{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T06:07:53Z","timestamp":1788847673436,"version":"build-2803163510"},"reference-count":95,"publisher":"Frontiers Media SA","license":[{"start":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T00:00:00Z","timestamp":1788825600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["frontiersin.org"],"crossmark-restriction":true},"short-container-title":["Front. Hum. Neurosci."],"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Peripersonal space (PPS) and interpersonal distance (IPD) reflect related but dissociable representations of the space around the body, both relevant to multisensory and social development. However, whether physical overgrowth is associated with an altered regulation of body-related space remains unknown, despite growing evidence of psychosocial difficulties in individuals with overgrowth syndromes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study aimed to characterize PPS and IPD in adolescents with overgrowth syndromes, specifically Beckwith-Wiedemann spectrum, Sotos syndrome, and Malan syndrome, and to test whether their expansion is associated with syndrome type, cognitive functioning, body size, and social-perceptual ability. Thirty-three adolescents with overgrowth syndromes and 33 age-matched controls completed separate comfort-distance and reachability judgments for social and non-social stimuli using a computerized stop-distance paradigm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Adolescents with overgrowth syndromes showed overall larger PPS and IPD than controls, independent of autistic traits (\n                      <jats:italic>p<\/jats:italic>\n                      \u202f&amp;lt;\u202f0.001,\n                      <jats:italic>\u03b7<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      <jats:italic>\n                        <jats:sub>p<\/jats:sub>\n                      <\/jats:italic>\n                      \u202f=\u202f0.25). Within the clinical group, the relative expansion of IPD over PPS was larger in adolescents with Beckwith-Wiedemann spectrum (\n                      <jats:italic>t<\/jats:italic>\n                      <jats:sub>31<\/jats:sub>\n                      \u202f=\u202f\u22122.57,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.015) and in those with average intellectual functioning (\n                      <jats:italic>t<\/jats:italic>\n                      <jats:sub>31<\/jats:sub>\n                      \u202f=\u202f\u22122.67,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.012), pointing to a buffer space linked to feelings of safety. A larger buffer space was further predicted by better affect-recognition skills (\n                      <jats:italic>\u03b2<\/jats:italic>\n                      \u202f=\u202f0.48,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.010), independent of age and autism-like social challenges. The body mass index was selectively associated with PPS (\n                      <jats:italic>r<\/jats:italic>\n                      \u202f=\u202f0.47,\n                      <jats:italic>p<\/jats:italic>\n                      \u202f=\u202f0.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>These findings indicate that body-related spatial representations are enlarged in overgrowth syndromes, and that this expansion is shaped by cognitive functioning, body size, and social-perceptual ability rather than by autistic traits, contributing novel evidence to the study of typical and atypical multisensory development and its association with social functioning. This may also inform interventions targeting social participation in adolescents with overgrowth syndromes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3389\/fnhum.2026.1951893","type":"journal-article","created":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:35:57Z","timestamp":1788845757000},"update-policy":"https:\/\/doi.org\/10.3389\/crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Peripersonal space and interpersonal distance as windows onto multisensory body representation in adolescents with overgrowth syndromes"],"prefix":"10.3389","volume":"20","author":[{"given":"Niccol\u00f2","family":"Butti","sequence":"first","affiliation":[{"name":"Scientific Institute, IRCCS E. Medea, 0-3 Centre for the at-risk infant, Bosisio Parini","place":["Lecco, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Montirosso","sequence":"additional","affiliation":[{"name":"Scientific Institute, IRCCS E. Medea, 0-3 Centre for the at-risk infant, Bosisio