{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:47:25Z","timestamp":1781106445480,"version":"3.54.1"},"reference-count":43,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Hum. Neurosci."],"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Dyke-Davidoff-Masson syndrome (DDMS) is a rare neurological disorder characterized by unilateral hemiparesis, facial asymmetry, severe epilepsy, and intellectual disability. While congenital DDMS is predominantly attributed to anterior circulation anomalies [e.g., internal carotid artery (ICA) or middle cerebral artery (MCA) hypoplasia], posterior circulation involvement remains unreported. Here, we present the first documented case of congenital DDMS resulting from a rare combination of hypoplastic left posterior cerebral artery (PCA) and ipsilateral fetal-type posterior communicating artery (FTP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 19-year-old male exhibited atypical DDMS manifestations: absence seizures, preserved motor function, and occipitotemporal cognitive deficits (MoCA: 20\/30). Neuroimaging revealed classic DDMS features. Angiography confirmed left PCA hypoplasia with FTP persistence, while CT perfusion demonstrated chronic left PCA hypoperfusion. Lamotrigine (100\u202fmg\/day) and regular cognition rehabilitative training resulted in good symptom control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case identifies PCA hypoplasia with FTP as a novel DDMS etiology, challenging the MCA\/ICA-centric paradigm. The \u201cposterior phenotype\u201d (absence seizures, preserved motor function, occipitotemporal cognitive deficits) expands DDMS heterogeneity. Multimodal imaging (angiography\/perfusion) is diagnostic gold-standard, while personalized therapy optimizes outcomes.<\/jats:p><\/jats:sec>","DOI":"10.3389\/fnhum.2025.1629156","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T11:23:35Z","timestamp":1757417015000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Case Report: Dyke-Davidoff-Masson syndrome resulting from a rare combination of hypoplastic left posterior cerebral artery and ipsilateral fetal-type posterior communicating artery"],"prefix":"10.3389","volume":"19","author":[{"given":"He","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huijuan","family":"Hua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingju","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongjun","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1001\/archneur.1987.00520140090024","article-title":"Cerebral hemiatrophy, hypoplasia of internal carotid artery, and intracranial aneurysm","volume":"44","author":"Afifi","year":"1987","journal-title":"Arch. 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