{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:03:51Z","timestamp":1789625031606,"version":"build-2803163510"},"reference-count":78,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T00:00:00Z","timestamp":1789603200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Hum. Neurosci."],"abstract":"<jats:p>\n                    Parkinson\u2019s disease is a progressive neurodegenerative disorder associated with substantial motor and non-motor impairments that significantly reduce functional independence and quality of life. While pharmacological treatments remain essential, they often fail to adequately address complex symptoms such as balance deficits, cognitive dysfunction, and reduced wellbeing. Multimodal, non-pharmacological interventions are therefore increasingly recognized as important complementary approaches. This study protocol introduces\n                    <jats:italic>NeuroDance,<\/jats:italic>\n                    a novel, structured dance-based intervention designed to target the multidimensional symptom profile of Parkinson\u2019s disease.\n                    <jats:italic>NeuroDance<\/jats:italic>\n                    integrates multiple dance styles\u2014including Country dance, Greek folk dance, Tango, and Polka\u2014with improvisational elements. By combining rhythmic auditory cueing, movement variability, social interaction, and internally generated movement, the intervention aims to promote motor learning, enhance neuroplasticity, and improve psychological wellbeing.\n                    <jats:italic>NeuroDance<\/jats:italic>\n                    is a multicenter quasi-experimental study conducted across four European countries. It consists of two sequential phases: a feasibility phase and an exploratory effectiveness phase. The feasibility phase uses a single-group pre\u2013post design to evaluate the acceptability, safety, adherence, and practical implementation of the intervention and assessment procedures. Findings from this phase will inform refinements of the intervention protocol and will be reported separately. The exploratory effectiveness phase uses a controlled pre\u2013post design including a\n                    <jats:italic>NeuroDance<\/jats:italic>\n                    intervention group and control group. The 18-week intervention is delivered twice weekly in group sessions and is adapted to participants\u2019 individual functional capacities. Primary outcomes include gait, mobility, coordination, balance, cognitive performance, quality of life and subjective wellbeing, while secondary outcomes encompass fear of falling, and disease-specific symptoms. In addition, selected centers assess neurophysiological adaptations using electroencephalography and magnetic resonance imaging to explore underlying neural mechanisms. By integrating diverse movement demands and emphasizing both externally cued and self-initiated motor activity,\n                    <jats:italic>NeuroDance<\/jats:italic>\n                    represents a conceptual advance beyond single-style dance interventions. This study protocol provides the methodological framework for evaluating the feasibility and preliminary effectiveness of\n                    <jats:italic>NeuroDance<\/jats:italic>\n                    in people with Parkinson\u2019s disease and will inform future controlled trials and implementation strategies.\n                  <\/jats:p>\n                  <jats:sec>\n                    <jats:title>Study protocol registration<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link>https:\/\/drks.de\/search\/en\/trial\/DRKS00038241\/details<\/jats:ext-link>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnhum.2026.1893119","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T05:33:25Z","timestamp":1789623205000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["NeuroDance: study protocol for a non-randomized multicenter study of a mixed-style dance intervention for people with Parkinson\u2019s disease"],"prefix":"10.3389","volume":"20","author":[{"given":"Kathrin","family":"Rehfeld","sequence":"first","affiliation":[{"name":"Faculty for Humanities, Institute of Sport Science, Otto von Guericke University","place":["Magdeburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Gro\u00df","sequence":"additional","affiliation":[{"name":"Faculty for Humanities, Institute of Sport Science, Otto von Guericke University","place":["Magdeburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"H\u00f6kelmann","sequence":"additional","affiliation":[{"name":"Faculty for Humanities, Institute of Sport Science, Otto von Guericke University","place":["Magdeburg, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Pelclov\u00e1","sequence":"additional","affiliation":[{"name":"Faculty of Physical Culture, Institute of Active Lifestyle, Palack\u00fd University Olomouc","place":["Olomouc, Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Harvanov\u00e1","sequence":"additional","affiliation":[{"name":"Faculty of Physical Culture, Department of Social Sciences in Kinanthropology, Palack\u00fd University Olomouc","place":["Olomouc, Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"\u0160lachtov\u00e1","sequence":"additional","affiliation":[{"name":"Faculty of Physical Culture, Department of Physiotherapy, Palack\u00fd University Olomouc","place":["Olomouc, Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Dupalov\u00e1","sequence":"additional","affiliation":[{"name":"Faculty of Physical Culture, Department of Physiotherapy, Palack\u00fd University Olomouc","place":["Olomouc, Czechia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xanthoula","family":"Charalampidou","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Science, University of Thessaly","place":["Volos, Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evangelos","family":"Mantsos","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Science, University of Thessaly","place":["Volos, Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasiliki","family":"Zisi","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sport Science, University of Thessaly","place":["Volos, Greece"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uros","family":"Marusic","sequence":"additional","affiliation":[{"name":"Science and Research Centre Koper, Institute for Kinesiology Research","place":["Koper, Slovenia"]},{"name":"Department of Health Sciences, Alma Mater Europaea University","place":["Maribor, Slovenia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manca","family":"Peskar","sequence":"additional","affiliation":[{"name":"Science and Research Centre Koper, Institute for Kinesiology Research","place":["Koper, Slovenia"]},{"name":"Biological Psychology and Neuroergonomics, Department of Psychology and Ergonomics, Faculty V: Mechanical Engineering and Transport Systems, Technische Universit\u00e4t Berlin","place":["Berlin, Germany"]},{"name":"Faculty of Education, University of Ljubljana","place":["Ljubljana, Slovenia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"S60","DOI":"10.1016\/j.parkreldis.2015.09.005","article-title":"Rehabilitation for Parkinson\u2019s disease: current outlook and future challenges","volume":"22","author":"Abbruzzese","year":"2016","journal-title":"Parkinsonism Relat. 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