{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:11:40Z","timestamp":1788999100136,"version":"build-2803163510"},"reference-count":72,"publisher":"Frontiers Media SA","content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Hum. Neurosci."],"DOI":"10.3389\/fnhum.2016.00341","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T15:59:23Z","timestamp":1467215963000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":76,"title":["Impact of Multiple Factors on the Degree of Tinnitus Distress"],"prefix":"10.3389","volume":"10","author":[{"given":"Petra","family":"Br\u00fcggemann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka J.","family":"Szczepek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Rose","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"McKenna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Olze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Mazurek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2016,6,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1080\/13548500512331315389","article-title":"Dimensions of perfectionism and tinnitus distress","volume":"10","author":"Andersson","year":"2005","journal-title":"Psychol. Health Med."},{"key":"B2","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/jclp.10243","article-title":"Internet-based cognitive behavioral therapy for tinnitus","volume":"60","author":"Andersson","year":"2004","journal-title":"J. Clin. Psychol."},{"key":"B3","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3109\/00206099809072971","article-title":"Tinnitus masking and depression","volume":"37","author":"Andersson","year":"1998","journal-title":"Audiology"},{"key":"B4","doi-asserted-by":"publisher","first-page":"S106","DOI":"10.1080\/14992020802301670","article-title":"Understanding tinnitus distress: introducing the concepts of moderators and mediators","volume":"47","author":"Andersson","year":"2008","journal-title":"Int. J. Audiol."},{"key":"B5","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1176\/appi.psy.51.1.29","article-title":"The distressed (Type D) personality is independently associated with tinnitus: a case-control study","volume":"51","author":"Bartels","year":"2010a","journal-title":"Psychosomatics"},{"key":"B6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1097\/MAO.0b013e3181bc3dd1","article-title":"The impact of Type D personality on health-related quality of life in tinnitus patients is mainly mediated by anxiety and depression","volume":"31","author":"Bartels","year":"2010b","journal-title":"Otol. Neurotol."},{"key":"B7","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1007\/s00106-008-1721-2","article-title":"[The role of the cervical spine and the craniomandibular system in the pathogenesis of tinnitus. Somatosensory tinnitus]","volume":"56","author":"Biesinger","year":"2008","journal-title":"HNO"},{"key":"B8","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1111\/j.1600-0447.1998.tb10088.x","article-title":"The relationship between coping style and burden in the carers of relatives with schizophrenia","volume":"98","author":"Budd","year":"1998","journal-title":"Acta Psychiatr. Scand."},{"key":"B9","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/S0022-3999(96)00171-7","article-title":"Tinnitus coping style and its relationship to tinnitus severity and emotional distress","volume":"41","author":"Budd","year":"1996","journal-title":"J. Psychosom. Res."},{"key":"B10","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1038\/nrendo.2009.106","article-title":"Stress and disorders of the stress system","volume":"5","author":"Chrousos","year":"2009","journal-title":"Nat. Rev. Endocrinol."},{"key":"B11","doi-asserted-by":"publisher","first-page":"634","DOI":"10.1097\/AUD.0b013e31821106dd","article-title":"Catastrophizing and fear of tinnitus predict quality of life in patients with chronic tinnitus","volume":"32","author":"Cima","year":"2011","journal-title":"Ear Hear."},{"key":"B12","doi-asserted-by":"publisher","first-page":"8075","DOI":"10.1073\/pnas.1018466108","article-title":"Phantom percepts: tinnitus and pain as persisting aversive memory networks","volume":"108","author":"De Ridder","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"B13","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1016\/j.jad.2014.10.063","article-title":"Evaluation of Computerized Adaptive Tests (CATs) for longitudinal monitoring of depression, anxiety, and stress reactions","volume":"190","author":"Devine","year":"2016","journal-title":"J. Affect. Disord"},{"issue":"53","key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fnsys.2012.00053","article-title":"The neuroscience of tinnitus: understanding abnormal and normal auditory perception","volume":"6","author":"Eggermont","year":"2012","journal-title":"Front. Syst. Neurosci."},{"key":"B15","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1097\/01.psy.0000151491.80178.78","article-title":"The Perceived Stress Questionnaire (PSQ) reconsidered: validation and reference values from different clinical and healthy adult samples","volume":"67","author":"Fliege","year":"2005","journal-title":"Psychosom. Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/1472-6815-2-3","article-title":"Long-term reductions in tinnitus severity","volume":"2","author":"Folmer","year":"2002","journal-title":"BMC Ear Nose Throat Disord."