{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:56:01Z","timestamp":1790751361946,"version":"4.1.0"},"reference-count":60,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Hum. Neurosci."],"abstract":"<jats:p>Motivational evaluation can generalize across diverse goals, while the incentive value of biologically relevant stimuli such as food is dynamically modulated by physiological need. The present study examined whether cross-category desirability evaluation under a non-deprived baseline condition and food incentive evaluation under experimentally manipulated Hunger and Satiety states show partially similar valuation-related neural responses within the same individuals. Participants underwent functional magnetic resonance imaging (fMRI) while completing two complementary experiments: an abstract desirability judgment task involving objects, events, and persons, and a food evaluation task conducted under Hunger and Satiety states. In the DESIRE experiment, neural responses associated with desirable versus undesirable judgments were examined across three semantic categories to identify candidate neural patterns related to abstract desirability evaluation. In the HUNGER experiment, analyses examined both baseline food incentive value and hunger-related increases in food desirability. Exploratory whole-brain analyses identified activation patterns involving medial frontal and cingulate valuation-related regions, including the medial prefrontal cortex (mPFC), anterior cingulate cortex (ACC), and medial orbitofrontal cortex (mOFC), during abstract desirability evaluation. Exploratory maps in baseline food incentive-value evaluation analysis also implicated medial frontal and cingulate valuation-related regions. In addition, food items whose desirability increased under hunger showed greater activation than rating-stable food items in the left inferior orbitofrontal cortex, together with visual, cerebellar, and sensorimotor regions. However, formal conjunction-null analyses, ROI-based convergence analyses, whole-brain overlap analyses, and permutation-based tests did not provide evidence for a statistically robust shared neural representation across abstract desirability and food valuation. These findings suggest that cross-category desirability evaluation and homeostatically modulated food incentive evaluation may involve partially overlapping valuation-related processes while remaining sensitive to semantic context and physiological state. The results provide preliminary support for the possibility that abstract motivational cognition may partially engage valuation-related processes that are also involved in physiological incentive evaluation.<\/jats:p>","DOI":"10.3389\/fnhum.2026.1909419","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:00:37Z","timestamp":1790748037000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring partially shared valuation-related neural responses between abstract desirability and food incentive evaluation"],"prefix":"10.3389","volume":"20","author":[{"given":"Renkai","family":"Chen","sequence":"first","affiliation":[{"name":"Taizhou College","place":["Taizhou, Zhejiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fufang","family":"Wang","sequence":"additional","affiliation":[{"name":"Research Institute of Foreign Languages, Bejing Foreign Studies University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1017\/S0140525X10000853","article-title":"Neural reuse: a fundamental organizational principle of the brain","volume":"33","author":"Anderson","year":"2010","journal-title":"Behav. 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Sci."},{"key":"ref8","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1017\/CBO9780511499968.007","volume-title":"Grounding Cognition","author":"Barsalou","year":"2005"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1016\/j.neuroimage.2013.02.063","article-title":"The valuation system: a coordinate-based meta-analysis of BOLD fMRI experiments examining neural correlates of subjective value","volume":"76","author":"Bartra","year":"2013","journal-title":"NeuroImage"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1016\/j.physbeh.2004.02.004","article-title":"Motivation concepts in behavioral neuroscience","volume":"81","author":"Berridge","year":"2004","journal-title":"Physiol. 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Res."},{"key":"ref23","doi-asserted-by":"publisher","first-page":"10552","DOI":"10.1523\/JNEUROSCI.0051-13.2013","article-title":"Brain regions that represent Amodal conceptual knowledge","volume":"33","author":"Fairhall","year":"2013","journal-title":"J. Neurosci."},{"key":"ref24","doi-asserted-by":"publisher","first-page":"20170142","DOI":"10.1098\/rstb.2017.0142","article-title":"Grounding evaluative concepts","volume":"373","author":"Fingerhut","year":"2018","journal-title":"Philos. Trans. R. Soc. B Biol. 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Neuropsychol."},{"key":"ref28","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1002\/erv.2216","article-title":"Neural responses to visual food cues: insights from functional magnetic resonance imaging","volume":"21","author":"Garc\u00eda-Garc\u00eda","year":"2013","journal-title":"Eur. Eat. Disord. Rev."