Parini","place":["Lecco, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Cartaud","sequence":"additional","affiliation":[{"name":"CNRS, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, University of Lille","place":["Villeneuve d'Ascq, France"]},{"name":"CNRS, IESEG School of Management, UMR 9221 - LEM - Lille \u00c9conomie Management, University of Lille","place":["Lille, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Oldrati","sequence":"additional","affiliation":[{"name":"Scientific Institute, IRCCS E. Medea, Laboratory of Neuroplasticity and Neuromodulation, Bosisio Parini","place":["Lecco, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yann","family":"Coello","sequence":"additional","affiliation":[{"name":"CNRS, UMR 9193 - SCALab - Sciences Cognitives et Sciences Affectives, University of Lille","place":["Villeneuve d'Ascq, France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cosimo","family":"Urgesi","sequence":"additional","affiliation":[{"name":"Scientific Institute, IRCCS E. Medea, Pasian di Prato","place":["Udine, Italy"]},{"name":"Department of Human and Social Sciences, Universitas Mercatorum","place":["Roma, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1965","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.bodyim.2023.02.008","article-title":"Social physical anxiety and eating disorders: a systematic review and meta-analysis","volume":"45","author":"Alcaraz-Ib\u00e1\u00f1ez","year":"2023","journal-title":"Body Image"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"1106228","DOI":"10.3389\/frcha.2023.1106228\/full","article-title":"Behavioral profiling in children and adolescents with Malan syndrome","volume":"2","author":"Alfieri","year":"2023","journal-title":"Front. Child Adolesc. Psychiatry."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1163\/22134808-bja10142","article-title":"Interpersonal distance preferences in deaf signers and hearing individuals","volume":"38","author":"Arioli","year":"2025","journal-title":"Multisens. Res."},{"key":"ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1242\/dmm.052300","article-title":"Overgrowth-intellectual disability disorders: progress in biology, patient advocacy and innovative therapies","volume":"18","author":"Atterton","year":"2025","journal-title":"Dis. Model. Mech."},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1230","DOI":"10.1007\/s10803-007-0504-z","article-title":"The autism spectrum quotient: children\u2019s version (AQ-child)","volume":"38","author":"Auyeung","year":"2008","journal-title":"J. Autism Dev. Disord."},{"key":"ref6","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s10803-006-0073-6","article-title":"The autism-Spectrum quotient (AQ) - adolescent version","volume":"36","author":"Baron-Cohen","year":"2006","journal-title":"J. Autism Dev. Disord."},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1007\/s00429-024-02781-9","article-title":"Neuroanatomical correlates of peripersonal space: bridging the gap between perception, action, emotion and social cognition","volume":"229","author":"Basile","year":"2024","journal-title":"Brain Struct. 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Genet."},{"key":"ref17","doi-asserted-by":"publisher","first-page":"107589","DOI":"10.1016\/j.neuropsychologia.2020.107589","article-title":"The plasticity of the interpersonal space in autism spectrum disorder","volume":"147","author":"Candini","year":"2020","journal-title":"Neuropsychologia"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1002\/aur.1637","article-title":"Personal space regulation in childhood autism: effects of social interaction and person\u2019s perspective","volume":"10","author":"Candini","year":"2017","journal-title":"Autism Res."},{"key":"ref19","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1177\/1362361318822504","article-title":"When social and action spaces diverge: a study in children with typical development and autism","volume":"23","author":"Candini","year":"2019","journal-title":"Autism"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s00221-013-3532-2","article-title":"Tool-use reshapes the boundaries of body and peripersonal space representations","volume":"228","author":"Canzoneri","year":"2013","journal-title":"Exp. 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J. Med. Genet. C: Semin. Med. Genet."