},{"key":"B17","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1080\/16513860801959100","article-title":"Pilot study to evaluate psychiatric co-morbidity in tinnitus patients with and without hyperacusis","volume":"6","author":"Goebel","year":"2008","journal-title":"Audiol. Med."},{"key":"B18","first-page":"166","article-title":"[The tinnitus questionnaire. A standard instrument for grading the degree of tinnitus. Results of a multicenter study with the tinnitus questionnaire]","volume":"42","author":"Goebel","year":"1994","journal-title":"HNO"},{"key":"B19","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/0022-3999(91)90033-K","article-title":"Anxiety and depression in tinnitus sufferers","volume":"35","author":"Halford","year":"1991","journal-title":"J. Psychosom. Res."},{"key":"B20","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1080\/14992020400050030","article-title":"Tinnitus impairs cognitive efficiency","volume":"43","author":"Hallam","year":"2004","journal-title":"Int. J. Audiol."},{"key":"B21","doi-asserted-by":"publisher","first-page":"e37733","DOI":"10.1371\/journal.pone.0037733","article-title":"Tinnitus severity is reduced with reduction of depressive mood\u2013a prospective population study in Sweden","volume":"7","author":"Hebert","year":"2012","journal-title":"PLoS ONE"},{"key":"B22","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1044\/1092-4388(2005\/084)","article-title":"General review of tinnitus: prevalence, mechanisms, effects, and management","volume":"48","author":"Henry","year":"2005","journal-title":"J. Speech Lang. Hear. Res."},{"key":"B23","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1055\/s-0042-1748040","article-title":"Psychoacoustic measures of tinnitus","volume":"11","author":"Henry","year":"2000","journal-title":"J. Am. Acad. Audiol."},{"key":"B24","first-page":"85","article-title":"Coping with tinnitus: two studies of psychological and audiological characteristics of patients with high and low tinnitus-related distress","volume":"1","author":"Henry","year":"1995","journal-title":"Int. Tinnitus J."},{"key":"B25","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1007\/s00106-008-1723-0","article-title":"[Neurootologic and psychosomatic habituation therapy. Treatment approaches in chronic tinnitus]","volume":"56","author":"Hesse","year":"2008","journal-title":"HNO"},{"key":"B26","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1080\/14992020802635325","article-title":"The role of anxiety sensitivity and behavioral avoidance in tinnitus disability","volume":"48","author":"Hesser","year":"2009","journal-title":"Int. J. Audiol."},{"key":"B27","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/0022-3999(92)90070-I","article-title":"A psychometric study of complaints in chronic tinnitus","volume":"36","author":"Hiller","year":"1992","journal-title":"J. Psychosom. Res."},{"key":"B28","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1159\/000106482","article-title":"When tinnitus loudness and annoyance are discrepant: audiological characteristics and psychological profile","volume":"12","author":"Hiller","year":"2007","journal-title":"Audiol. Neurootol."},{"key":"B29","first-page":"27","article-title":"Testing the invariance and hierarchy of a multidimensional model of mood by means of repeated measurement with student and patient samples","volume":"2","author":"Hoerhold","year":"1993","journal-title":"Z. Med. Psychol."},{"key":"B30","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/S0149-7634(03)00071-X","article-title":"The emotional ear in stress","volume":"27","author":"Horner","year":"2003","journal-title":"Neurosci. Biobehav. Rev."},{"key":"B31","first-page":"68","article-title":"Tinnitus retraining therapy","volume":"33","author":"Jastreboff","year":"1999","journal-title":"Br. J. Audiol."},{"key":"B32","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1080\/16506073.2012.717301","article-title":"The role of fear-avoidance cognitions and behaviors in patients with chronic tinnitus","volume":"42","author":"Kleinstauber","year":"2013","journal-title":"Cogn. Behav. Ther."},{"key":"B33","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.heares.2012.02.009","article-title":"Neuronal connectivity and interactions between the auditory and limbic systems. Effects of noise and tinnitus","volume":"288","author":"Kraus","year":"2012","journal-title":"Hear. Res."},{"key":"B34","first-page":"Doc07","article-title":"Do patient characteristics predict outcome in the outpatient treatment of chronic tinnitus?","volume":"3","author":"Kroner-Herwig","year":"2006","journal-title":"Psychosoc. Med."},{"key":"B35","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.genhosppsych.2004.08.008","article-title":"Psychosocial and personality predictors of tinnitus-related distress","volume":"27","author":"Langenbach","year":"2005","journal-title":"Gen. Hosp. Psychiatry"},{"key":"B36","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1185\/03007995.2011.595781","article-title":"A review of tinnitus symptoms beyond \u2018ringing in the ears\u2019: a call to action","volume":"27","author":"Langguth","year":"2011","journal-title":"Curr. Med. Res. Opin."