wagner","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Neuroradiology, Cantonal Hospital Aarau","place":["Aarau, Switzerland"]},{"name":"Department of Otorhinolaryngology and Head and Neck Surgery, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern","place":["Bern, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"e539","DOI":"10.1097\/MAO.0000000000001479","article-title":"Meni\u00e8re and friends: imaging and classification of hydropic ear disease","volume":"38","author":"G\u00fcrkov","year":"2017","journal-title":"Otol 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