},{"key":"ref35","doi-asserted-by":"publisher","first-page":"e0283761","DOI":"10.1371\/journal.pone.0283761","article-title":"Altered interpersonal distance regulation in autism spectrum disorder","volume":"18","author":"Farkas","year":"2023","journal-title":"PLoS One"},{"key":"ref36","doi-asserted-by":"publisher","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G*power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"Faul","year":"2007","journal-title":"Behav. Res. Methods"},{"key":"ref37","doi-asserted-by":"publisher","first-page":"111683","DOI":"10.1016\/j.isci.2024.111683","article-title":"Your space or mine: trait anxiety affects the peripersonal space plasticity in a social context","volume":"28","author":"Ferroni","year":"2025","journal-title":"iScience"},{"key":"ref38","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1016\/j.neuropsychologia.2014.09.043","article-title":"Moving sounds within the peripersonal space modulate the motor system","volume":"70","author":"Finisguerra","year":"2015","journal-title":"Neuropsychologia"},{"key":"ref39","doi-asserted-by":"publisher","first-page":"101777","DOI":"10.1016\/j.bodyim.2024.101777","article-title":"The impact of body image on social cognition: fear of negative evaluation mediates the relationship between body surveillance and interpersonal distance in women","volume":"51","author":"Finn","year":"2024","journal-title":"Body Image"},{"key":"ref40","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1152\/jn.1996.76.1.141","article-title":"Coding of peripersonal space in inferior premotor cortex (area F4)","volume":"76","author":"Fogassi","year":"1996","journal-title":"J. Neurophysiol."},{"key":"ref41","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.neuropsychologia.2005.05.008","article-title":"Is everybody always my friend? Perception of approachability in Williams syndrome","volume":"44","author":"Frigerio","year":"2006","journal-title":"Neuropsychologia"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1002\/aur.3013","article-title":"Greater interpersonal distance in adults with autism","volume":"16","author":"Fusaro","year":"2023","journal-title":"Autism Res."},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-023-27514-6","article-title":"The relationship between action, social and multisensory spaces","volume":"13","author":"Geers","year":"2023","journal-title":"Sci Reports"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"e74959","DOI":"10.1371\/journal.pone.0074959","article-title":"Personal space regulation in childhood autism spectrum disorders, Botbol M, editor.","volume":"8","author":"Gessaroli","year":"2013","journal-title":"PLoS One"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"e0306536","DOI":"10.1371\/journal.pone.0306536","article-title":"The relationship between interpersonal distance preference and estimation accuracy in autism","volume":"19","author":"Givon-Benjio","year":"2024","journal-title":"PLoS One"},{"key":"ref46","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1111\/an.1995.36","article-title":"Handbook for proxemic research","volume":"36","author":"Hall","year":"1995","journal-title":"Anthropol. News"},{"key":"ref47","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1086\/200975","article-title":"Proxemics [and comments and replies]","volume":"9","author":"Hall","year":"1968","journal-title":"Curr. Anthropol."},{"key":"ref48","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1007\/s10339-004-0013-3","article-title":"The body schema and multisensory representation(s) of peripersonal space","volume":"5","author":"Holmes","year":"2004","journal-title":"Cogn. Process."},{"key":"ref49","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1186\/s13023-024-03288-6","article-title":"Natural history in Malan syndrome: survey of 28 adults and literature review","volume":"19","author":"Huynh","year":"2024","journal-title":"Orphanet J. Rare Dis."},{"key":"ref50","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1371\/journal.pone.0111511","article-title":"Body space in social interactions: a comparison of reaching and comfort distance in immersive virtual reality","volume":"9","author":"Iachini","year":"2014","journal-title":"PLoS One"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.jenvp.2016.01.004","article-title":"Peripersonal and interpersonal space in virtual and real environments: effects of gender and age","volume":"45","author":"Iachini","year":"2016","journal-title":"J. Environ. Psychol."},{"key":"ref52","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.actpsy.2015.09.003","article-title":"Near or far? It depends on my impression: moral information and spatial behavior in virtual interactions","volume":"161","author":"Iachini","year":"2015","journal-title":"Acta Psychol."