},{"key":"B37","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.neuron.2010.12.002","article-title":"Dysregulation of limbic and auditory networks in tinnitus","volume":"69","author":"Leaver","year":"2011","journal-title":"Neuron"},{"key":"B38","doi-asserted-by":"publisher","first-page":"864","DOI":"10.3346\/jkms.2004.19.6.864","article-title":"Roles of cognitive characteristics in tinnitus patients","volume":"19","author":"Lee","year":"2004","journal-title":"J. Korean Med. Sci."},{"key":"B39","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1076\/jcen.23.1.121.1223","article-title":"The role of functional neuroimaging in the neuropsychology of depression","volume":"23","author":"Liotti","year":"2001","journal-title":"J. Clin. Exp. Neuropsychol."},{"key":"B40","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/0378-5955(95)00172-7","article-title":"Combined effects of adrenalectomy and noise exposure on compound action potentials, endocochlear potentials and endolymphatic potassium concentrations","volume":"91","author":"Ma","year":"1995","journal-title":"Hear. Res."},{"key":"B41","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.heares.2009.10.006","article-title":"Stress induces transient auditory hypersensitivity in rats","volume":"259","author":"Mazurek","year":"2010a","journal-title":"Hear. Res."},{"key":"B42","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1016\/j.neulet.2012.08.019","article-title":"Exposure of Wistar rats to 24-h psycho-social stress alters gene expression in the inferior colliculus","volume":"527","author":"Mazurek","year":"2012","journal-title":"Neurosci. Lett."},{"key":"B43","doi-asserted-by":"publisher","first-page":"3071","DOI":"10.3390\/ijerph7083071","article-title":"The more the worse: the grade of noise-induced hearing loss associates with the severity of tinnitus","volume":"7","author":"Mazurek","year":"2010b","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"196","key":"B44","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2014.00196","article-title":"A scientific cognitive-behavioral model of tinnitus: novel conceptualizations of tinnitus distress","volume":"5","author":"McKenna","year":"2014","journal-title":"Front. Neurol."},{"key":"B45","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.genhosppsych.2013.02.008","article-title":"The influence of psychological factors on tinnitus severity","volume":"35","author":"Milerova","year":"2013","journal-title":"Gen. Hosp. Psychiatry"},{"key":"B46","doi-asserted-by":"publisher","first-page":"S80","DOI":"10.1016\/j.neuroimage.2007.03.054","article-title":"Brain imaging of neuropathic pain","volume":"37","author":"Moisset","year":"2007","journal-title":"Neuroimage"},{"key":"B47","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1007\/s00038-005-4090-6","article-title":"[The version 2.0 of the SF-36 health survey: results of a population-representative study]","volume":"50","author":"Morfeld","year":"2005","journal-title":"Soz. Praventivmed."},{"key":"B48","doi-asserted-by":"publisher","first-page":"640","DOI":"10.1097\/AUD.0b013e31825069e8","article-title":"Generational differences in the reporting of tinnitus","volume":"33","author":"Nondahl","year":"2012","journal-title":"Ear Hear."},{"key":"B49","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1055\/s-2004-814235","article-title":"[Predictors and mechanisms of tinnitus distress - a longitudinal analysis]","volume":"83","author":"Olderog","year":"2004","journal-title":"Laryngorhinootologie"},{"key":"B50","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1016\/j.heares.2015.08.014","article-title":"Tinnitus and anxiety disorders: a review","volume":"333","author":"Pattyn","year":"2016","journal-title":"Hear. Res"},{"key":"B51","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1007\/s00106-002-0750-5","article-title":"[Dysfunctions of the stomatognathic system in tinnitus patients compared to controls]","volume":"51","author":"Peroz","year":"2003","journal-title":"HNO"},{"key":"B52","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1007\/BF01537606","article-title":"The use of the Center for Epidemiologic Studies Depression Scale in adolescents and young adults","volume":"20","author":"Radloff","year":"1991","journal-title":"J. Youth Adolesc."},{"key":"B53","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1016\/j.neuron.2010.04.032","article-title":"Tuning out the noise: limbic-auditory interactions in tinnitus","volume":"66","author":"Rauschecker","year":"2010","journal-title":"Neuron"},{"key":"B54","first-page":"202","article-title":"[Mobile computer-assisted psychometric diagnosis. Economic advantages and results on test stability]","volume":"49","author":"Rose","year":"1999","journal-title":"Psychother. Psychosom. Med. Psychol."},{"key":"B55","first-page":"186","article-title":"Prevalence of signs and symptoms of craniomandibular disorders in tinnitus patients","volume":"4","author":"Rubinstein","year":"1990","journal-title":"J. Craniomandib. Disord."