},{"key":"ref29","volume-title":"Foundations of Meaning: Primary Metaphors and Primary Scenes","author":"Grady","year":"1997"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1016\/s0896-6273(03)00838-9","article-title":"Somatotopic representation of action words in human motor and premotor cortex","volume":"41","author":"Hauk","year":"2004","journal-title":"Neuron"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1002\/oby.20659","article-title":"Neural bases of food perception: coordinate-based meta-analyses of neuroimaging studies in multiple modalities","volume":"22","author":"Huerta","year":"2014","journal-title":"Obesity"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003027","article-title":"The neural correlates of desire","volume":"3","author":"Kawabata","year":"2008","journal-title":"PLoS One"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1037\/a0023575","article-title":"Decision making and reward in frontal cortex","volume":"125","author":"Kennerley","year":"2011","journal-title":"Behav. 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Behav."},{"key":"ref44","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1038\/nrn3745","article-title":"Neurobiology of food intake in health and disease","volume":"15","author":"Morton","year":"2014","journal-title":"Nat. Rev. Neurosci."},{"key":"ref45","first-page":"36","volume-title":"The Psychology of Desire","author":"Papies","year":"2015"},{"key":"ref46","first-page":"217","volume-title":"Psychology of Learning and Motivation","author":"Pecher","year":"2011"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"110007","DOI":"10.1016\/j.isci.2024.110007","article-title":"Functional specialization of medial and lateral orbitofrontal cortex in inferential decision-making","volume":"27","author":"Qiu","year":"2024","journal-title":"iScience"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1007\/7854_2015_375","article-title":"The computational complexity of valuation and motivational forces in decision-making processes","volume":"27","author":"Redish","year":"2016","journal-title":"Curr. Top. Behav. Neurosci."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1007\/s00429-023-02644-9","article-title":"Emotion, motivation, decision-making, the orbitofrontal cortex, anterior cingulate cortex, and the amygdala","volume":"228","author":"Rolls","year":"2023","journal-title":"Brain Struct. Funct."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1186\/1479-5868-7-63","article-title":"When snacks become meals: how hunger and environmental cues bias food intake","volume":"7","author":"Shimizu","year":"2010","journal-title":"Int. J. Behav. Nutr. Phys. Act."},{"key":"ref51","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/j.bbr.2008.10.035","article-title":"Hunger is the best spice: an fMRI study of the effects of attention, hunger and calorie content on food reward processing in the amygdala and orbitofrontal cortex","volume":"198","author":"Siep","year":"2009","journal-title":"Behav. Brain Res."},{"key":"ref52","first-page":"31","volume-title":"The Routledge International Handbook of Neuroaesthetics","author":"Skov","year":"2023"},{"key":"ref53","doi-asserted-by":"publisher","first-page":"922","DOI":"10.1111\/febs.15791","article-title":"Hunger-driven adaptive prioritization of behavior","volume":"289","author":"Smith","year":"2022","journal-title":"FEBS J."},{"key":"ref54","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1080\/02699931.2014.925426","article-title":"Interoceptive ability predicts aversion to losses","volume":"29","author":"Sokol-Hessner","year":"2015","journal-title":"Cogn. Emot."},{"key":"ref55","doi-asserted-by":"publisher","first-page":"e22374","DOI":"10.1002\/dev.22374","article-title":"The development of interoceptive hunger signals","volume":"65","author":"Stevenson","year":"2023","journal-title":"Dev. Psychobiol."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"4569","DOI":"10.1073\/pnas.96.8.4569","article-title":"Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography","volume":"96","author":"Tataranni","year":"1999","journal-title":"Proc. Natl. Acad. Sci."},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1767","DOI":"10.1093\/cercor\/bht025","article-title":"The neural representation of abstract words: the role of emotion","volume":"24","author":"Vigliocco","year":"2014","journal-title":"Cereb. Cortex"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1123733","DOI":"10.3389\/fnbeh.2023.1123733","article-title":"Reward, motivation and brain imaging in human healthy participants \u2013 a narrative review","volume":"17","author":"Weinstein","year":"2023","journal-title":"Front. Behav. Neurosci."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.bbr.2010.04.021","article-title":"Cue-induced reinstatement of food seeking in rats that differ in their propensity to attribute incentive salience to food cues","volume":"214","author":"Yager","year":"2010","journal-title":"Behav. Brain Res."},{"key":"ref60","doi-asserted-by":"publisher","first-page":"2822","DOI":"10.1162\/jocn_a_02258","article-title":"Neural and computational mechanisms of motivation and decision-making","volume":"36","author":"Yee","year":"2024","journal-title":"J. Cogn. 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