{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T23:48:40Z","timestamp":1789688920611,"version":"4.0.1"},"reference-count":61,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:00:00Z","timestamp":1677024000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21H03308"],"award-info":[{"award-number":["21H03308"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20K21770"],"award-info":[{"award-number":["20K21770"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22H04788"],"award-info":[{"award-number":["22H04788"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["21K19745"],"award-info":[{"award-number":["21K19745"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["19H01091"],"award-info":[{"award-number":["19H01091"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Hum. Neurosci."],"abstract":"<jats:p>Progressive supranuclear palsy (PSP) is characterized by recurrent falls caused by postural instability, and a backward gait is considered beneficial for postural instability. Furthermore, a recent approach for rehabilitation combined with gait-oriented synchronized stimulation using non-invasive transcranial patterned stimulation could be promising for balance function. Here, we present a case of PSP with backward gait training combined with gait-synchronized transcranial alternating current stimulation (tACS). A 70-year-old woman with PSP-Richardson\u2019s syndrome underwent backward gait training combined with synchronized cerebellar tACS. Initially, she underwent short-term intervention with combined training of backward gait with synchronized cerebellar tACS, asynchronized, or sham stimulation according to the N-of-1 study design. Synchronized tACS training demonstrated a decrease in postural instability, whereas asynchronized or sham stimulation did not. The additional long-term interventions of combined backward gait training with synchronized cerebellar tACS demonstrated further decrease in postural instability with improvements in gait speed, balance function, and fall-related self-efficacy in daily life. The present case describes a novel approach for motor symptoms in a patient with PSP. Backward gait training with synchronized cerebellar tACS may be a promising therapeutic approach.<\/jats:p>","DOI":"10.3389\/fnhum.2023.1082555","type":"journal-article","created":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:43:43Z","timestamp":1677026623000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":12,"title":["Case report: Backward gait training combined with gait-synchronized cerebellar transcranial alternating current stimulation in progressive supranuclear palsy"],"prefix":"10.3389","volume":"17","author":[{"given":"Atsushi","family":"Shima","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuki","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akari","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Omae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoaki","family":"Miyake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yui","family":"Nagamori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Miyata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Ohata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumie","family":"Ono","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Mima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoko","family":"Koganemaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2023,2,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","first-page":"11262","DOI":"10.1523\/JNEUROSCI.5867-12.2013","article-title":"Transcranial alternating current stimulation modulates large-scale cortical network activity by network resonance.","volume":"33","author":"Ali","year":"2013","journal-title":"J. Neurosci."},{"key":"B2","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1111\/evj.12813","article-title":"Abnormal locomotor muscle recruitment activity is present in horses with shivering and purkinje cell distal axonopathy.","volume":"50","author":"Aman","year":"2018","journal-title":"Equine Veter. J."},{"key":"B3","doi-asserted-by":"publisher","first-page":"1290","DOI":"10.1016\/j.brs.2019.05.017","article-title":"Stimulation over the cerebellum with a regular figure-of-eight coil induces reduced motor cortex inhibition in patients with progressive supranuclear palsy.","volume":"12","author":"Benussi","year":"2019","journal-title":"Brain Stimulat."},{"key":"B4","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.brs.2016.11.001","article-title":"Long term clinical and neurophysiological effects of cerebellar transcranial direct current stimulation in patients with neurodegenerative ataxia.","volume":"10","author":"Benussi","year":"2017","journal-title":"Brain Stimulat."},{"key":"B5","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1002\/mdc3.12879","article-title":"Falls in progressive supranuclear palsy.","volume":"7","author":"Brown","year":"2020","journal-title":"Movement Dis. Clin. Pract."},{"key":"B6","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1016\/j.brs.2013.07.003","article-title":"Theta burst stimulation modulates cerebellar-cortical connectivity in patients with progressive supranuclear palsy.","volume":"7","author":"Brusa","year":"2014","journal-title":"Brain Stimulat."