},{"key":"B56","doi-asserted-by":"publisher","first-page":"e27379","DOI":"10.1371\/journal.pone.0027379","article-title":"Does tinnitus distress depend on age of onset?","volume":"6","author":"Schlee","year":"2011a","journal-title":"PLoS ONE"},{"key":"B57","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/978-1-60761-145-5_20","article-title":"A global brain model of tinnitus","volume-title":"Textbook of Tinnitus","author":"Schlee","year":"2011b"},{"key":"B58","doi-asserted-by":"publisher","first-page":"2075","DOI":"10.1152\/jn.01083.2006","article-title":"Heschl's gyrus, posterior superior temporal gyrus, and mid-ventrolateral prefrontal cortex have different roles in the detection of acoustic changes","volume":"97","author":"Schonwiesner","year":"2007","journal-title":"J. Neurophysiol."},{"key":"B59","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1176\/appi.psy.41.4.347","article-title":"Psychological profile and somatic complaints between help-seeking and non-help-seeking tinnitus subjects","volume":"41","author":"Scott","year":"2000","journal-title":"Psychosomatics"},{"key":"B60","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1097\/AUD.0b013e31828149f2","article-title":"Gender and chronic tinnitus: differences in tinnitus-related distress depend on age and duration of tinnitus","volume":"34","author":"Seydel","year":"2013","journal-title":"Ear Hear."},{"key":"B61","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1159\/000363728","article-title":"Three years later: report on the state of well-being of patients with chronic tinnitus who underwent modified tinnitus retraining therapy","volume":"20","author":"Seydel","year":"2015","journal-title":"Audiol. Neurootol."},{"key":"B62","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1159\/000231632","article-title":"Long-term improvement in tinnitus after modified tinnitus retraining therapy enhanced by a variety of psychological approaches","volume":"15","author":"Seydel","year":"2010","journal-title":"Audiol. Neurootol."},{"key":"B63","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1055\/s-2003-40947","article-title":"[Psychosomatic stress factors in compensated and decompensated tinnitus]","volume":"53","author":"Stobik","year":"2003","journal-title":"Psychother. Psychosom. Med. Psychol."},{"key":"B64","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/j.neuropsychologia.2003.11.004","article-title":"Network for auditory intrinsic alertness: a PET study","volume":"42","author":"Sturm","year":"2004","journal-title":"Neuropsychologia"},{"key":"B65","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1080\/08870446.2013.828294","article-title":"Illness representations as mediators of the relationship between dispositional optimism and depression in patients with chronic tinnitus: a cross-sectional study","volume":"29","author":"Vollmann","year":"2013","journal-title":"Psychol. Health"},{"key":"B66","doi-asserted-by":"publisher","first-page":"e34583","DOI":"10.1371\/annotation\/96f457f9-3f48-4f88-a7f0-1d5e6067e7a5","article-title":"Tinnitus: distinguishing between subjectively perceived loudness and tinnitus-related distress","volume":"7","author":"Wallhausser-Franke","year":"2012","journal-title":"PLoS ONE"},{"key":"B67","doi-asserted-by":"publisher","first-page":"177","DOI":"10.3109\/14992027.2012.752111","article-title":"The role of catastrophizing in recent onset tinnitus: its nature and association with tinnitus distress and medical utilization","volume":"52","author":"Weise","year":"2013","journal-title":"Int. J. Audiol."},{"key":"B68","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1044\/jshr.3401.197","article-title":"Tinnitus reaction questionnaire: psychometric properties of a measure of distress associated with tinnitus","volume":"34","author":"Wilson","year":"1991","journal-title":"J. Speech Hear. Res."},{"key":"B69","first-page":"23","article-title":"Tinnitus cognitions questionnaire: development and psychometric properties of a measure of dysfunctional cognitions associated with tinnitus","volume":"4","author":"Wilson","year":"1998","journal-title":"Int. Tinnitus J."},{"key":"B70","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1007\/s00106-003-0939-2","article-title":"[Cognitive tinnitus desensitization: evidence-based and guideline-adherent habituation therapy for chronic tinnitus sensitization]","volume":"51","author":"Zenner","year":"2003","journal-title":"HNO"},{"key":"B71","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1007\/s11136-012-0156-0","article-title":"Psychological comorbidity in patients with chronic tinnitus: analysis and comparison with chronic pain, asthma or atopic dermatitis patients","volume":"22","author":"Zirke","year":"2013","journal-title":"Qual. Life Res."},{"key":"B72","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1176\/appi.psy.47.4.282","article-title":"Relationship between tinnitus severity and psychiatric disorders","volume":"47","author":"Zoger","year":"2006","journal-title":"Psychosomatics"}],"container-title":["Frontiers in Human Neuroscience"],"original-title":[],"deposited":{"date-parts":[[2022,7,2]],"date-time":"2022-07-02T11:18:16Z","timestamp":1656760696000},"score":1,"resource":{"primary":{"URL":"http:\/\/journal.frontiersin.org\/Article\/10.3389\/fnhum.2016.00341\/abstract"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,29]]},"references-count":72,"URL":"https:\/\/doi.org\/10.3389\/fnhum.2016.00341","relation":{},"ISSN":["1662-5161"],"issn-type":[{"value":"1662-5161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,29]]}}}