},{"key":"ref53","volume-title":"NEPSY\u2014Second Edition (NEPSY-II)","author":"Korkman","year":"2007"},{"key":"ref54","doi-asserted-by":"publisher","first-page":"00863","DOI":"10.3389\/fpsyg.2013.00863\/abstract","article-title":"Calculating and reporting effect sizes to facilitate cumulative science: a practical primer for t-tests and ANOVAs","volume":"4","author":"Lakens","year":"2013","journal-title":"Front. Psychol."},{"key":"ref55","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/B978-0-12-813796-3.00010-9","article-title":"Sotos syndrome","volume":"1","author":"Lane","year":"2019","journal-title":"Chromatin Signal Neurol Disord."},{"key":"ref56","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1007\/s10803-016-2941-z","article-title":"Characteristics of autism Spectrum disorder in Sotos syndrome","volume":"47","author":"Lane","year":"2017","journal-title":"J. Autism Dev. Disord."},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1475","DOI":"10.1007\/s10803-018-3842-0","article-title":"Parent-reported communication abilities of children with Sotos syndrome: evidence from the Children\u2019s Communication Checklist-2","volume":"49","author":"Lane","year":"2019","journal-title":"J. Autism Dev. Disord."},{"key":"ref58","doi-asserted-by":"publisher","first-page":"3207","DOI":"10.1007\/s10803-016-2864-8","article-title":"Personal space regulation in Williams syndrome: the effect of familiarity","volume":"46","author":"Lough","year":"2016","journal-title":"J. Autism Dev. Disord."},{"key":"ref59","doi-asserted-by":"publisher","first-page":"4101","DOI":"10.1007\/s10803-015-2536-0","article-title":"Violations of personal space in young people with autism spectrum disorders and Williams syndrome: insights from the social responsiveness scale","volume":"45","author":"Lough","year":"2015","journal-title":"J. Autism Dev. Disord."},{"key":"ref60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13023-022-02384-9","article-title":"A deep phenotyping experience: up to date in management and diagnosis of Malan syndrome in a single center surveillance report","volume":"17","author":"Macchiaiolo","year":"2022","journal-title":"Orphanet J. Rare Dis."},{"key":"ref61","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s00221-012-3089-5","article-title":"Keeping the world at hand: rapid visuomotor processing for hand\u2013object interactions","volume":"219","author":"Makin","year":"2012","journal-title":"Exp. Brain Res."},{"key":"ref62","doi-asserted-by":"publisher","first-page":"2968","DOI":"10.1093\/cercor\/bhaa404","article-title":"Neural correlates of interpersonal space permeability and flexibility in autism spectrum disorder","volume":"31","author":"Massaccesi","year":"2021","journal-title":"Cereb. 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Res."},{"key":"ref74","doi-asserted-by":"publisher","first-page":"105141","DOI":"10.1016\/j.neubiorev.2023.105141","article-title":"Relating different dimensions of bodily experiences: review and proposition of an integrative model relying on phenomenology, predictive brain and neuroscience of the self","volume":"148","author":"Raoul","year":"2023","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref75","doi-asserted-by":"publisher","first-page":"104655","DOI":"10.1016\/j.ridd.2023.104655","article-title":"Short report: autistic symptoms in Sotos syndrome, preliminary results from a case-control study","volume":"145","author":"Riccioni","year":"2024","journal-title":"Res. Dev. Disabil."},{"key":"ref76","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/0166-4328(81)90052-8","article-title":"Afferent properties of periarcuate neurons in macaque monkeys. I. Somatosensory responses","volume":"2","author":"Rizzolatti","year":"","journal-title":"Behav. Brain Res."},{"key":"ref77","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1016\/0166-4328(81)90053-X","article-title":"Afferent properties of periarcuate neurons in macaque monkeys. II. Visual responses","volume":"2","author":"Rizzolatti","year":"","journal-title":"Behav. Brain Res."},{"key":"ref78","doi-asserted-by":"publisher","first-page":"5170","DOI":"10.1038\/s41598-021-83988-2","article-title":"Defensive functions provoke similar psychophysiological reactions in reaching and comfort spaces","volume":"11","author":"Ruggiero","year":"2021","journal-title":"Sci. Rep."},{"key":"ref79","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s10803-011-1290-1","article-title":"The autism-Spectrum quotient\u2014Italian version: a cross-cultural confirmation of the broader autism phenotype","volume":"42","author":"Ruta","year":"2012","journal-title":"J. Autism Dev. Disord."