{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T21:32:07Z","timestamp":1793309527118,"version":"4.5.0"},"reference-count":26,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Persistent apogeotropic positional nystagmus of the lateral semicircular canal, often classified as atypical lateral semicircular canal (SCC) BPPV (alBPPV), may occur without typical positional nystagmus or response to repositioning maneuvers, in the absence of neurological disease. We aimed to describe its clinical and radiological features and investigate the occurrence and clinical correlates of utricular\/saccular atelectasis on delayed 3D-FLAIR MRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Retrospective single-center study in a tertiary referral center. Patients underwent clinical, vestibular, auditory and electrophysiological assessment, including videonystagmography, video head impulse testing, and delayed 3D-FLAIR MRI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Thirty-two patients (mean age 68\u202fyears, vertigo duration 6.8\u202fyears) were included. Apogeotropic nystagmus persisted in 75%, with 50% meeting cupulolithiasis criteria. Geotropic conversion occurred in 15, and 10% showed no nystagmus. Vestibular investigations did not reveal a consistent or homogeneous vestibular deficit pattern. No consistent auditory abnormality was identified. Vibration-induced and head-shaking nystagmus were present in 30 and 50%, respectively, with kinetic hyporeflexia in 30%. Among patients with interpretable delayed 3D-FLAIR MRI, vestibular atelectasis was identified in approximately 60%. No significant clinical, audiological, or vestibular differences were found between patients with and without atelectasis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Persistent apogeotropic positional nystagmus involving the lateral SCC in the absence of neurological signs may represent a heterogeneous vestibular disorder. Vestibular atelectasis was commonly observed among patients with interpretable delayed 3D-FLAIR MRI, although its clinical and pathophysiological significance remains uncertain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fneur.2026.1890082","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T04:21:54Z","timestamp":1786076514000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Persistent apogeotropic positional nystagmus of the lateral semicircular canal: clinical features and association with vestibular atelectasis on delayed 3D-FLAIR MRI"],"prefix":"10.3389","volume":"17","author":[{"given":"Louis","family":"Calvet","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, CHU Reims, University of Reims Champagne-Ardenne","place":["Reims, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Regrain","sequence":"additional","affiliation":[{"name":"Department of Dizziness, Balance and Gait Assessment and Rehabilitation (CERVEM), Courlancy Group \u2013 Les Bleuets Polyclinic","place":["Reims, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Seidermann","sequence":"additional","affiliation":[{"name":"Department of Dizziness, Balance and Gait Assessment and Rehabilitation (CERVEM), Courlancy Group \u2013 Les Bleuets Polyclinic","place":["Reims, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Labrousse","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, CHU Reims, University of Reims Champagne-Ardenne","place":["Reims, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Dubernard","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, CHU Reims, University of Reims Champagne-Ardenne","place":["Reims, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,8,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1136\/jnnp.2006.100420","article-title":"Epidemiology of benign paroxysmal positional vertigo: a population based study","volume":"78","author":"von Brevern","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"105","DOI":"10.3233\/VES-150553","article-title":"Benign paroxysmal positional vertigo: diagnostic criteria: consensus document of the Committee for the Classification of vestibular disorders of the B\u00e1r\u00e1ny society","volume":"25","author":"Von Brevern","year":"2015","journal-title":"VES"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1159\/000276052","article-title":"Benign paroxysmal vertigo of the horizontal canal","volume":"51","author":"Pagnini","year":"1989","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1056\/NEJMcp1309481","article-title":"Clinical practice. 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