},{"key":"B7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fneur.2022.801291","article-title":"Perspective: balance assessments in progressive supranuclear palsy: lessons learned.","volume":"13","author":"Dale","year":"2022","journal-title":"Front. Neurol."},{"key":"B8","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1093\/gerona\/glr019","article-title":"Development and initial validation of the iconographical falls efficacy scale.","volume":"66","author":"Delbaere","year":"2011","journal-title":"J. Gerontol. Series Biol. Sci. Med. Sci."},{"key":"B9","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1080\/10749357.2019.1641011","article-title":"Clinical application of backward walking training to improve walking function, balance, and fall-risk in acute stroke: a case series.","volume":"26","author":"DeMark","year":"2019","journal-title":"Top. Stroke Rehabilit."},{"key":"B10","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1038\/nrn2979","article-title":"The role of phase synchronization in memory processes.","volume":"12","author":"Fell","year":"2011","journal-title":"Nat. Rev. Neurosci."},{"key":"B11","doi-asserted-by":"publisher","first-page":"405","DOI":"10.18869\/nirp.bcn.8.5.405","article-title":"The effect of repetitive transcranial magnetic stimulation on postural stability after acute stroke: a clinical trial.","volume":"8","author":"Forogh","year":"2017","journal-title":"Basic Clin. Neurosci."},{"key":"B12","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/S0304-3940(97)00381-9","article-title":"Brain functional activity during gait in normal subjects: a SPECT study.","volume":"228","author":"Fukuyama","year":"1997","journal-title":"Neurosci. Lett."},{"key":"B13","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1093\/brain\/awm032","article-title":"A clinical rating scale for progressive supranuclear palsy.","volume":"130","author":"Golbe","year":"2007","journal-title":"Brain"},{"key":"B14","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1016\/j.gaitpost.2017.08.019","article-title":"Backward compared to forward over ground gait retraining have additional benefits for gait in individuals with mild to moderate parkinson\u2019s disease: a randomized controlled trial.","volume":"58","author":"Grobbelaar","year":"2017","journal-title":"Gait Posture"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-112-4-293","article-title":"The n -of-1 randomized controlled trial: clinical usefulness.","volume":"112","author":"Guyatt","year":"1990","journal-title":"Ann. Int. Med."},{"key":"B16","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1016\/S0003-9993(96)90063-5","article-title":"Fear of falling revisited.","volume":"77","author":"Hill","year":"1996","journal-title":"Arch. Phys. Med. Rehabilit."},{"key":"B17","doi-asserted-by":"publisher","first-page":"853","DOI":"10.1002\/mds.26987","article-title":"Clinical diagnosis of progressive supranuclear palsy: the movement disorder society criteria.","volume":"32","author":"H\u00f6glinger","year":"2017","journal-title":"Mov. Dis."},{"key":"B18","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1249\/JES.0000000000000000","article-title":"Steps forward in understanding backward gait: from basic circuits to rehabilitation.","volume":"42","author":"Hoogkamer","year":"2014","journal-title":"Exerc. Sport Sci. Rev."},{"key":"B19","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.gaitpost.2017.08.037","article-title":"Quick foot placement adjustments during gait are less accurate in individuals with focal cerebellar lesions.","volume":"58","author":"Hoogkamer","year":"2017","journal-title":"Gait Posture"},{"key":"B20","doi-asserted-by":"crossref","first-page":"485","DOI":"10.2522\/ptj.20080071","article-title":"The balance evaluation systems test (BESTest) to differentiate balance deficits.","volume":"89","author":"Horak","year":"2009","journal-title":"Phys. Ther."},{"key":"B21","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.pmrj.2017.12.011","article-title":"The role of rehabilitation in patients with progressive supranuclear palsy: a narrative review.","volume":"10","author":"Intiso","year":"2018","journal-title":"PM R"},{"key":"B22","doi-asserted-by":"crossref","first-page":"4791","DOI":"10.1111\/ejn.14919","article-title":"Gait-combined transcranial alternating current stimulation modulates cortical control of muscle activities during gait.","volume":"52","author":"Kitatani","year":"2020","journal-title":"Eur. J. Neurosci."},{"key":"B23","doi-asserted-by":"publisher","first-page":"2275","DOI":"10.1152\/jn.00665.2010","article-title":"Two aspects of feedforward postural control: anticipatory postural adjustments and anticipatory synergy adjustments.","volume":"105","author":"Klous","year":"2011","journal-title":"J. Neurophysiol."},{"key":"B24","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fnsys.2015.00154","article-title":"Two is more than one: how to combine brain stimulation rehabilitative training for functional recovery?","volume":"9","author":"Koganemaru","year":"2015","journal-title":"Front. Syst. Neurosci."},{"key":"B25","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.brs.2017.02.005","article-title":"Effects of vestibular rehabilitation combined with transcranial cerebellar direct current stimulation in patients with chronic dizziness: an exploratory study.","volume":"10","author":"Koganemaru","year":"2017","journal-title":"Brain Stimulat."