},{"key":"ref80","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1016\/j.neubiorev.2019.01.016","article-title":"Peripersonal space (PPS) as a multisensory interface between the individual and the environment, defining the space of the self","volume":"99","author":"Serino","year":"2019","journal-title":"Neurosci. Biobehav. Rev."},{"key":"ref81","doi-asserted-by":"crossref","first-page":"18603","DOI":"10.1038\/srep18603","article-title":"Body part-centered and full body-centered peripersonal space representations","volume":"51","author":"Serino","year":"2015","journal-title":"Sci. Rep."},{"key":"ref82","doi-asserted-by":"publisher","first-page":"4317","DOI":"10.1007\/s10803-020-04484-6","article-title":"Virtual reality immersion rescales regulation of interpersonal distance in controls but not in autism spectrum disorder","volume":"50","author":"Sim\u00f5es","year":"2020","journal-title":"J. Autism Dev. Disord."},{"key":"ref83","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1037\/abn0000837","article-title":"Sensory processing in Sotos syndrome and Tatton-Brown\u2013Rahman syndrome","volume":"132","author":"Smith","year":"2023","journal-title":"J Psychopathol Clin Sci."},{"key":"ref84","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1177\/0022022117698039","article-title":"Preferred interpersonal distances: a global comparison","volume":"48","author":"Sorokowska","year":"2017","journal-title":"J. Cross-Cult. Psychol."},{"key":"ref85","doi-asserted-by":"publisher","first-page":"4202","DOI":"10.1016\/j.bjps.2022.08.042","article-title":"Appearance-related concerns and their impact on health-related quality of life in patients with peripheral vascular malformations","volume":"75","author":"Stor","year":"2022","journal-title":"J Plast Reconstr Aesthetic Surg."},{"key":"ref86","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.actpsy.2016.01.012","article-title":"Perceived distance and obesity: it\u2019s what you weigh, not what you think","volume":"165","author":"Sugovic","year":"2016","journal-title":"Acta Psychol."},{"key":"ref87","doi-asserted-by":"publisher","first-page":"31390","DOI":"10.1007\/s12144-022-04157-w","article-title":"Interpersonal distance modulates outcome evaluation in the social comparison of ability","volume":"42","author":"Sun","year":"2023","journal-title":"Curr. Psychol."},{"key":"ref88","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/BF01531456","article-title":"Interpersonal relationships and personal space: research review and theoretical model","volume":"4","author":"Sundstrom","year":"1976","journal-title":"Hum. Ecol."},{"key":"ref89","volume-title":"NEPSY-II, Contributo alla Taratura Italiana","author":"Urgesi","year":"2011"},{"key":"ref90","doi-asserted-by":"publisher","first-page":"1492","DOI":"10.1002\/hbm.23467","article-title":"Emotion and personal space: neural correlates of approach-avoidance tendencies to different facial expressions as a function of coldhearted psychopathic traits","volume":"38","author":"Vieira","year":"2017","journal-title":"Hum. Brain Mapp."},{"key":"ref91","doi-asserted-by":"publisher","first-page":"e64129","DOI":"10.1002\/ajmg.a.64129","article-title":"The behavioral phenotype and importance of multidisciplinary care in patients with Sotos syndrome: a single-center experience","author":"Viswanathan","year":"2025","journal-title":"Am. J. Med. Genet. A"},{"key":"ref92","doi-asserted-by":"publisher","first-page":"562","DOI":"10.3389\/fped.2019.00562","article-title":"Diagnosis and Management of Beckwith-Wiedemann Syndrome","volume":"7","author":"Wang","year":"2020","journal-title":"Front. Pediatr."},{"key":"ref93","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1111\/jasp.13056","article-title":"The role of group membership and culture in interpersonal distance regulation","volume":"54","author":"Wei","year":"2024","journal-title":"J. Appl. Soc. Psychol."},{"key":"ref94","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.3758\/s13423-021-01942-9","article-title":"Peripersonal and reaching space differ: evidence from their spatial extent and multisensory facilitation pattern","volume":"286","author":"Zanini","year":"2021","journal-title":"Psychon. Bull. Rev."},{"key":"ref95","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1152\/jn.00157.2021","article-title":"Associative learning in peripersonal space: fear responses are acquired in hand-centered coordinates","volume":"126","author":"Zanini","year":"2021","journal-title":"J. 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