{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T12:13:40Z","timestamp":1788956020519,"version":"build-2803163510"},"reference-count":47,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Neurol."],"abstract":"\n Objective<\/jats:title>\n To compare the treatment efficacy of the Epley maneuver and the 360\u00b0 maneuver in a cohort diagnosed with posterior benign paroxysmal positional vertigo (BPPV) using a mechanical rotation chair (MRC).<\/jats:p>\n <\/jats:sec>\n \n Study design<\/jats:title>\n Open-label parallel group randomized controlled trial.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n Tertiary university hospital-based outpatient clinic.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n \n Adults (\n n<\/jats:italic>\n \u202f=\u202f102) diagnosed with unilateral posterior BPPV.\n <\/jats:p>\n <\/jats:sec>\n \n Intervention(s)<\/jats:title>\n Participants were randomized to treatment with either the Epley- or the 360\u00b0 maneuver. Follow-up visits were scheduled biweekly until treatment was successful or up to five treatments were given. By use of questionnaires, patient-reported outcome measures were assessed at baseline and after successful treatment. Subjective recurrences were assessed at 3- and 6-month follow-up questionnaires.<\/jats:p>\n <\/jats:sec>\n \n Main outcome measure(s)<\/jats:title>\n Primary outcome: treatment success after one treatment. Secondary outcomes: number of treatments to obtain treatment success, Dizziness Handicap Inventory (DHI), visual analogue scale (VAS) of vertigo, maneuver tolerability, and subjective recurrence.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Treatment success after one treatment was comparable between the groups (risk difference (RD): \u22120.12 (95% confidence interval (CI): \u22120.32, 0.07)). The cumulative probability of treatment success across treatments showed no clear difference between groups (hazard ratio: 0.77, 95% CI: 0.50, 1.21). Both groups showed clinically meaningful improvements in DHI and VAS of vertigo, with no between-group differences. Subjective recurrence rates were also similar.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Epley- and 360\u00b0 maneuvers with an MRC demonstrated similar treatment efficacy across objective and patient-reported outcomes, suggesting flexibility in the maneuver choice. Further research should investigate optimization of treatment protocols and long-term follow-up regarding recurrence patterns.<\/jats:p>\n <\/jats:sec>\n \n Clinical trial registration<\/jats:title>\n \n https:\/\/clinicaltrials.gov\/<\/jats:ext-link>\n , identifier NCT05834452.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.3389\/fneur.2026.1909757","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T12:02:27Z","timestamp":1788955347000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Epley maneuver versus 360\u00b0 maneuver for treatment of posterior canal benign paroxysmal positional vertigo in a mechanical rotation chair: a randomized controlled trial"],"prefix":"10.3389","volume":"17","author":[{"given":"Malene","family":"Hentze","sequence":"first","affiliation":[{"name":"Balance and Dizziness Center, Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital","place":["Aalborg, Denmark"]},{"name":"Department of Clinical Medicine, Aalborg University","place":["Aalborg, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan Dupont","family":"Hougaard","sequence":"additional","affiliation":[{"name":"Balance and Dizziness Center, Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital","place":["Aalborg, Denmark"]},{"name":"Department of Clinical Medicine, Aalborg University","place":["Aalborg, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman","family":"Kingma","sequence":"additional","affiliation":[{"name":"Balance and Dizziness Center, Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Aalborg University Hospital","place":["Aalborg, Denmark"]},{"name":"Department of Clinical Medicine, Aalborg University","place":["Aalborg, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1136\/jnnp.2006.100420","article-title":"Epidemiology of benign paroxysmal positional vertigo: a population based study","volume":"78","author":"Von Brevern","year":"2007","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1080\/16513860510028310","article-title":"Epidemiological data from 2270 PPV patients","volume":"3","author":"Caruso","year":"2005","journal-title":"Audiol Med"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"328","DOI":"10.14639\/0392-100X-1121","article-title":"Italian survey on benign paroxysmal positional vertigo","volume":"37","author":"Messina","year":"2017","journal-title":"Acta Otorhinolaryngol 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