},{"key":"B26","doi-asserted-by":"publisher","first-page":"3205","DOI":"10.1161\/STROKEAHA.119.025354","article-title":"Gait-synchronized rhythmic brain stimulation improves poststroke gait disturbance: a pilot study.","volume":"50","author":"Koganemaru","year":"2019","journal-title":"Stroke"},{"key":"B27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0208691","article-title":"Anodal transcranial patterned stimulation of the motor cortex during gait can induce activity-dependent corticospinal plasticity to alter human gait.","volume":"13","author":"Koganemaru","year":"2018","journal-title":"PLoS One"},{"key":"B28","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.neures.2019.12.003","article-title":"Cerebellar transcranial alternating current stimulation modulates human gait rhythm.","volume":"156","author":"Koganemaru","year":"2020","journal-title":"Neurosci. Res."},{"key":"B29","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1007\/s00401-020-02158-2","article-title":"Distribution patterns of tau pathology in progressive supranuclear palsy.","volume":"140","author":"Kovacs","year":"2020","journal-title":"Acta Neuropathol."},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.2340\/jrm.v53.1097","article-title":"Efficacy of repetitive transcranial magnetic stimulation for improving lower limb function in individuals with neurological disorders: a systematic review and meta-analysis of randomized sham-controlled trials.","volume":"54","author":"Krogh","year":"2022","journal-title":"J. Rehabilit. Med."},{"key":"B31","doi-asserted-by":"publisher","first-page":"1602","DOI":"10.1016\/j.neuroimage.2011.08.084","article-title":"Stride-time variability and sensorimotor cortical activation during walking.","volume":"59","author":"Kurz","year":"2012","journal-title":"NeuroImage"},{"key":"B32","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1097\/NPT.0b013e31821a620c","article-title":"Utility of the mini-BESTest, BESTest, and BESTest sections for balance assessments in individuals with parkinson disease.","volume":"35","author":"Leddy","year":"2011","journal-title":"J. Neurol. Phys. Ther."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.955893","article-title":"Effect of therapeutic exercise on the balance of patients with progressive supranuclear palsy: a pilot study.","volume":"13","author":"Matsuda","year":"2022","journal-title":"Front. Neurol."},{"key":"B34","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1111\/neup.12590","article-title":"Chameleons and mimics: progressive supranuclear palsy and corticobasal degeneration.","volume":"40","author":"Mimuro","year":"2020","journal-title":"Neuropathology"},{"key":"B35","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.1016\/j.clinph.2006.04.009","article-title":"Modeling the current distribution during transcranial direct current stimulation.","volume":"117","author":"Miranda","year":"2006","journal-title":"Clin. Neurophysiol."},{"key":"B36","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/0301-0082(87)90010-4","article-title":"Integration of posture and locomotion in acute decerebrate cats and in awake, freely moving cats.","volume":"28","author":"Mori","year":"1987","journal-title":"Prog. Neurobiol."},{"key":"B37","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1152\/jn.1999.82.1.290","article-title":"Stimulation of a restricted region in the midline cerebellar white matter evokes coordinated quadrupedal locomotion in the decerebrate cat.","volume":"82","author":"Mori","year":"1999","journal-title":"J. Neurophysiol."},{"key":"B38","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1177\/1073858404263517","article-title":"Cerebellar control of balance and locomotion.","volume":"10","author":"Morton","year":"2004","journal-title":"Neuroscientist"},{"key":"B39","doi-asserted-by":"publisher","first-page":"9107","DOI":"10.1523\/JNEUROSCI.2622-06.2006","article-title":"Cerebellar contributions to locomotor adaptations during splitbelt treadmill walking.","volume":"26","author":"Morton","year":"2006","journal-title":"J. Neurosci."},{"key":"B40","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.parkreldis.2018.05.006","article-title":"Effects of exercise on gait and motor imagery in people with parkinson disease and freezing of gait.","volume":"53","author":"Myers","year":"2018","journal-title":"Parkins. Related Dis."},{"key":"B41","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1016\/j.clinph.2013.10.008","article-title":"Brain activity during complex imagined gait tasks in parkinson disease.","volume":"125","author":"Peterson","year":"2014","journal-title":"Clin. Neurophysiol."},{"key":"B42","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1007\/s12311-021-01239-6","article-title":"Cerebellar RTMS in PSP: a double-blind sham-controlled study using mobile health technology.","volume":"20","author":"Pilotto","year":"2021","journal-title":"Cerebellum"},{"key":"B43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fnhum.2014.00475","article-title":"Cerebellar contribution to feedforward control of locomotion.","volume":"8","author":"Pisotta","year":"2014","journal-title":"Front. Hum. Neurosci."},{"key":"B44","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1016\/j.cub.2012.05.021","article-title":"The importance of timing in segregated theta phase-coupling for cognitive performance.","volume":"22","author":"Polan\u00eda","year":"2012","journal-title":"Curr. Biol."},{"key":"B45","doi-asserted-by":"crossref","first-page":"M28","DOI":"10.1093\/gerona\/50A.1.M28","article-title":"The activities-specific balance confidence (ABC) scale.","author":"Powell","year":"1995","journal-title":"J. Gerontol."},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2020.117044","article-title":"Accurate and robust whole-head segmentation from magnetic resonance images for individualized head modeling.","volume":"219","author":"Puonti","year":"2020","journal-title":"NeuroImage"},{"key":"B47","author":"Saturnino","year":"2019","journal-title":"SimNIBS 2.1: a comprehensive pipeline for individualized electric field modelling for transcranial brain stimulation."},{"key":"B48","doi-asserted-by":"publisher","first-page":"2413","DOI":"10.1002\/mds.23298","article-title":"Cerebellar dysfunction in progressive supranuclear palsy: a transcranial magnetic stimulation study.","volume":"25","author":"Shirota","year":"2010","journal-title":"Mov. Dis."},{"key":"B49","doi-asserted-by":"publisher","first-page":"1568","DOI":"10.1016\/j.arr.2022.101736","article-title":"Transcranial direct current stimulation for balance rehabilitation in neurological disorders: a systematic review and meta-analysis.","volume":"8","author":"Spiandor","year":"2022","journal-title":"Ageing Res. Rev."},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20060166","article-title":"Long-term locomotor training for gait and balance in a patient with mixed progressive supranuclear palsy and corticobasal degeneration.","volume":"87","author":"Steffen","year":"2007","journal-title":"Phys. Ther."},{"key":"B51","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1093\/ptj\/82.5.485","article-title":"Supported treadmill training for gait and balance in a patient with progressive supranuclear palsy.","volume":"82","author":"Suteerawattananon","year":"2002","journal-title":"Phys. Ther."},{"key":"B52","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1002\/mds.25669","article-title":"Neurophysiology of gait: from the spinal cord to the frontal lobe.","volume":"28","author":"Takakusaki","year":"2013","journal-title":"Mov. Dis."},{"key":"B53","doi-asserted-by":"publisher","first-page":"1","DOI":"10.14802\/jmd.16062","article-title":"Functional neuroanatomy for posture and gait control.","volume":"10","author":"Takakusaki","year":"2017","journal-title":"J. Mov. Dis."},{"key":"B54","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1007\/s002210100858","article-title":"Perturbed step initiation in cerebellar subjects: 2. modification of anticipatory postural adjustments.","volume":"141","author":"Timmann","year":"2001","journal-title":"Exp. Brain Res."},{"key":"B55","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1093\/geronj\/45.6.P239","article-title":"Falls efficacy as a measure of fear of falling.","volume":"45","author":"Tinetti","year":"1990","journal-title":"J. Gerontol."},{"key":"B56","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1002\/ana.410360117","article-title":"Suppression of motor cortical excitability by electrical stimulation over the cerebellum in ataxia.","volume":"36","author":"Ugawa","year":"1994","journal-title":"Ann. Neurol."},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-02928-3","article-title":"Direct effects of transcranial electric stimulation on brain circuits in rats and humans.","volume":"9","author":"V\u00f6r\u00f6slakos","year":"2018","journal-title":"Nat. Commun."},{"key":"B58","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1016\/j.neuroimage.2007.01.027","article-title":"Transcranial direct current stimulation: a computer-based human model study.","volume":"35","author":"Wagner","year":"2007","journal-title":"NeuroImage"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph19063370","article-title":"Backward walking training impacts positive effect on improving walking capacity after stroke: a meta-analysis.","volume":"19","author":"Wen","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.629323","article-title":"Systemic review on transcranial electrical stimulation parameters and EEG\/FNIRS features for brain DISEASES.","volume":"15","author":"Yang","year":"2021","journal-title":"Front. Neurosci."},{"key":"B61","article-title":"Balance and eye movement training to improve gait in people with progressive supranuclear palsy:","volume":"88","author":"Zampieri","year":"2008"}],"container-title":["Frontiers in Human Neuroscience"],"original-title":[],"link":[{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnhum.2023.1082555\/full","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,22]],"date-time":"2023-02-22T00:43:46Z","timestamp":1677026626000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.frontiersin.org\/articles\/10.3389\/fnhum.2023.1082555\/full"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,22]]},"references-count":61,"alternative-id":["10.3389\/fnhum.2023.1082555"],"URL":"https:\/\/doi.org\/10.3389\/fnhum.2023.1082555","relation":{},"ISSN":["1662-5161"],"issn-type":[{"value":"1662-5161","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,22]]},"article-number":"1082555"}}